HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
ATI Pharmacology
IMPORTANT LAB VALUES
• Sodium (Na): 136-145 mEq/L
• Calcium: 9.0-10 mg/dL
• Chloride: 98-106 mEq/L
• Bicarb HCO3: 21-28 mEq/L
• Potassium: 3.5-5.0 mg/L
• Phosphorus PO4 : 3.0-4.5 mg/dL
• Magnesium: 1.3- 2.1 mEq/L
• Cholesterol:
o Total <200mg/dL
o LDL ("bad") <100
o HDL ("good) >40
o Triglycerides <150mg/dL
• Liver enzymes
o ALT/SGPT 8-20 units/L
o AST/SGOT 5-40 units/L
o ALP 42-128 units/L
o Total protein 6-8 gm/dL
• Pancreatic enzymes
o Amylase 56-90 IU/L
o Lipase 0-110 units/L
o Prothrombin time 0.8-1.2
• Glucose:
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
,HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
Preprandial (fasting) 70-110
mg/dL Postprandial 70-140
mg/dL
• RBC: Females 4.2-5.4 million/uL; Males 4.7-6.1 million /uL
• WBC: 5000 -10,000
• Iron: Females 60-160 mcg/dL; Males 80-180 mcg/dL
• Platelets: 150,000-450,000
• Hemoglobin (Hgb): Females 12-16 g/dL; Males 14-18 g/dL
• Hematocrit (Hct): Females 37-47%;Males 42-52%
• Prothrombin Time (PT): 11-14 seconds: therapeutic range 1.5-2x
normal or control value
• Urine specific gravity: 1.015-1.030
• Urine pH: average 6.0; range 4.6-8.0
• BUN: 10-20 mg/dL
• Creatinine: female 0.5-1.1, males 0.6 - 1.2 mg/dL;
• Creatinine phosphokinase MB (CK-MB): normal 30-170 units/L
*increase 4-6 hrs after MI and remains elevated 24-72hrs
• Troponin normal: <0.2 ng/dL *gold standard for MI
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
,HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
- Endocrine Disorders: Identifying a Need for a Dosage Increase of
Ch. 40)
Levothyroxine (Active Learning Template - Medication, RM Pharm RN 7.0
1) Binding agents, antiulcer medications, calcium and iron supplements, and
food reduce levothyroxine absorption with concurrent use (4 hours
between)
2) Many antiseizure and antidepressant medications, including carbamazepine,
phenytoin, phenobarbital, and sertraline, can increase levothyroxine metabolism
(dosages may need to be increased)
3) Levothyroxine can increase the anticoagulant effects of warfarin by breaking
down vitamin K (monitor INR & PT; report signs of bleeding; warfarin dosages
may need to be decreased)
4) Daily therapy begins with a low dose that increases gradually over several
weeks. Full effect of medication can take 6 to 8 week
5) Instruct clients to take the medication daily on an empty stomach 30 to
60 min before breakfast.
- Safe Medication Administration and Error Reduction: Reviewing a
Medication Administration Record (RN QSEN - Teamwork and
Collaboration, Active Learning Template - Nursing Skill, RM Pharm
RN 7.0 Ch. 2)
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
, HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
1) Report all errors, and implement corrective measures immediately
2) Complete an incident report within the time frame the facility specifies, usually
24 hr.
3) Do not reference or include this report in the client's medical record
4) Evaluate clients' responses to medications, and document and report them.
5) Identify side and adverse effects, and document and report them.
