PHARMACY PHA 3102 quiz.
1. In which of the following phases of clinical testing is the final formulation
usually developed?
a. Phase 3
b. Phase 1
c. Phase 4
d. Phase 2
2. All of the following pharmaceutical items are subject to regulation by cGMP except:
a. Heparin prefilled syringes
b. Implantable insulin infusion pumps
c. Peptides produced by recombinant DNA technology
d. None of the above
3. Toxicological profiles for drugs include all of the following except:
a. Carcinogenicity
b. Drug efficacy
c. Chronic adverse effect
d. Reproduction studies
e. Genotoxicity or mutagenicity studies
4. Which of the following are factors that a pharmacist must consider when determining
a dosage regimen for a specific patient? (Select all that apply)
a. Half-life
b. Clinical state of the patient
c. How the patient will be managed
d. Pharmacodynamics and toxicity of the drug
5. A drug has an elimination t1/2 of 6 hours and follows first-order kinetics. If a single 200-
mg dose is given to an adult male patient by IV bolus injection, what percent of the
dose is lost in 24 hours? (Assuming is first order kinetics)
a. 54
b. 75
c. 85
d. 94
e. 100
6. What is initial concentration of drug if the drug concentration remaining in blood is
7.8 mg/L after 8 hr and half-life is 2.475 hr? (Assume first order kinetics)
a. 20.5
b. 31. 3
c. 52.67
d. 73.26
e. 83.78
7. What is the concentration of drug remaining in systemic circulation after 4 hr, if the
initial concentration is 16.2 mg/L and elimination rate constant (Kel) is 0.2 hr-1?
(Assume the first-order process).
This study source was downloaded by 100000832558064 from CourseHero.com on 03-18-2022 22:09:55 GMT -05:00
https://www.coursehero.com/file/38123946/quizdocx/
1. In which of the following phases of clinical testing is the final formulation
usually developed?
a. Phase 3
b. Phase 1
c. Phase 4
d. Phase 2
2. All of the following pharmaceutical items are subject to regulation by cGMP except:
a. Heparin prefilled syringes
b. Implantable insulin infusion pumps
c. Peptides produced by recombinant DNA technology
d. None of the above
3. Toxicological profiles for drugs include all of the following except:
a. Carcinogenicity
b. Drug efficacy
c. Chronic adverse effect
d. Reproduction studies
e. Genotoxicity or mutagenicity studies
4. Which of the following are factors that a pharmacist must consider when determining
a dosage regimen for a specific patient? (Select all that apply)
a. Half-life
b. Clinical state of the patient
c. How the patient will be managed
d. Pharmacodynamics and toxicity of the drug
5. A drug has an elimination t1/2 of 6 hours and follows first-order kinetics. If a single 200-
mg dose is given to an adult male patient by IV bolus injection, what percent of the
dose is lost in 24 hours? (Assuming is first order kinetics)
a. 54
b. 75
c. 85
d. 94
e. 100
6. What is initial concentration of drug if the drug concentration remaining in blood is
7.8 mg/L after 8 hr and half-life is 2.475 hr? (Assume first order kinetics)
a. 20.5
b. 31. 3
c. 52.67
d. 73.26
e. 83.78
7. What is the concentration of drug remaining in systemic circulation after 4 hr, if the
initial concentration is 16.2 mg/L and elimination rate constant (Kel) is 0.2 hr-1?
(Assume the first-order process).
This study source was downloaded by 100000832558064 from CourseHero.com on 03-18-2022 22:09:55 GMT -05:00
https://www.coursehero.com/file/38123946/quizdocx/
