NURS323FI
NALEXAM FOCUSREVI
EW TOPI
CS
FORSPRI
NG2019OLDMATERIAL(70I
TEMS)
ATLEAST12/
DAY
I
NTRODUCTI ONTONURSINGPHARMACOLOGY
(SAFETY,NURSI
NGPROCESS,
PHARMACOKI NETI
CS,PHARMACODYNAMI
CS)
KNOW ANDUNDERSTANDTHEMECHANI
SM OF
ACTI
ONOFDRUGSONTHI SLIST
1
.Kn
owt
hep
rin
cip
lesofp
har
mac
oki
net
ic
s:a
bsor
pti
on,
dis
tri
but
ion
,me
tab
oli
sma
nd
e
xcr
eti
onPh
arma
cok
ine
ti
csi
showd
rug
smov
eth
rou
ght
heb
ody
/wh
att
heb
odyd
oest
o
t
hed
rug
.Dy
nami
cequ
il
ib
riu
mist
he“
pat
hwa
y”oft
hed
rugt
hrou
ght
heb
odyv
ia
p
har
mac
oki
net
ic
s.
1
.Ab
sor
pti
onf
romwh
eret
heme
dic
ati
oni
sen
ter
edv
iap
ass
iveora
cti
ved
iff
usi
ons
ucha
s
- Bymou
thwou
ldb
eGI
.
- Pa
ren
tal
suc
hasI
V,I
M,SQ,
int
rad
erma
lwou
ldb
eab
sor
bedb
yth
ebl
ood.
- Re
cta
ll
y,v
agi
nal
l
y,s
ubl
i
ngu
al,
ear
s,e
yeswou
ldb
emu
cou
sme
mbr
ane
stot
heb
lood
.
- Top
ica
lwou
ldb
eth
rou
ght
hes
kina
bsor
pti
on.
2
.Di
st
ri
but
iont
oth
eac
ti
ves
it
esu
cha
sge
tti
ngt
oani
nfe
cti
oni
nth
ebod
yi.
e.b
rai
nin
fec
ti
onwou
ld
n
eedal
i
pids
olu
bleme
dic
ati
oni
nor
derf
ori
ttob
edi
st
ri
but
edt
oth
esi
te
.
3
.Me
tab
oli
sm/
Biot
ran
sfor
mat
ionoc
cur
sint
hel
i
vera
ndt
hisi
swh
eret
heme
dic
ati
oni
sbr
oke
n
d
ownt
obee
xcr
ete
dtod
etox
if
yth
ebodyt
ole
ssh
armf
ulc
hemi
cal
s/l
eve
ls.
- F
irs
t-p
asse
ffe
ct:Me
dic
ati
ont
hati
sme
tab
oli
zedb
yth
eli
verd
uri
ngt
hef
ir
stt
imei
tpa
sse
s
(
hen
ce,
fir
st-
pas
s)b
rea
ksd
ownt
hed
ruga
smu
cha
spos
sib
lea
ndt
her
estg
oesi
ntot
heb
ody
.
E
ven
tua
ll
y,i
t’
l
lfi
l
tert
hrou
ght
hel
i
vera
gai
n.
- AST,
ALTl
abst
estf
orl
i
verf
unc
ti
on.
4
.Ex
cre
ti
oni
sth
edr
ugf
ina
ll
yge
tti
ngou
toft
heb
odyp
ret
tymu
chv
iaa
nyt
hin
gth
ebod
yex
cre
tes
, l
i
kes
ali
va,
tea
ts,
etc
.bu
tth
eki
dne
ysa
ret
hema
inme
thodt
oex
cre
ti
on.
Thi
nk:
uri
ned
rugt
est
s.
Gr
r.
