Golgi Stains
- shows a small percentage of neurons in their entirety
Nissl stains
- shows cell bodies of all neurons (good for gray matter structure)
Myelin stains
- Shows myelin on axons (good for white matter structures)
4 electrical brain recording techniques
- EEG, ECG (EKG), EMG, GSR
EEG records:
- brain waves (electrical activity in the brain)
ECG/EKG (electrocardiogram) records:
- heart activity
EMG records:
- muscle activity
GSR records:
- skin conductance (sweating)
Voltammetry
, - Make chemical measurements in brain
Electrophysiology
- record action potentials in brain
Functional MRI (fMRI)
- examines blood flow/oxygen to the brain area
- gets more than just brain structure
Parkinson's disease
- movement disorder
- tremors, rigidity and slow movement
- loss of neurons in substantia nigra (black substance) in brain
Broca's aphasia
- telegraphic speech
- ex: dog hid table ate bone - lacks the grammar articles
- damage to the left frontal lobe of the cortex
Lesions:
- damage brain, assess behavior, brain function
- toxin produces animal model of Parkinson's disease
- pimple = skin lesion
Voltammetry
- make chemical measure in brain
Electrophysiology
- record action potentials in brain