Chapter 7 Innate Immunity Questions
I I I I
1. 1.ID: I 18662104380
Which I of Ithe Ifollowing I is I an I example I of I a I physical I barrier?
A. Antibacterial Ifatty Iacids
B. Lysozymes Iin Itears
C. Epithelial I cells I Correct
Epithelial Icells Iform Itight Ijunctions Ithat Iare Ia Iphysical Ibarrier Ito Ientry Ifor Iorganisms.
ISebaceous I glands I in I the I skin I secrete I antibacterial I and I antifungal I fatty I acids. I Earwax
Iand Ilysozymes Iin Itears Iare Iexamples Iof Ibiochemical Isecretions Ithat Itrap Ipotential
Idisease-causing Imicroorganisms.
D. Earwax
Awarded I 0.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
2. 2.ID: I 18662104374
Which I statement I is I true I regarding I the I inflammatory I response?
A. Inflammatory Iresponse Iis Ithe Ithird Iline Iof Idefense.
B. Inflammatory I response I relies I on I cellular I components I only
C. Inflammatory I response I generates I a I nonspecific I response. I CorrectIThe
Iinflammatory Iresponse Iis I the Isecond Iline Iof Idefense. IIt Ioccurs Iat Ithe Isite Iof Itissue
I injury Iand I generates I a I nonspecific Iresponse I that I involves I cellular I and Ichemical
I components. I The I inflammatory I response I occurs I in I tissues I with I a I blood Isupply
I(vascularized).
D. Inflammatory I response I occurs I in I nonvascular
I tissue.IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
3. 3.ID: I 18662104392
Which I complement I factor I is I considered I an I anaphylatoxin?
A. C3a I Correct
C3a, I C5a, I and I C4a I are I anaphylatoxins. I They I can I induce I the I rapid I degranulation I of
Imast Icells Iand Ithe Irelease Iof Ihistamine.
B. C1
C. C7
D. C9
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
4. 4.ID: I 18662104398
Which Ireceptor Iis Iexpressed Ion Imacrophages Iand Ifacilitates Irecognition IandIphagocytosis
Iof Ibacterial Ipathogens?
A. Complement I receptors
B. Scavenger Ireceptors ICorrect
The I scavenger I receptors I are I primarily I expressed I on I macrophages I and I facilitate
Irecognition I and I phagocytosis I of I bacterial I pathogens. I Complement I receptors
Irecognize I a I variety I of Ifragments I produced I through I activation I of I the I complement
Isystem. IToll-like Ireceptors Iare Iexpressed Ion Ithe Isurface Iof Icells, Iincluding Iepithelial,
Imast, I neutrophils, I macrophages, I dendritic I cells, Iand I lymphocytes. I They Irecognize
, pathogen-associated I molecular I patterns I or Istressed I host I cells. IPattern I recognition
Ireceptors I recognize I patterns I of Iinfectious Imolecules. I These I receptors I are Ifound Ion
Icells Iinvolved Iin Iinnate Iresistance.
C. Toll-like Ireceptors
D. Pattern Irecognition Ireceptors
IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
5. 5.ID: I 18662104390
Which I statement I regarding I mast I cells I is I true?
A. Histamine I causes I vasoconstriction.
B. Mast I cells I are I found I only I in I blood I vessels.
C. Snake I bites, I bee I venoms, I and I toxins I may I cause I activation. I Correct IA Inumber Iof
Ithings Icause Ithe Iactivation I of Imast Icells, Iincluding Iphysical Iinjury, Ichemical I agents
I (including I toxins, I bee I venom, I and I snake I bites), I immunologic Imeans, I and
I activation I of I an I inflammatory I response. I Histamine I is I released I from I mastIcells I and
I causes I vasodilation. I Mast I cells I are I found I in I loose I connective I tissue I close I toIblood
Ivessels. IMast Icells Iare Iinvolved Iin Iinitiating Imany Iallergic Ireactions.
D. Mast Icells Iare Inot Iinvolved Iin Iallergic Ireactions.
IAwarded I1.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
6. 6.ID: I 18662104394
Which Iterm Idescribes Ian Iacidic Isulfur-containing Ilipid Ithat Iproduces Ieffects Isimilar Ito
Ihistamine?
A. Leukotriene ICorrect
Leukotrienes Iact I similar I to I histamine I and Icause Ismooth I muscle I contraction,
Iincreased I vascular I permeability, I and I chemotaxis. I Prostaglandins I cause I increased
Ivascular I permeability, I chemotaxis, I and I pain. IAdhesion I molecules I increase I the
Istickiness I between I cells. I Phagocyte I cells I ingest I and I dispose I of I foreign I material.
B. Prostaglandin
C. Adhesion I molecule
D. Phagocyte
Awarded I 0.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
7. 7.ID: I 18662104376
Which I statement I is I true I regarding I neutrophils?
A. Neutrophils Iare Iagranular.
B. Neutrophils I are I the I predominant I phagocytes I of I earlyIinflammation.
I Correct
Neutrophils Iare I the Ipredominant Iphagocytes Iof Iearly Iinflammation. IThey Iarrive
Ibefore I lymphocytes I and I macrophages. I Monocytes I are I the I largest I blood I cells I and
I areIgranular.
C. Neutrophils Iare Ithe Ilargest Iblood Icells.
D. Neutrophils Ienter Ithe Isite Iof Iinjury Iafter Ilymphocytes IandImacrophages.
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
8. 8.ID: I 18662104700
, What Ibiochemical Imessenger Iis Iproduced Iby Imacrophages Iand Ilymphocytes IinIresponse
Ito Ia Ibacterial Ipathogen?
