1.Which of the following tissues can use glucose, but not fatty Acids, as a source of
fuel?
A. Skeletal Muscle
B. Cardiac tissue
C. Liver
D. Red Blood Cells
E. Adipose:
D. Red Blood Cells
__________
Brain and RBC
2.Within the red blood cell, NADPH is required for which of the following processes?
A. The Conversion of pyruvate to Acetyl CoA
B. The Oxidation of hemoglobin
C. The conversion of pyruvate to lactate
D.The synthesis of ribulose 5-Phosphate
E. The Reduction of Glutathione:
Answer: E. The Reduction of Glutathione
3.There are several anaplerotic reactions required to replenish intermediates of the TCA
cycle. All of the following compounds can be used for these anaplerotic reactions
EXCEPT:
A. Aspartate
B. Propionyl
C. Glutamate
D.Odd Chain fatty acids
E. Glucose:
Answer: E. Glucose
,_________________________________
CAN BE USED: Pyruvate, Aspartate, Glutamate, Beta Oxidation of fatty acids,
adenylosuccinate; PEP carboxylase and malate dehydrogenase; Glutamine
4.Hereditary fructose intolerance is a rare recessive disease caused by a mutation in
exon 5. The mutation creates a new Ahall restriction within the exon. In this graphic:
--------- --------- 306
===== --------- ===== --------- 183
===== --------- ===== --------- 123
husband wife jack jill
a) the husband had al b deficiency
b) the wife has 2 wild allells
c) Jill has wild recessive
d) jack and jill have same genes:
Answer: b) the wife has 2 wild allells
5.A 3yearold boy who presented with generalized hypotonia, severe psychomotor
development delay, and severe lactic acidosis following ingestion of a high carbohydrate
meal was diagnosed with a deficiency in pyruvate dehydrogenase (Xlinked recessive).
Supplementation of which vitamin may be beneficial to this individual:
A. Pyridoxal Phosphate (PLP)
B. Folate
C. Cobalmin (B12)
D. Thiamine:
Answer: D. Thiamine
6.Which of the following hormones binds to a receptor tyrosine kinase?
, A. Epinephrine
B. Cortisol
C. Glucagon
D. Insulin:
Answer: D. Insulin
Receptor tyrosine kinase are the highaffinity cell surface receptors for many polypeptide growth
factors, cytokines, and hormones. Tyrosine kinase contain insulin growth factor which can bind
to glucogan
7.Which of the following is true regarding single point mutations to a genomic DNA
sequence?
A . changes to the DNA sequence will always result in an amino acid change in the primary sequence
B. single nucleotide changes to the DNA sequence may have no impact on the primary sequence of a
protein
C. single nucleotide changes to DNA will always introduce a frame shif
D. single nucleotide changes will always introduce a nonsense mutation:
Answer:B
8.NADH generated in the cytosol must be transported across the mitochondrial
membrane in order to be oxidized by the electron transport chain. Which can be used to
facilitate movement of cytosolic NADH into the mitochodria?
a) Malate-aspartate shuttle
b) GLUT 4 Transport
c) Citrate chuttle
d) Na/K+ ATPase pump:
fuel?
A. Skeletal Muscle
B. Cardiac tissue
C. Liver
D. Red Blood Cells
E. Adipose:
D. Red Blood Cells
__________
Brain and RBC
2.Within the red blood cell, NADPH is required for which of the following processes?
A. The Conversion of pyruvate to Acetyl CoA
B. The Oxidation of hemoglobin
C. The conversion of pyruvate to lactate
D.The synthesis of ribulose 5-Phosphate
E. The Reduction of Glutathione:
Answer: E. The Reduction of Glutathione
3.There are several anaplerotic reactions required to replenish intermediates of the TCA
cycle. All of the following compounds can be used for these anaplerotic reactions
EXCEPT:
A. Aspartate
B. Propionyl
C. Glutamate
D.Odd Chain fatty acids
E. Glucose:
Answer: E. Glucose
,_________________________________
CAN BE USED: Pyruvate, Aspartate, Glutamate, Beta Oxidation of fatty acids,
adenylosuccinate; PEP carboxylase and malate dehydrogenase; Glutamine
4.Hereditary fructose intolerance is a rare recessive disease caused by a mutation in
exon 5. The mutation creates a new Ahall restriction within the exon. In this graphic:
--------- --------- 306
===== --------- ===== --------- 183
===== --------- ===== --------- 123
husband wife jack jill
a) the husband had al b deficiency
b) the wife has 2 wild allells
c) Jill has wild recessive
d) jack and jill have same genes:
Answer: b) the wife has 2 wild allells
5.A 3yearold boy who presented with generalized hypotonia, severe psychomotor
development delay, and severe lactic acidosis following ingestion of a high carbohydrate
meal was diagnosed with a deficiency in pyruvate dehydrogenase (Xlinked recessive).
Supplementation of which vitamin may be beneficial to this individual:
A. Pyridoxal Phosphate (PLP)
B. Folate
C. Cobalmin (B12)
D. Thiamine:
Answer: D. Thiamine
6.Which of the following hormones binds to a receptor tyrosine kinase?
, A. Epinephrine
B. Cortisol
C. Glucagon
D. Insulin:
Answer: D. Insulin
Receptor tyrosine kinase are the highaffinity cell surface receptors for many polypeptide growth
factors, cytokines, and hormones. Tyrosine kinase contain insulin growth factor which can bind
to glucogan
7.Which of the following is true regarding single point mutations to a genomic DNA
sequence?
A . changes to the DNA sequence will always result in an amino acid change in the primary sequence
B. single nucleotide changes to the DNA sequence may have no impact on the primary sequence of a
protein
C. single nucleotide changes to DNA will always introduce a frame shif
D. single nucleotide changes will always introduce a nonsense mutation:
Answer:B
8.NADH generated in the cytosol must be transported across the mitochondrial
membrane in order to be oxidized by the electron transport chain. Which can be used to
facilitate movement of cytosolic NADH into the mitochodria?
a) Malate-aspartate shuttle
b) GLUT 4 Transport
c) Citrate chuttle
d) Na/K+ ATPase pump:
