NURSING 101 NEURO DRUGS EXAM (Sympathetic N ervous System)

NURSING 101 NEURO DRUGS EXAM (Sympathetic
Nervous System)

-Sympathetic nervous system

Adrenergic receptors

-Alpha
-Alpha 1
-in all sympathetic target organs (except heart)
**response:
-constrict blood vessels, dilate pupils,
goose bumps, decreased GI effects
-Alpha 2
-activation inhibits release of NE
-negative feedback to stop neurotransmitter release
-Beta
-Beta 1
-in heart and kidneys, cardio-selective
**response:
-activation increases heart rate and
force of heart contraction, increases the release of renin
-Beta 2
-in all sympathetic target organs except the heart
**response:
-inhibits smooth muscle:
bronchodilation,
-Beta 3
**response:
-relax muscle in the bladder, lipolysis
and thermogenisis, cardioprotective

, -Parasympathetic nervous system

Cholinergic receptors

-Nicotinic receptors
-in sympathetic and parasympathetic postganglionic
neuron cell bodies
**response: stimulate smooth muscle and gland
secretion
*not used for meds

-Muscarinic receptors
-in parasympathetic target organs (EXCEPT heart)
**response: stimulate smooth muscle and gland
secretion
*used for meds: increase rest and digest
response and decrease
HR