NSG6005 MIDTERM EXAM (VERSION-1).

NSG6005 MIDTERM EXAM I I I




1) A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to
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prescribing because: Distribution of drugs to target tissue may be affected.
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2) Drugs that have a significant first-pass effect: Are rapidly metabolized by the liver and
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may have little if any desired action.
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3) The route of excretion of a volatile drug will likely be: The lungs
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4) The point in time on the drug concentration curve that indicates the first sign of a
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therapeutic effect is the: Onset of action
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5) Factors that affect gastric drug absorption include: Lipid solubility of the drug
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6) Which one of the following statements about bioavailability is true? Bioavailability
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issues are especially important for drugs with narrow therapeutic ranges or sustained
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release mechanisms.
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7) Steady state is: When the amount of drug in the body remains constant.
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8) The time required for the amount of drug in the body to decrease by 50% is called: Half-
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life
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9) An advantage of prescribing a sublingual medication is that the medication is: Absorbed
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rapidly
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10) Drugs that use CYP3A4 isoenzymes for metabolism may: Both A and B(Induce the
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metabolism of another drug; inhibit the metabolism of another drug)

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11) A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
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because: A six-year-old may have problems swallowing a pill
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12) The first step in the prescribing process according to the World Health Organization is:

Diagnosing the patient’s problem
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13) Patient education regarding prescribed medication includes: Discussion of expected
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ADRs
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14) Pharmacokinetic factors that affect prescribing include: Bioavailability
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15) Infants and young children are at higher risk of ADRs due to: Lack of safety and efficacy
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studies in the pediatric population.
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16) Infants and young children are at higher risk of ADRs due to: Lack of safety and efficacy
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studies in the pediatric population.
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17) The elderly are at high risk of ADRs due to: Age-related decrease in renal-function
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18) The type of ADR that is the result of an unwanted but otherwise normal pharmacological
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action of a drug given in the usual therapeutic doses is: Type A
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19) A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia
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is: A cytoxic hypersensitivity reaction
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20) The angiotensin converting enzyme (ACE) inhibitor Lisinopril is a known teratogen.
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Teratogens cause Type __ ADR. D
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21) A twenty-four-year-old male received multiple fractures in a motor vehicle accident that
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required significant amounts of opioid medication to treat his pain. He is at risk for Type
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__ ADR when he no longer requires the opioids. E

22) Which of the following factors may adversely affect a patient’s adherence to a therapeutic
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drug regimen? Both A and B