NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
,NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
MODULE 1
• What are the BON rules and regulations for prescriptive authority for
the advance practice nurse?
• Texas is very restricted
• Describe the pharmacokinetic processes of absorption, distribution,
metabolism and elimination and how differences in these areas affect
drug action.
• Absorption
• Drug’s movement from the site of administration into the
blood.
• Distribution
• Drug’s movement from the blood into the interstitial space
of tissues and from there into cells.
• Metabolism
• Biotransformation is the enzymatically mediated alteration of
drug structure.
• Elimination
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
,NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
• Combination of metabolism and excretion
• Discuss the impact of food on drug absorption, drug metabolism and on
drug toxicity and action—as well as the timing of drug administration.
LIFESPAN
• Hepatic metabolism and GFR increase during pregnancy, dosages of
some drugs may need to be increased.
• Rate of albumin to water decreases
• Third trimester: Renal blood flow is doubled and renal
excretion is accelerated (drugs excreted rapidly)
• Tone and mobility of bowel decrease
• Prolongation of drug effects Total (½ life increases)
Understand stages of development in pregnancy
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
, NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
• Conception: through week 2
• Embryonic period: week 3-week 8
a) Gross malformations can be produced by teratogens
• Fetal period: week 9-delivery
• Understand pregnancy labeling
• 3 categories now
a) Pregnancy, lactation, male & female reproductive
potential
• How do you decrease risk in the infant during breastfeeding?
• Take meds immediately after breastfeeding, avoid drugs that
have long half-lives, choose drugs that tend to be excluded
from milk, avoid drugs that are known to be hazardous.
• How do pediatric patients differ in their response to medications?
• Absorption
a) Oral?
• Neonates: drug remain in the stomach longer
which increases the levels, low acidity can affect
the absorption of acid labile drugs
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
,NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
MODULE 1
• What are the BON rules and regulations for prescriptive authority for
the advance practice nurse?
• Texas is very restricted
• Describe the pharmacokinetic processes of absorption, distribution,
metabolism and elimination and how differences in these areas affect
drug action.
• Absorption
• Drug’s movement from the site of administration into the
blood.
• Distribution
• Drug’s movement from the blood into the interstitial space
of tissues and from there into cells.
• Metabolism
• Biotransformation is the enzymatically mediated alteration of
drug structure.
• Elimination
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
,NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
• Combination of metabolism and excretion
• Discuss the impact of food on drug absorption, drug metabolism and on
drug toxicity and action—as well as the timing of drug administration.
LIFESPAN
• Hepatic metabolism and GFR increase during pregnancy, dosages of
some drugs may need to be increased.
• Rate of albumin to water decreases
• Third trimester: Renal blood flow is doubled and renal
excretion is accelerated (drugs excreted rapidly)
• Tone and mobility of bowel decrease
• Prolongation of drug effects Total (½ life increases)
Understand stages of development in pregnancy
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
, NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
• Conception: through week 2
• Embryonic period: week 3-week 8
a) Gross malformations can be produced by teratogens
• Fetal period: week 9-delivery
• Understand pregnancy labeling
• 3 categories now
a) Pregnancy, lactation, male & female reproductive
potential
• How do you decrease risk in the infant during breastfeeding?
• Take meds immediately after breastfeeding, avoid drugs that
have long half-lives, choose drugs that tend to be excluded
from milk, avoid drugs that are known to be hazardous.
• How do pediatric patients differ in their response to medications?
• Absorption
a) Oral?
• Neonates: drug remain in the stomach longer
which increases the levels, low acidity can affect
the absorption of acid labile drugs
NURS 5334 PHARM STUDY GUIDE
QUIZ 1 LATEST UPDATE BEST
EXAM SOUTION GRADED A+
