NR511_wk_7_CPG_PPT__2_.pptx

CHOLESTEROL
HYPERLIPIDEMIA
CLINICAL PRACTICE GUIDELINE ASSIGNMENT
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HELEN GAMADA
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NR511:DIFFERENTIALDIAGNOSIS
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DR. MARGARET SMITH
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AUGUST2019 i

,INCIDENCE AND PREVALENCE IN U.S. i i i i




➢In2015-2016- > 12% of adults had total cholesterol >240 mg/dL
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➢18% had HDL level < 40 mg/dL
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➢95million U.S. adults age > 20 had total cholesterol level > 200
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mg/dL
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➢Nearly 1 in 3 Americans have high cholesterol
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➢29million total cholesterol levels > 240 mg/dL
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➢7%adolescents age 6-19 had high total cholesterol
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("High Cholesterol Facts, " 2019)
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, PATHOPHYSIOLOGY
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Cholesterol types i




Low-Density Lipoprotein (LDL) i i




Very Low-Density Lipoprotein
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High-Density Lipoprotein (HDL)
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Is an essential lipophilic molecule for human life
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has many roles for the normal function of cellsi i i i i i i i




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Is an essential component of the cell membrane
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Is a precursor molecule in vitamin D synthesis, steroid hormones, sex
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hormones
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Is a constituent of bile salt-used in the digestion of fat-soluble vitami
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A,D, E, and K
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("Hypercholesterolemia (high blood cholesterol) information | myVMC," n.d.).
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