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HYPERLIPIDEMIA
CLINICAL PRACTICE GUIDELINE ASSIGNMENT
HELEN GAMADA
NR511: DIFFERENTIAL DIAGNOSIS
DR. MARGARET SMITH
AUGUST 2019
,INCIDENCE AND PREVALENCE IN U.S.
In 2015-2016- > 12% of adults had total cholesterol >240 mg/d
18% had HDL level < 40 mg/dL
95 million U.S. adults age > 20 had total cholesterol level > 200
mg/dL
Nearly 1 in 3 Americans have high cholesterol
29 million total cholesterol levels > 240 mg/dL
7% adolescents age 6-19 had high total cholesterol
("High Cholesterol Facts, " 2019)
, PATHOPHYSIOLOGY
Cholesterol types
Low-Density Lipoprotein (LDL)
Very Low-Density Lipoprotein
High-Density Lipoprotein (HDL)
Is an essential lipophilic molecule for human life
has many roles for the normal function of cells
Is an essential component of the cell membrane
Is a precursor molecule in vitamin D synthesis, steroid hormones
sex hormones
Is a constituent of bile salt-used in the digestion of fat-soluble
vitamins A,D, E, and K
("Hypercholesterolemia (high blood cholesterol) information | myVMC," n.d.).