ICU_Quiz_3
NURS 633 ICU_Quiz_3
ICU Quiz 3: It is made up of multiple choice questions. Topics
included are Topic 6 and 7 readings. The quiz will be timed 30
minutes and will not allow backtracking to any answers after
they have been submitted. It can be taken at any time during
Topic 8. The last date to access is Jan. 18, 2017.
Read chapters 3,5,6,9, and13
Chapter 5
Cholinergic antagonists – agents that bind to cholinoceptor
(muscarinic or nicotinic) and prevent the effects of acetylcholine (Ach)
and other cholinergic agents.
Antimuscarinic agent -
Atropine (isopto atropine)- tertiary amine belladonna alkaloid with
high affinity for muscarinic receptor, binds competitively and
prevents Ach frombinding to those sites – acts centrally and
peripherally – lasts 4 hours – except topically in the eye could last for
days – greatest inhibitory effects are bronchial tissue and secretion of
sweat and saliva
Action:
• eye – blocks muscarinic activity in the eyes resulting in
mydriasis (dilation of the pupil), unresponsiveness to light,
cycloplegia (inability to focus for near vision) – angle-
closure glaucoma, intraocular pressure may rise
• GI – used as an antispasmodic to reduce activity of the GI
tract – Atropine and scopolamine – most potent
antispasmodic drugs – not effective forpeptic ulcer – side
effects reduced saliva secretion, ocular accommodation
and urination
• Cardiovascular – dosage dependent – low doses decreased
heart rate. Effect results from blockade of the M,
receptors on the inhibitory prejunctional neurons – higher
dose can cause a progressive increase in the heart rate by
blocking the M2 receptors of the sinoatrial node
, ICU_Quiz_3
•
Secretions – blocks muscarinic receptors in salivary
glands, producing dryness of the mouth (xerostomia)
Sweat and lacrimal glands are effected
Therapeutic –
• Ophthalmic – topical exerts both mydriatic and cycloplegic
effects – shorter acting (cyclopentolate and tropicamide)
• Antispasmodic – relax gi tract
• Cardiovascular – treat brady cardia
• Antisecretory – blocks upper and lower resp tracts prior to surg
NURS 633 ICU_Quiz_3
ICU Quiz 3: It is made up of multiple choice questions. Topics
included are Topic 6 and 7 readings. The quiz will be timed 30
minutes and will not allow backtracking to any answers after
they have been submitted. It can be taken at any time during
Topic 8. The last date to access is Jan. 18, 2017.
Read chapters 3,5,6,9, and13
Chapter 5
Cholinergic antagonists – agents that bind to cholinoceptor
(muscarinic or nicotinic) and prevent the effects of acetylcholine (Ach)
and other cholinergic agents.
Antimuscarinic agent -
Atropine (isopto atropine)- tertiary amine belladonna alkaloid with
high affinity for muscarinic receptor, binds competitively and
prevents Ach frombinding to those sites – acts centrally and
peripherally – lasts 4 hours – except topically in the eye could last for
days – greatest inhibitory effects are bronchial tissue and secretion of
sweat and saliva
Action:
• eye – blocks muscarinic activity in the eyes resulting in
mydriasis (dilation of the pupil), unresponsiveness to light,
cycloplegia (inability to focus for near vision) – angle-
closure glaucoma, intraocular pressure may rise
• GI – used as an antispasmodic to reduce activity of the GI
tract – Atropine and scopolamine – most potent
antispasmodic drugs – not effective forpeptic ulcer – side
effects reduced saliva secretion, ocular accommodation
and urination
• Cardiovascular – dosage dependent – low doses decreased
heart rate. Effect results from blockade of the M,
receptors on the inhibitory prejunctional neurons – higher
dose can cause a progressive increase in the heart rate by
blocking the M2 receptors of the sinoatrial node
, ICU_Quiz_3
•
Secretions – blocks muscarinic receptors in salivary
glands, producing dryness of the mouth (xerostomia)
Sweat and lacrimal glands are effected
Therapeutic –
• Ophthalmic – topical exerts both mydriatic and cycloplegic
effects – shorter acting (cyclopentolate and tropicamide)
• Antispasmodic – relax gi tract
• Cardiovascular – treat brady cardia
• Antisecretory – blocks upper and lower resp tracts prior to surg