2.Knowth
edif
fer
enc
ebetwe
enloa
din
gandmai
nten
ancedose
s
- L
oadi
ngdos
eist
helar
ges
tdoset
oreac
hth
era
peut
iceff
ect–qui
cki
nth
ebod
y.Th
ink
:pa
tie
nt
h
asi
nfe
cti
onora
ndRoc
eph
in1g
misor
der
eda
ndi
spr
esc
ri
beda
nti
bi
oti
cst
oma
int
ain
t
her
ape
uti
cef
fec
tsORE
piPe
ndu
rin
gana
sth
maa
tta
cks
;ju
ston
eoft
hos
ebi
gdos
est
oma
ke
r
eac
hth
era
peu
tice
ffe
ctsQUI
CKL
Y.
- Ma
int
ain
ingt
hel
eve
lsa
tth
era
peu
ticl
eve
ls?
3.Wh ydonur
sesneedt
ok n
owa b
outp h
armacol
ogy
4.5p at
ie
ntri
ght
sofdru
ga dmi
ni
stra
tion
1
. Ri
ghtp
ati
ent–donotwantt
ogivet
owrongp at
ie
nt.
2
.Ri
ghtme
d–d
onotwa
ntt
ogi
vet
hewr
ongp
ati
ent
,ca
nca
usea
dve
rser
eac
ti
ont
owr
ongme
dic
ati
on.
3
.Ri
ghtd
ose–t
oomu
chort
ool
i
ttl
eisn
otb
ene
fic
ial
nort
her
ape
uti
cfort
hep
ati
ent
.
4
.Ri
ghtt
ime–ma
kes
ureme
dic
ati
oni
sad
min
ist
ere
datac
ert
aint
imeb
eca
usei
tus
ual
l
yisa
tth
e
l
owe
rth
era
peu
tice
ffe
ct.
5
.Ri
ghtr
out
e–c
anb
etox
icf
orap
ati
entore
lsemi
ghtn
otb
eab
sor
bed
.
5.Preg
nan
cycate
gori
es(
i.
e.,
C,X,e
tc.
)
- Ca
teg
oryA:
note
sti
ngshowst
hatth
erei
sri
skf
ora
dve
rsee
ffe
ctsi
nla
tert
ri
mes
ter
s.
,- Book
:Ad
equ
ates
tud
iesonp
reg
nan
twome
nha
ven
ode
mon
str
ate
dar
is
ktot
hef
etu
sint
he
f
ir
stt
ri
mes
terofp
reg
nan
cy,
andt
her
eisn
oev
ide
nceofr
is
kinl
ate
rtr
ime
ste
rs.
- Ca
teg
oryB:
Stu
die
sha
veb
eenp
ref
orme
dona
nima
lsa
nds
howa
dve
rsee
ffe
cts
,bu
tno
a
dve
rsee
ffe
ctsi
npr
egn
antwome
n.
- Book
:An
ima
lst
udi
esh
aven
ode
mon
str
ate
dar
is
ktot
hef
etu
sbu
tnoa
dequ
ates
tud
iesi
n
p
reg
nan
cywome
n,o
ran
ima
lst
udi
esh
aves
howna
nad
ver
see
ffe
ct,
buta
dequ
ates
tud
iesi
n
p
reg
nan
twome
nha
ven
otd
emon
str
ate
dar
is
ktot
hef
etu
sdu
rin
gfi
rs
ttr
ime
ste
rofp
reg
nan
cy,
and
t
her
eisn
oev
ide
ncei
nla
tert
ri
mes
ter
s.
- Ca
teg
oryC:
Ani
mal
sha
veb
eent
est
eda
nds
howa
dve
rsee
ffe
ctsb
utt
her
eha
ven
otb
eene
nou
gh
e
vid
enc
eors
tud
iesonp
reg
nan
twome
ntod
ete
rmi
newh
eth
erorn
ott
heywou
lde
xhi
bi
tan
y
a
dve
rsee
ffe
cts
.ORn
ost
udi
esh
aveb
eenp
erf
orme
d–p
eri
od/
Med
ica
tionu
seb
ene
fit
sou
twe
igh
t
hea
dve
rsee
ffe
ct.
