Frazier: Essentials of Human Diseases and Conditions, 5th Edition
Test Bank
Chapter 1: Mechanisms of Disease, Diagnosis, and Treatment
MULTIPLE CHOICE
1. Signs of disease
a. always cause symptoms.
b. rarely correlate with symptoms.
c. include abnormal objective findings.
d. are always described by the patient.
ANS: C
2. Predisposing factors of disease
a. precisely predict the occurrence of disease.
b. make a person or group more vulnerable to disease.
c. never overlap or occur in combination.
d. can all be controlled by prevention.
ANS: B
3. Genetic diseases may be
, a. produced by an abnormality in or mutation of the genetic code in a single gene.
b. caused by several abnormal genes.
c. caused by the abnormal presence or absence of a chromosome or an alteration of
the structure of chromosomes.
d. all of the above.
ANS: D
4. Benign tumors
a. tend to remain encapsulated.
b. infiltrate surrounding tissue.
c. do not compress surrounding tissue or obstruct organs.
d. do not resemble the tissue of origin.
ANS: A
5. Malignant tumors
a. tend to infiltrate other tissue.
b. tend to bleed, ulcerate, and become infected.
c. may spread to distant sites in the body.
d. are all of the above.
ANS: D
6. Which statement is true regarding the TNM (tumor, nodes, metastasis) cancer staging
system?
a. Assesses the size and extent of the spread of the primary tumor.
, b. Is a grading system based on the degree of differentiation of tumor cells.
c. Both a and b are true.
d. Neither a nor b is true.
ANS: A
7. Which of the following correctly states the sequence of an allergic response within the
body most?
a. IgE antibodies enter the body and produce an allergen.
b. The release of histamine sensitizes mast cells and produces symptoms.
c. Exposure to allergen stimulates production of IgE antibodies that can subsequently
trigger symptoms of allergy.
d. Histamine produces mast cells, which stimulate plasma cells.
ANS: C
8. Which of the following most accurately states the orderly steps in making a diagnosis?
a. Medical history, physical examination, diagnostic tests, diagnosis, integration of
results, treatment
b. Medical history, diagnostic tests, physical examination, treatment plan
c. Physical examination, medical history, radiographs, prognosis, integration of all
information
d. Comparison of normals, physical examination, history, treatment plan, prognosis
ANS: A
9. Mechanical and chemical barriers, the inflammatory response, and the immune response
are
, a. risk factors for disease.
b. the combined effects of inheritance and environmental factors.
c. included in the body’s natural defense system against infection.
d. agents that damage DNA.
ANS: C
10. Immune disorders are the result of a breakdown in the body’s defense system that may
generate
a. allergy.
b. autoimmune diseases.
c. immunodeficiency disorders.
d. all of the above.
ANS: D
11. Immunodeficiency disorders result from
a. an exudative response.
b. physical trauma.
c. motor vehicle accidents.
d. a depressed or absent immune response.
ANS: D
12. Which statement(s) is (are) correct regarding autoimmune diseases?
a. The disease allows the immune system to become self-destructive.
b. Many serious diseases have a strong autoimmune component.
Test Bank
Chapter 1: Mechanisms of Disease, Diagnosis, and Treatment
MULTIPLE CHOICE
1. Signs of disease
a. always cause symptoms.
b. rarely correlate with symptoms.
c. include abnormal objective findings.
d. are always described by the patient.
ANS: C
2. Predisposing factors of disease
a. precisely predict the occurrence of disease.
b. make a person or group more vulnerable to disease.
c. never overlap or occur in combination.
d. can all be controlled by prevention.
ANS: B
3. Genetic diseases may be
, a. produced by an abnormality in or mutation of the genetic code in a single gene.
b. caused by several abnormal genes.
c. caused by the abnormal presence or absence of a chromosome or an alteration of
the structure of chromosomes.
d. all of the above.
ANS: D
4. Benign tumors
a. tend to remain encapsulated.
b. infiltrate surrounding tissue.
c. do not compress surrounding tissue or obstruct organs.
d. do not resemble the tissue of origin.
ANS: A
5. Malignant tumors
a. tend to infiltrate other tissue.
b. tend to bleed, ulcerate, and become infected.
c. may spread to distant sites in the body.
d. are all of the above.
ANS: D
6. Which statement is true regarding the TNM (tumor, nodes, metastasis) cancer staging
system?
a. Assesses the size and extent of the spread of the primary tumor.
, b. Is a grading system based on the degree of differentiation of tumor cells.
c. Both a and b are true.
d. Neither a nor b is true.
ANS: A
7. Which of the following correctly states the sequence of an allergic response within the
body most?
a. IgE antibodies enter the body and produce an allergen.
b. The release of histamine sensitizes mast cells and produces symptoms.
c. Exposure to allergen stimulates production of IgE antibodies that can subsequently
trigger symptoms of allergy.
d. Histamine produces mast cells, which stimulate plasma cells.
ANS: C
8. Which of the following most accurately states the orderly steps in making a diagnosis?
a. Medical history, physical examination, diagnostic tests, diagnosis, integration of
results, treatment
b. Medical history, diagnostic tests, physical examination, treatment plan
c. Physical examination, medical history, radiographs, prognosis, integration of all
information
d. Comparison of normals, physical examination, history, treatment plan, prognosis
ANS: A
9. Mechanical and chemical barriers, the inflammatory response, and the immune response
are
, a. risk factors for disease.
b. the combined effects of inheritance and environmental factors.
c. included in the body’s natural defense system against infection.
d. agents that damage DNA.
ANS: C
10. Immune disorders are the result of a breakdown in the body’s defense system that may
generate
a. allergy.
b. autoimmune diseases.
c. immunodeficiency disorders.
d. all of the above.
ANS: D
11. Immunodeficiency disorders result from
a. an exudative response.
b. physical trauma.
c. motor vehicle accidents.
d. a depressed or absent immune response.
ANS: D
12. Which statement(s) is (are) correct regarding autoimmune diseases?
a. The disease allows the immune system to become self-destructive.
b. Many serious diseases have a strong autoimmune component.
