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Half-life- time required for the concentration or amount of drug in
the body to be reduced by one-half
handwritten orders- A prescription for medications/ referrals
Application of Pharmacology in Patient care= (1) pre-
administration assessment, (2) dosage and administration, (3)
evaluating and promoting therapeutic effects, (4) minimizing
adverse effects, (5) minimizing adverse interactions, (6)
making PRN decisions
Receptor binding Binding of a ligand to a receptor changes its
shape or activity, allowing it to transmit a signal or directly
produce a change inside of the cell. Stages of signal transduction:
ligand-receptor binding, signal relay, response.
Pharmacokinetics -Absorption-distribution-metabolism-
Excretion-- how a body processes a drug
Pharmacodynamics- what a drug does to the body)
Adverse effect/side effect and expected and unexpected.
Teratogenic effect- are drugs, chemicals, or even infections that
can cause abnormal fetal development
Paradoxical effect-not the intended effect (lavender to
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calm but it makes em crazy)
Cholinergic vs Anticholinergic side effects
• Anticholinergic
o Can’t see, can’t pee, can’t spit, can’t shit
• Cholinergic
o S-alivation
o L-acrimation (tears)
o U-rination
o D-
efication Dosage
Calculations
Medication Rights
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• Right dose, person, time, med, route
Nursing Process: Assessment, diagnosis, planning,
implementation, and evaluation. (ADPIE)
Terminology: EPS, Tardive dyskinesia, Akathisia, dystonia,
parkinsonism
• Extrapyramidal symptoms. Weird mouth
movements. Fidgeting. Involuntary muscle
contraction.
• Parkinsonism is any condition that causes a combination
of the movement abnormalities seen in Parkinson's disease
— such as tremor, slow movement, impaired speech, or
muscle toughness — especially resulting from the loss of
dopamine-containing nerve cells. AKA EPS
Carvidopa/levodopa (Sinemet)- *Parkinson Med*
- Know action (what does it do), Nurse recommendation for
patients who develop SE/AE of medication, Anticipated SE/AE
of this medication, Pt education
• BASICALLY- levodopa turns into dopamine,
increasing dopamine in the brain and balancing
dopamine and acetylcholine. Carbidopa helps
the body absorb levodopa which makes it more
available to the CNS. C/L=Dopamine agonist
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