- Book
:An
ima
lst
udi
esona
nima
lss
howa
dve
rsee
ffe
ctonf
etu
sbu
tnoa
dequ
ates
tud
iesi
nhu
man
s
t
heb
ene
fit
sfr
omt
heu
seoft
hed
rugi
npr
egn
antwome
nma
ybea
cce
pta
bled
esp
itei
tsp
ote
nti
al
r
is
ks,
ort
her
ear
enoa
nima
lre
prod
uct
ions
tud
iesa
ndn
oad
equ
ates
tud
iesi
nhu
man
s.
- Ca
teg
oryD:
The
rea
res
tudi
est
hath
aves
hownt
her
ear
efe
tal
ri
sks
,bu
tth
ebe
nef
it
sou
twe
igh
t
her
is
ksa
nd/
ora
rea
cce
pta
ble
.
- Book
:Th
eev
ide
nceofh
uma
nfe
tal
ri
sk,
butt
hep
ote
nti
alb
ene
fit
sfr
omt
heu
seoft
hed
rugi
n
p
reg
nan
twome
nma
ybea
cce
pta
bled
esp
itei
tsp
ote
nti
alr
is
ks.
- Ca
teg
oryX:
The
rea
rea
dve
rsee
ffe
ctsa
ndv
eryb
adr
is
ks,
abn
orma
li
ti
esh
aveb
eens
howni
n
b
otha
nima
lsa
ndh
uma
ns.
Ther
is
koft
aki
ngt
hisme
dic
ati
onou
twe
igh
sth
ebe
nef
it
.
- Book
:St
udi
esi
nan
ima
lsorh
uma
nsd
emon
str
atef
eta
lab
nor
mal
i
ti
esora
dve
rser
eac
ti
onr
epor
t
i
ndi
ct
ede
vid
enc
eoff
eta
lri
sk.
Ther
is
kofu
sei
nap
reg
nan
twoma
ncl
ear
lyou
twe
igh
san
y
p
oss
ibl
ebe
nef
it
.
- Al
li
nal
l
,nod
rugi
ssa
feu
nle
ssi
ti
sme
dic
all
yne
ces
sar
yan
dth
ebe
nef
it
sou
twe
ight
her
is
k.
6
.Nu r
si
ngpr
oce
ssanddr
ugadmi
ni
st
rati
on
- As
sessme
nt–ch
ecki
ngt
hepat
ien
twhe
ntheyaref
ir
sta
dmi
tt
edf
ort
hei
rcon
dit
ion
.
- Di
agn
ose
s–n
urs
ingd
iag
nos
ismu
sth
avee
vid
enc
etob
acku
pfr
omt
hea
sse
ssme
nt.
- Pl
an–f
oll
owu
pca
ref
orp
ati
ent
,rxt
hep
ati
entn
eed
s,r
efe
rra
ls.
- I
mpl
eme
nta
tion–Pa
tie
ntn
eed
stof
oll
owt
hrou
gha
ndt
akeRx
.Vi
si
tasn
eed
ed.
- E
val
uat
ion–e
ndg
oal
.
, 7.Wh yiseva
luat
ionphasei
mp or
tant?Whatarethephasesandsomep oss
ibl
e
nursi
ngint
erve
n t
ion
sas s
ociat
edwi t
hthesephaseswhenad min
ist
eri
ngdrugs
.
- Ev
aluat
ionisimport
anttoknowifth
ep at
ienthasanya d
vers
ee f
fectori
fthemedic
ati
on
waseff
e c
ti
v e.?
?
-
8.Pr i
orit
yacti
onsfornur
sestotakeintheeventofame d
icat
ionerr
or
- Asse
sst h
ep ati
ent
,documentadver
see f
fect
s,fi
leaninci
dentr
eport??