Chapter 12
- Substance Use Disorders: Therapeutic effect of chlordiazepoxide (Ch. 12
pg.85)
- Substance Use Disorders: Smoking cessation using bupropion (Ch. 12 pg. 87)
- Substance Use Disorders: Treatment for Cocaine Toxicity (Active
Learning Template - System Disorder, RM Pharm RN 7.0 Ch. 12)
1) First line treatment = Benzodiazepines (to reduce CNS & cardiovascular effects)
2) Chlordiazepoxide, diazepam, lorazepam, clorazepate, oxazepam
3) Provide seizure precautions
4) Manifestations include nausea; vomiting; tremors; restlessness and
inability to sleep; depressed mood or irritability; increased heart rate,
blood pressure, respiratory rate, and temperature; diaphoresis; and tonic-
clonic seizures. Illusions are also common
5) Monitor vitals and neurological status on a regular basis
Chapter 13
- Chronic Neurologic Disorders: Adverse effects of neostigmine
(Ch. 13 pg. 91) Adverse effects:
Excessive muscarinic
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
RATED A+
ATI Pharmacology
IMPORTANT LAB VALUES
• Sodium (Na): 136-145 mEq/L
• Calcium: 9.0-10 mg/dL
• Chloride: 98-106 mEq/L
• Bicarb HCO3: 21-28 mEq/L
• Potassium: 3.5-5.0 mg/L
• Phosphorus PO4 : 3.0-4.5 mg/dL
• Magnesium: 1.3- 2.1 mEq/L
• Cholesterol:
o Total <200mg/dL
o LDL ("bad") <100
o HDL ("good) >40
o Triglycerides <150mg/dL
• Liver enzymes
o ALT/SGPT 8-20 units/L
o AST/SGOT 5-40 units/L
o ALP 42-128 units/L
o Total protein 6-8 gm/dL
• Pancreatic enzymes
o Amylase 56-90 IU/L
o Lipase 0-110 units/L
o Prothrombin time 0.8-1.2
• Glucose:
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
,HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
Preprandial (fasting) 70-110
mg/dL Postprandial 70-140
mg/dL
• RBC: Females 4.2-5.4 million/uL; Males 4.7-6.1 million /uL
• WBC: 5000 -10,000
• Iron: Females 60-160 mcg/dL; Males 80-180 mcg/dL
• Platelets: 150,000-450,000
• Hemoglobin (Hgb): Females 12-16 g/dL; Males 14-18 g/dL
• Hematocrit (Hct): Females 37-47%;Males 42-52%
• Prothrombin Time (PT): 11-14 seconds: therapeutic range 1.5-2x
normal or control value
• Urine specific gravity: 1.015-1.030
• Urine pH: average 6.0; range 4.6-8.0
• BUN: 10-20 mg/dL
• Creatinine: female 0.5-1.1, males 0.6 - 1.2 mg/dL;
• Creatinine phosphokinase MB (CK-MB): normal 30-170 units/L
*increase 4-6 hrs after MI and remains elevated 24-72hrs
• Troponin normal: <0.2 ng/dL *gold standard for MI
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
,HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
- Endocrine Disorders: Identifying a Need for a Dosage Increase of
Ch. 40)
Levothyroxine (Active Learning Template - Medication, RM Pharm RN 7.0
1) Binding agents, antiulcer medications, calcium and iron supplements, and
food reduce levothyroxine absorption with concurrent use (4 hours
between)
2) Many antiseizure and antidepressant medications, including carbamazepine,
phenytoin, phenobarbital, and sertraline, can increase levothyroxine metabolism
(dosages may need to be increased)
3) Levothyroxine can increase the anticoagulant effects of warfarin by breaking
down vitamin K (monitor INR & PT; report signs of bleeding; warfarin dosages
may need to be decreased)
4) Daily therapy begins with a low dose that increases gradually over several
weeks. Full effect of medication can take 6 to 8 week
5) Instruct clients to take the medication daily on an empty stomach 30 to
60 min before breakfast.
- Safe Medication Administration and Error Reduction: Reviewing a
Medication Administration Record (RN QSEN - Teamwork and
Collaboration, Active Learning Template - Nursing Skill, RM Pharm
RN 7.0 Ch. 2)
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
, HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+
1) Report all errors, and implement corrective measures immediately
2) Complete an incident report within the time frame the facility specifies, usually
24 hr.
3) Do not reference or include this report in the client's medical record
4) Evaluate clients' responses to medications, and document and report them.
5) Identify side and adverse effects, and document and report them.
Chapter 12
- Substance Use Disorders: Therapeutic effect of chlordiazepoxide (Ch. 12
pg.85)
- Substance Use Disorders: Smoking cessation using bupropion (Ch. 12 pg. 87)
- Substance Use Disorders: Treatment for Cocaine Toxicity (Active
Learning Template - System Disorder, RM Pharm RN 7.0 Ch. 12)
1) First line treatment = Benzodiazepines (to reduce CNS & cardiovascular effects)
2) Chlordiazepoxide, diazepam, lorazepam, clorazepate, oxazepam
3) Provide seizure precautions
4) Manifestations include nausea; vomiting; tremors; restlessness and
inability to sleep; depressed mood or irritability; increased heart rate,
blood pressure, respiratory rate, and temperature; diaphoresis; and tonic-
clonic seizures. Illusions are also common
5) Monitor vitals and neurological status on a regular basis
Chapter 13
- Chronic Neurologic Disorders: Adverse effects of neostigmine
(Ch. 13 pg. 91) Adverse effects:
Excessive muscarinic
HCO 3ATI Pharmacology Proctored 2.STUDY GUIDE
RATED A+