NURSING 101Chapter 47: Alterations of the Integument in Children

Which immunoglobulin (Ig) is elevated in atopic dermatitis? a. IgA c. IgE b. IgM d. IgG ANS: C In the acute phase of atopic dermatitis, inflammation is associated with the activation of T helper 1 (Th-1) cells with an overexpression of cytokines (interleukin [IL]Ð4, IL-5, and IL13) and chemokine ligand 1 (CCL1) and 18 (CCL18) with increases in IgE, eosinophils, and macrophages. The remaining options will not be elevated as related to atopic dermatitis. PTS: 1 REF: Page 1654 2. Which leukocytes are elevated in atopic dermatitis? a. Eosinophils c. Basophils b. Neutrophils d. Monocytes ANS: A In the acute phase of atopic dermatitis, inflammation is associated with the activation of T helper 1 (Th-1) cells with an overexpression of cytokines (interleukin [IL]Ð4, IL-5, and IL13) and chemokine ligand 1 (CCL1) and 18 (CCL 18) with increases in IgE, eosinophils, and macrophages. Other leukocytes will not be elevated as related to atopic dermatitis. PTS: 1 REF: Page 1654 3. Which clinical manifestation is considered the hallmark of atopic dermatitis? a. Papular rash c. Vesicles that burst and form crusts b. High fever d. Itching ANS: D