9.Si gnsofananaphyl
act
icreact
ion
NALEXAM FOCUSREVI
EW TOPI
CS
FORSPRI
NG2019OLDMATERIAL(70I
TEMS)
ATLEAST12/
DAY
I
NTRODUCTI ONTONURSINGPHARMACOLOGY
(SAFETY,NURSI
NGPROCESS,
PHARMACOKI NETI
CS,PHARMACODYNAMI
CS)
KNOW ANDUNDERSTANDTHEMECHANI
SM OF
ACTI
ONOFDRUGSONTHI SLIST
1
.Kn
owt
hep
rin
cip
lesofp
har
mac
oki
net
ic
s:a
bsor
pti
on,
dis
tri
but
ion
,me
tab
oli
sma
nd
e
xcr
eti
onPh
arma
cok
ine
ti
csi
showd
rug
smov
eth
rou
ght
heb
ody
/wh
att
heb
odyd
oest
o
t
hed
rug
.Dy
nami
cequ
il
ib
riu
mist
he“
pat
hwa
y”oft
hed
rugt
hrou
ght
heb
odyv
ia
p
har
mac
oki
net
ic
s.
1
.Ab
sor
pti
onf
romwh
eret
heme
dic
ati
oni
sen
ter
edv
iap
ass
iveora
cti
ved
iff
usi
ons
ucha
s
- Bymou
thwou
ldb
eGI
.
- Pa
ren
tal
suc
hasI
V,I
M,SQ,
int
rad
erma
lwou
ldb
eab
sor
bedb
yth
ebl
ood.
- Re
cta
ll
y,v
agi
nal
l
y,s
ubl
i
ngu
al,
ear
s,e
yeswou
ldb
emu
cou
sme
mbr
ane
stot
heb
lood
.
- Top
ica
lwou
ldb
eth
rou
ght
hes
kina
bsor
pti
on.
2
.Di
st
ri
but
iont
oth
eac
ti
ves
it
esu
cha
sge
tti
ngt
oani
nfe
cti
oni
nth
ebod
yi.
e.b
rai
nin
fec
ti
onwou
ld
n
eedal
i
pids
olu
bleme
dic
ati
oni
nor
derf
ori
ttob
edi
st
ri
but
edt
oth
esi
te
.
3
.Me
tab
oli
sm/
Biot
ran
sfor
mat
ionoc
cur
sint
hel
i
vera
ndt
hisi
swh
eret
heme
dic
ati
oni
sbr
oke
n
d
ownt
obee
xcr
ete
dtod
etox
if
yth
ebodyt
ole
ssh
armf
ulc
hemi
cal
s/l
eve
ls.
- F
irs
t-p
asse
ffe
ct:Me
dic
ati
ont
hati
sme
tab
oli
zedb
yth
eli
verd
uri
ngt
hef
ir
stt
imei
tpa
sse
s
(
hen
ce,
fir
st-
pas
s)b
rea
ksd
ownt
hed
ruga
smu
cha
spos
sib
lea
ndt
her
estg
oesi
ntot
heb
ody
.
E
ven
tua
ll
y,i
t’
l
lfi
l
tert
hrou
ght
hel
i
vera
gai
n.
- AST,
ALTl
abst
estf
orl
i
verf
unc
ti
on.
4
.Ex
cre
ti
oni
sth
edr
ugf
ina
ll
yge
tti
ngou
toft
heb
odyp
ret
tymu
chv
iaa
nyt
hin
gth
ebod
yex
cre
tes
, l
i
kes
ali
va,
tea
ts,
etc
.bu
tth
eki
dne
ysa
ret
hema
inme
thodt
oex
cre
ti
on.
Thi
nk:
uri
ned
rugt
est
s.
Gr
r.
