U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
U World – NCLEX STUDY
NOTES
Pharmacology
• Afib
o Warfarin
▪ INR 2-3
▪ Affected by antibiotics (destroy bacteria which produce vitamin
K,
increasing INR)
▪ Leafy greens can lower INR
▪ Omeprazole, Amiodarone, Tylenol, NSAIDs, SSRIs, Thyroid
hormone ^ bleeding risk
o Digoxin (Lanoxin)
▪ Increase cardiac contractility but slows heart rate and
conduction
o Macrolide (azithromycin, erythromycin, clarithromycin)
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
,U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
▪ Can cause prolonged QT interval, which may lead to cardiac
death due to torsades de pointes
▪ can cause hepatotoxicity
o Penicillin (amoxicillin,
ampicillin)
▪ Allergy may have cross-sensitivity to cephalosporin (cefazolin,
cephalexin, ceftriaxone)
o “Sulfa” medications (trimethoprim, sulfamethoxazole, sulfasalazine)
▪ Side effects: crystalluria causing kidney injury (drink at least
8 glasses of water), photosensitivity, folic acid deficiency,
agranulocytosis, stevens- johnson syndrome
• Stop taking if rash develops, monitor CBC and report
fever and sore throat immediately.
o Tetracyclines (tetracycline, doxycycline, minocycline)
▪ Take on empty stomach (1 hour before or 2 hour after meals)
▪ Avoid antacids, iron supplements or dairy products
▪ Take with full glass of water
▪ Photosensitivity
▪ Can decrease effectiveness of contraceptives (is teratogenic
also)
• Antidotes
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
,U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
o Benztropine (Congentin), Diphenhydramine hydrochloride (Benadryl)
▪ Treats extrapyramidal effects associated with antipsychotic
medications
▪ Anticholinergic effects
o Calcium Gluconate
▪ Reverses magnesium toxicity
o Dantrolene
▪ Malignant hyperthermia
o Flumazenil (Romazicon)
▪ Reverses the effects of benzodiazepines (ex. Midazolam;
versed)
o Phentolamine (Regitine)
▪ Treat norepinephrine or dopamine extravasation
▪ Excreted by kidney, need to check kidney function
• ADHD
o Methylphenidate (Ritalin, Concerta)
▪ Side effects: loss of appetite (resulting in weight loss),
increased BP and tachycardia
▪ Very important to compare height/weight measures once
weekly
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
, U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
▪ Preferably given before meals, but can be given after if it affects
appetite
• Alcoholism
o Disulfiram (Antabuse)
▪ Unpleasant side effects (headache, N+V, dyspnea,
tachycardia, hypotension, confusion) when digesting
alcohol
▪ Can be fatal if taking large amounts
▪ Not a cure; need to continue seeing a therapist
▪ Abstain from alcohol post 2 weeks after last dose
▪ Wear a bracelet alerting others of therapy
o Thiamine (B1)
▪ IV thiamine is given before or with IV glucose to a client
with alcohol intoxication to prevent Wernicke
encephalopathy.
• Allergy
o Antihistamines (diphenhydramine [Benadryl], loratadine [claratin],
promethazine
[Phenergan], pseudoephedrine)
▪ Do not give Benadryl to child
• Antibiotics
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
U World – NCLEX STUDY
NOTES
Pharmacology
• Afib
o Warfarin
▪ INR 2-3
▪ Affected by antibiotics (destroy bacteria which produce vitamin
K,
increasing INR)
▪ Leafy greens can lower INR
▪ Omeprazole, Amiodarone, Tylenol, NSAIDs, SSRIs, Thyroid
hormone ^ bleeding risk
o Digoxin (Lanoxin)
▪ Increase cardiac contractility but slows heart rate and
conduction
o Macrolide (azithromycin, erythromycin, clarithromycin)
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
,U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
▪ Can cause prolonged QT interval, which may lead to cardiac
death due to torsades de pointes
▪ can cause hepatotoxicity
o Penicillin (amoxicillin,
ampicillin)
▪ Allergy may have cross-sensitivity to cephalosporin (cefazolin,
cephalexin, ceftriaxone)
o “Sulfa” medications (trimethoprim, sulfamethoxazole, sulfasalazine)
▪ Side effects: crystalluria causing kidney injury (drink at least
8 glasses of water), photosensitivity, folic acid deficiency,
agranulocytosis, stevens- johnson syndrome
• Stop taking if rash develops, monitor CBC and report
fever and sore throat immediately.
o Tetracyclines (tetracycline, doxycycline, minocycline)
▪ Take on empty stomach (1 hour before or 2 hour after meals)
▪ Avoid antacids, iron supplements or dairy products
▪ Take with full glass of water
▪ Photosensitivity
▪ Can decrease effectiveness of contraceptives (is teratogenic
also)
• Antidotes
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
,U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
o Benztropine (Congentin), Diphenhydramine hydrochloride (Benadryl)
▪ Treats extrapyramidal effects associated with antipsychotic
medications
▪ Anticholinergic effects
o Calcium Gluconate
▪ Reverses magnesium toxicity
o Dantrolene
▪ Malignant hyperthermia
o Flumazenil (Romazicon)
▪ Reverses the effects of benzodiazepines (ex. Midazolam;
versed)
o Phentolamine (Regitine)
▪ Treat norepinephrine or dopamine extravasation
▪ Excreted by kidney, need to check kidney function
• ADHD
o Methylphenidate (Ritalin, Concerta)
▪ Side effects: loss of appetite (resulting in weight loss),
increased BP and tachycardia
▪ Very important to compare height/weight measures once
weekly
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
, U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
▪ Preferably given before meals, but can be given after if it affects
appetite
• Alcoholism
o Disulfiram (Antabuse)
▪ Unpleasant side effects (headache, N+V, dyspnea,
tachycardia, hypotension, confusion) when digesting
alcohol
▪ Can be fatal if taking large amounts
▪ Not a cure; need to continue seeing a therapist
▪ Abstain from alcohol post 2 weeks after last dose
▪ Wear a bracelet alerting others of therapy
o Thiamine (B1)
▪ IV thiamine is given before or with IV glucose to a client
with alcohol intoxication to prevent Wernicke
encephalopathy.
• Allergy
o Antihistamines (diphenhydramine [Benadryl], loratadine [claratin],
promethazine
[Phenergan], pseudoephedrine)
▪ Do not give Benadryl to child
• Antibiotics
U WORLD- NCLEX REVISION STIUDY GUIDE NOTES
LATEST UPDATE BEST EXAM SOLUTION
RATED/UPGRADED A+
