MSN 572 Pharmacology combine complete solution latest 2022/2023

MSN 572 Pharmacology combine complete solution


1. Why are most statins recommended to be taken in the evening?
 Can cause insomnia
 Decreases stomach upset
 Cholesterol synthesis increases during the night 
 Cholesterol synthesis decreases during the night

2. What is the mechanism of action of ezetimibe?

 It inhibits the absorption of bile, thus causing the liver to produce bile
from cholesterol.*
 It decreases the adhesion of cholesterol on the arterial walls.
 It inhibits absorption of dietary and biliary cholesterol in the small
intestine.
 (option cutoff)

3. Which of the following is not an expected adverse effect of Niacin?
 Arthralgias
 Hyperglycemia
 Itching
 Flushing

4. Which adverse effects would you monitor for a patient receiving a statin
to manage cholesterol levels. Select all that apply.
 Gallstone development
 Increased serum transaminase levels
 Unexplained muscle pain or tenderness *
 Nonalcoholic fatty liver disease *
 Elevated creatinine kinase (CK) level with muscle pain *

5. Which of the following drug classes should be avoided in peptic ulcer
disease?
 Avoid diuretics
 Avoid NSAIDS
 Avoid proton pump inhibitors
 Avoid antibiotics

,MSN 572 Pharmacology combine complete solution


6. Which of the following groups of antibiotics is notable for side effects such
as nephrotoxicity and ototoxicity?
 Cephalosporins
 Beta-lactams
 Aminoglycoside
 Tetracyclines

7. Which of the following is most likely an intervention for otitis media?
 Corticosteroids
 Aspirin
 Immunoglobulins
 Amoxicillin

8. Which of the following medications is a fluoroquinolone antibiotic?
 Penicillin
 Azithromycin
 Amikacin
 Ciprofloxacin

9. Which of the following best classifieds aminoglycosides, macrolides, and
clindamycin?
 mycolic acid synthesis inhibitors
 protein synthesis inhibitors 
 cell wall inhibitors
 folic acid synthesis inhibitors



10. Which of the following groups of antibiotics binds to the 50S subunit of
the bacterial ribosome and includes drugs such as erythromycin and
azithromycin?
 macrolides
 fluoroquinolones
 aminoglycosides
 tetracyclines

,MSN 572 Pharmacology combine complete solution


11. Which of the following groups of people are at risk for early
hypertension?
 African American
 Adolescents or young adults
 Mexican American Culture
 Old females

12. Which of the following drug treatment strategies is associated with
peptic ulcer disease?
 Opioids
 Two antibiotics 
 Corticosteroids
 Hormonal therapy

13. Which of the following medications or drug classes is commonly
indicated for managing gestational hypertension?
 Spironolactone (Aldactone)
 Loop diuretics
 Calcium channel blockers 
 Dobutamine
 Calcium gluconate

14. Which antibiotic class disrupts folate metabolism in bacteria and is often
combined with trimethoprim?
 cephalosporins
 fluoroquinolones
 Aminoglycosides
 Sulfonamides
 macrolides

15. Convert 15 lbs 8 oz to kilograms. Round to the nearest 100th.
 7.00 
 34.10
 33.00
 7.03

, MSN 572 Pharmacology combine complete solution


16. A patient receiving intravenous gentamicin has a toxic serum drug level.
The prescriber confirms that the dosing is correct. Which possible cause of
the situation will the provider explore?
 Whether patient is taking a medication that binds to serum albumin
 Whether a loading dose was administered
 If the ordered dose frequency is longer than the gentamicin half-life
 If the drug was completely dissolved in the IV solution

17. The therapeutic index is a measure of drug:
 Absorption rate
 Safety profile 
 Bioavailability status
 Effectiveness

18. Which science provides primary healthcare providers the opportunity to
individualize drug therapy based on a patient's genetic makeup?
 Pharmacogenetics
 Pharmacogenomics *
 Pharmacodynamics
 Pharmacokinetics

19. Which of the following is the most appropriate choice to describe age
associated changes that can affect pharmacokinetics in older patients?
 Increase in total body water
 Decrease in creatinine clearance
 (option cutoff)
 (option cutoff)

20. Drugs that use CYP 3A4 enzymes for metabolism may:
 None of the answers are correct
 Induce the metabolism of another drug
 Inhibit the metabolism of another drug *
 Both induce and inhibit the metabolism of another drug. CORRECT

21. An example of a first-dose reaction that may occur includes:
 Orthostatic hypotension that does not occur with repeated doses
 Hemolytic anemia from Ceftriaxone use
 Contact dermatitis from neomycin use * CORRECT
 Purple glove syndrome with phenytoin use