2.Knowth
edif
fer
enc
ebetwe
enloa
din
gandmai
nten
ancedose
s
- L
oadi
ngdos
eist
helar
ges
tdoset
oreac
hth
era
peut
iceff
ect–qui
cki
nth
ebod
y.Th
ink
:pa
tie
nt
h
asi
nfe
cti
onora
ndRoc
eph
in1g
misor
der
eda
ndi
spr
esc
ri
beda
nti
bi
oti
cst
oma
int
ain
t
her
ape
uti
cef
fec
tsORE
piPe
ndu
rin
gana
sth
maa
tta
cks
;ju
ston
eoft
hos
ebi
gdos
est
oma
ke
r
eac
hth
era
peu
tice
ffe
ctsQUI
CKL
Y.
- Ma
int
ain
ingt
hel
eve
lsa
tth
era
peu
ticl
eve
ls?
3.Wh ydonur
sesneedt
ok n
owa b
outp h
armacol
ogy
4.5p at
ie
ntri
ght
sofdru
ga dmi
ni
stra
tion
1
. Ri
ghtp
ati
ent–donotwantt
ogivet
owrongp at
ie
nt.
2
.Ri
ghtme
d–d
onotwa
ntt
ogi
vet
hewr
ongp
ati
ent
,ca
nca
usea
dve
rser
eac
ti
ont
owr
ongme
dic
ati
on.
3
.Ri
ghtd
ose–t
oomu
chort
ool
i
ttl
eisn
otb
ene
fic
ial
nort
her
ape
uti
cfort
hep
ati
ent
.
4
.Ri
ghtt
ime–ma
kes
ureme
dic
ati
oni
sad
min
ist
ere
datac
ert
aint
imeb
eca
usei
tus
ual
l
yisa
tth
e
l
owe
rth
era
peu
tice
ffe
ct.
5
.Ri
ghtr
out
e–c
anb
etox
icf
orap
ati
entore
lsemi
ghtn
otb
eab
sor
bed
.
5.Preg
nan
cycate
gori
es(
i.
e.,
C,X,e
tc.
)
- Ca
teg
oryA:
note
sti
ngshowst
hatth
erei
sri
skf
ora
dve
rsee
ffe
ctsi
nla
tert
ri
mes
ter
s.
,- Book
:Ad
equ
ates
tud
iesonp
reg
nan
twome
nha
ven
ode
mon
str
ate
dar
is
ktot
hef
etu
sint
he
f
ir
stt
ri
mes
terofp
reg
nan
cy,
andt
her
eisn
oev
ide
nceofr
is
kinl
ate
rtr
ime
ste
rs.
- Ca
teg
oryB:
Stu
die
sha
veb
eenp
ref
orme
dona
nima
lsa
nds
howa
dve
rsee
ffe
cts
,bu
tno
a
dve
rsee
ffe
ctsi
npr
egn
antwome
n.
- Book
:An
ima
lst
udi
esh
aven
ode
mon
str
ate
dar
is
ktot
hef
etu
sbu
tnoa
dequ
ates
tud
iesi
n
p
reg
nan
cywome
n,o
ran
ima
lst
udi
esh
aves
howna
nad
ver
see
ffe
ct,
buta
dequ
ates
tud
iesi
n
p
reg
nan
twome
nha
ven
otd
emon
str
ate
dar
is
ktot
hef
etu
sdu
rin
gfi
rs
ttr
ime
ste
rofp
reg
nan
cy,
and
t
her
eisn
oev
ide
ncei
nla
tert
ri
mes
ter
s.
- Ca
teg
oryC:
Ani
mal
sha
veb
eent
est
eda
nds
howa
dve
rsee
ffe
ctsb
utt
her
eha
ven
otb
eene
nou
gh
e
vid
enc
eors
tud
iesonp
reg
nan
twome
ntod
ete
rmi
newh
eth
erorn
ott
heywou
lde
xhi
bi
tan
y
a
dve
rsee
ffe
cts
.ORn
ost
udi
esh
aveb
eenp
erf
orme
d–p
eri
od/
Med
ica
tionu
seb
ene
fit
sou
twe
igh
t
hea
dve
rsee
ffe
ct.
