NURS 6521N-26 ADVANCED PHARMACOLOGY INITIAL DISCUSSION WEEK 9 FALL 2021.

NURS6521N-
26:ADVANCED
PHARMACOLOGYINI
TIAL
DI
SCUSSIONWEEK9FALL2021

I
NITI
ALDI
SCUSSI
ONPOST(
Wee
k9)

De
bor
ahL
uce
ro,
RN,
BS,
CVRN-
BC,
FACCN
Ph
armac
oth
era
pyf
orHe
mat
olo
gic
Di
sor
der
s

Si
ckl
eCe
llDi
sea
se

Ac
cor
din
gtot
heNa
tion
alHe
art
,Lu
ng,
andBl
oodI
nst
it
ute

(
NHL
BI)(
201
7),
sic
klec
ell
dis
eas
e(SCD)d
esc
ri
besag
rou
pof

i
nhe
rit
edr
edb
loodc
ell
dis
ord
ers
.SCDi
son
eoft
hemos
t

p
rev
ale
nta
utos
oma
l,r
ece
ssi
veg
ene
ti
cdi
sor
der
sint
heUn
ite
d

St
ate
s.Pe
opl
ewi
thSCDh
avea
bnor
mal
hemog
lob
in,
cal
l
ed

h
emog
lob
inSors
ick
leh
emog
lob
in,
int
hei
rre
dbl
oodc
ell
s,SCD

i
snotc
ont
agi
ous
;iti
sus
ual
l
yin
her
it
ed,
mea
nin
gth
edi
sea
sei
s

,p
ass
edb
yge
nesf
romp
are
ntst
oth
eirc
hil
dre
n.Th
erea
res
ix

f
ormso
fSCDa
ndt
heya
reHe
mog
lob
inSS,
Hemog
lob
inSC,

He
mog
lob
inSB0t
hal
ass
emi
a,He
mog
lob
inSB+t
hal
ass
emi
a,

He
mog
lob
inSD,
andHe
mog
lob
inSE(
NHL
BI,
201
7).
Hemog
lob
in

SS,
thes
ick
lec
ell
ane
mia(
SCA)
,i
sth
emos
tcommona
ndof
ten

t
hemos
tse
ver
eki
ndofSCD.
Hemog
lob
inSCd
ise
asea
nd

h
emog
lob
inSBt
hal
ass
emi
aar
etwoot
herc
ommo
nfor
msofSCD.

Ri
skF
act
ors

Si
ckl
ece
lld
ise
asei
sal
i
fe-
l
ongi
l
lne
ss.
Thes
eve
rit
yoft
he

d
ise
asev
ari
eswi
del
yfr
omp
ers
ont
ope
rson
.Ind
eve
lop
ed

c
oun
tri
esl
i
ket
heUn
ite
dSt
ate
s,t
hel
i
fee
xpe
cta
ncyofap
ers
on

wi
thSCDi
snowa
bou
t40t
o60y
ear
s.Ap
prox
ima
tel
y70
,00
0to

1
00,
000Ame
ric
ansh
aveSCA,
anda
bou
tei
ghtp
erc
entofAf
ri
can

-
Ame
ric
ansc
arr
yth
esi
ckl
ece
llt
rai
t,
whi
chu
nli
ket
hos
ewi
th

,