7th Edition by Joyce - Sally
Clinical Calculations With Applications to
General And Specialty Areas 7th Edition by
Joyce – Sally M. – Test Bank
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Clinical Calculations With Applications to General And Specialty Areas
7th Edition by Joyce – Sally M. – Test Bank
Sample Questions
Chapter 7: Methods of Calculation for Individualized Drug Dosing
OTHER
Body Surface Area by Square Root
,Clinical Calculations With Applications to General And Specialty Areas
7th Edition by Joyce - Sally
1. Order: cyclophosphamide 500 mg/m2 in 500 mL of normal
saline solution (NSS) over 90 minutes
Patient height and weight: 5 ft 10 in, 142 lb
Drug available: cyclophosphamide 100 mg dilute with 5 mL of
sterile water; yields 20 mg/mL
1. What is the patient’s body surface area (BSA) (m2)?
2. What is the total dose?
3. How many milliliters should you prepare?
ANS:
1.
1. 500 mg/m2 ´ 1.78 m2 = 890 mg
1. FE: 890 mg/100 mg ´ 5 mL = 44.5 mL
OR
1. Order: cisplatin 50 mg/m2 in 500 mL of NSS intravenously over
90 minutes
Patient height and weight: 5 ft 6 in, 160
lb Drug available: cisplatin 100 mg/100
mL
1. What is the patient’s BSA (m2)?
2. What is the total dose?
3. How many milliliters should you prepare?
,Clinical Calculations With Applications to General And Specialty Areas
7th Edition by Joyce - Sally
ANS:
, Clinical Calculations With Applications to General And Specialty Areas
7th Edition by Joyce - Sally
1.
b.50 mg ´ 1.83 m2 = 91.5 mg
1. FE: 91.5 mg/100 mg ´ 100 mL = 91.5 mL or 92 mL
OR
For Questions 3 through 18, use the square root method and/or
nomogram. Note discrepancies between methods.
1. Give dacarbazine 250 mg/m2/day ´ 5 days.
Patient height: 5 ft 10
in Patient weight: 173
lb What is the daily
dose with:
1. square root method?
2. nomogram?
ANS:
1.
250 mg/m2/day ´ 1.96 m2 = 490 mg/day
1. Height 70 in, weight 173 lb, intersects
2.02 m2 250 mg/m2/day ´ 2.02 m2 = 505 500