- Book
:An
ima
lst
udi
esona
nima
lss
howa
dve
rsee
ffe
ctonf
etu
sbu
tnoa
dequ
ates
tud
iesi
nhu
man
s
t
heb
ene
fit
sfr
omt
heu
seoft
hed
rugi
npr
egn
antwome
nma
ybea
cce
pta
bled
esp
itei
tsp
ote
nti
al
r
is
ks,
ort
her
ear
enoa
nima
lre
prod
uct
ions
tud
iesa
ndn
oad
equ
ates
tud
iesi
nhu
man
s.
- Ca
teg
oryD:
The
rea
res
tudi
est
hath
aves
hownt
her
ear
efe
tal
ri
sks
,bu
tth
ebe
nef
it
sou
twe
igh
t
her
is
ksa
nd/
ora
rea
cce
pta
ble
.
- Book
:Th
eev
ide
nceofh
uma
nfe
tal
ri
sk,
butt
hep
ote
nti
alb
ene
fit
sfr
omt
heu
seoft
hed
rugi
n
p
reg
nan
twome
nma
ybea
cce
pta
bled
esp
itei
tsp
ote
nti
alr
is
ks.
- Ca
teg
oryX:
The
rea
rea
dve
rsee
ffe
ctsa
ndv
eryb
adr
is
ks,
abn
orma
li
ti
esh
aveb
eens
howni
n
b
otha
nima
lsa
ndh
uma
ns.
Ther
is
koft
aki
ngt
hisme
dic
ati
onou
twe
igh
sth
ebe
nef
it
.
- Book
:St
udi
esi
nan
ima
lsorh
uma
nsd
emon
str
atef
eta
lab
nor
mal
i
ti
esora
dve
rser
eac
ti
onr
epor
t
i
ndi
ct
ede
vid
enc
eoff
eta
lri
sk.
Ther
is
kofu
sei
nap
reg
nan
twoma
ncl
ear
lyou
twe
igh
san
y
p
oss
ibl
ebe
nef
it
.
- Al
li
nal
l
,nod
rugi
ssa
feu
nle
ssi
ti
sme
dic
all
yne
ces
sar
yan
dth
ebe
nef
it
sou
twe
ight
her
is
k.
6
.Nu r
si
ngpr
oce
ssanddr
ugadmi
ni
st
rati
on
- As
sessme
nt–ch
ecki
ngt
hepat
ien
twhe
ntheyaref
ir
sta
dmi
tt
edf
ort
hei
rcon
dit
ion
.
- Di
agn
ose
s–n
urs
ingd
iag
nos
ismu
sth
avee
vid
enc
etob
acku
pfr
omt
hea
sse
ssme
nt.
- Pl
an–f
oll
owu
pca
ref
orp
ati
ent
,rxt
hep
ati
entn
eed
s,r
efe
rra
ls.
- I
mpl
eme
nta
tion–Pa
tie
ntn
eed
stof
oll
owt
hrou
gha
ndt
akeRx
.Vi
si
tasn
eed
ed.
- E
val
uat
ion–e
ndg
oal
.
, 7.Wh yiseva
luat
ionphasei
mp or
tant?Whatarethephasesandsomep oss
ibl
e
nursi
ngint
erve
n t
ion
sas s
ociat
edwi t
hthesephaseswhenad min
ist
eri
ngdrugs
.
- Ev
aluat
ionisimport
anttoknowifth
ep at
ienthasanya d
vers
ee f
fectori
fthemedic
ati
on
waseff
e c
ti
v e.?
?
-
8.Pr i
orit
yacti
onsfornur
sestotakeintheeventofame d
icat
ionerr
or
- Asse
sst h
ep ati
ent
,documentadver
see f
fect
s,fi
leaninci
dentr
eport??
9.Si gnsofananaphyl
act
icreact
ion