A. Interleukins ICorrect
Interleukins I are I biochemical I messengers Iproduced I by I macrophages I and
Ilymphocytes I in Iresponse Ito Ia Ibacterial Ipathogen. IInterferons Iprimarily Iprotect
Iagainst I viral I infections. I Chemokines I induce I leukocyte I chemotaxis. I Tumor I necrosis
Ifactor, Iproduced Iby Imacrophages I and I lymphocytes, Iinduces I a I multitude I of
Iproinflammatory Ieffects Iincluding Ithe Ienhancement Iof Iendothelial Icell Iadhesion.
B. Interferons
C. Chemokines
D. Tumor Inecrosis Ifactor
IAwarded I 0.0 Ipoints I out I of I1.0 I possible Ipoints.
9. 9.ID: I 18662104384
Chronic I inflammation I is I characterized I by I a(an)
A. lack I of I giant I cells.
B. absence I of I exudate.
C. dense I infiltrate I of I lymphocytes I and I macrophages. I Correct IChronic
I inflammation I is I characterized I by I a Idense I infiltrate I of I lymphocytes I and
Imacrophages. IGiant Icells Iare Imultinucleated Icells Ithat Iare Iformed I by Ifused
macrophages Iduring Igranuloma Iformation. IChronic Iinflammation Ioften Iresults Iin Ipus
Iformation, Ipurulent Idischarge, Iand Iincomplete Iwound Ihealing. IChronic Iinflammation
Iof Iany Icause Ilasts Ilonger Ithan I2 Iweeks.
D. inflammation Ithat Ilasts Iless Ithan I2 Iweeks.
IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
10. 10.ID: I 18662104386
Which I are I not I natural I barriers?
A. Physical
B. Resistance ICorrect
Resistance I is I a I means I by Iwhich I the I body I may Iavoid I being I infected, I but I it Iis I not I a
Inatural Ibarrier. IThe Inatural Ibarriers Iinclude Iphysical, Ibiochemical, Iand Imechanical,Ias
Iwell Ias Iinflammation Iat Ithe Ibody’s Isurfaces.
C. Biochemical
D. Mechanical
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
11. 11.ID: I 18662104388
Which I characteristics I are I observable I of Ivascular I injury I and I inflammation? I (Select I all
Ithat Iapply.)
A. Redness I Correct
B. Coolness I to I the I touch
C. Warmth I to I the I touch I Correct
D. Increased Iswelling ICorrect
E. Pain ICorrect
I I I I
1. 1.ID: I 18662104380
Which I of Ithe Ifollowing I is I an I example I of I a I physical I barrier?
A. Antibacterial Ifatty Iacids
B. Lysozymes Iin Itears
C. Epithelial I cells I Correct
Epithelial Icells Iform Itight Ijunctions Ithat Iare Ia Iphysical Ibarrier Ito Ientry Ifor Iorganisms.
ISebaceous I glands I in I the I skin I secrete I antibacterial I and I antifungal I fatty I acids. I Earwax
Iand Ilysozymes Iin Itears Iare Iexamples Iof Ibiochemical Isecretions Ithat Itrap Ipotential
Idisease-causing Imicroorganisms.
D. Earwax
Awarded I 0.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
2. 2.ID: I 18662104374
Which I statement I is I true I regarding I the I inflammatory I response?
A. Inflammatory Iresponse Iis Ithe Ithird Iline Iof Idefense.
B. Inflammatory I response I relies I on I cellular I components I only
C. Inflammatory I response I generates I a I nonspecific I response. I CorrectIThe
Iinflammatory Iresponse Iis I the Isecond Iline Iof Idefense. IIt Ioccurs Iat Ithe Isite Iof Itissue
I injury Iand I generates I a I nonspecific Iresponse I that I involves I cellular I and Ichemical
I components. I The I inflammatory I response I occurs I in I tissues I with I a I blood Isupply
I(vascularized).
D. Inflammatory I response I occurs I in I nonvascular
I tissue.IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
3. 3.ID: I 18662104392
Which I complement I factor I is I considered I an I anaphylatoxin?
A. C3a I Correct
C3a, I C5a, I and I C4a I are I anaphylatoxins. I They I can I induce I the I rapid I degranulation I of
Imast Icells Iand Ithe Irelease Iof Ihistamine.
B. C1
C. C7
D. C9
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
4. 4.ID: I 18662104398
Which Ireceptor Iis Iexpressed Ion Imacrophages Iand Ifacilitates Irecognition IandIphagocytosis
Iof Ibacterial Ipathogens?
A. Complement I receptors
B. Scavenger Ireceptors ICorrect
The I scavenger I receptors I are I primarily I expressed I on I macrophages I and I facilitate
Irecognition I and I phagocytosis I of I bacterial I pathogens. I Complement I receptors
Irecognize I a I variety I of Ifragments I produced I through I activation I of I the I complement
Isystem. IToll-like Ireceptors Iare Iexpressed Ion Ithe Isurface Iof Icells, Iincluding Iepithelial,
Imast, I neutrophils, I macrophages, I dendritic I cells, Iand I lymphocytes. I They Irecognize
, pathogen-associated I molecular I patterns I or Istressed I host I cells. IPattern I recognition
Ireceptors I recognize I patterns I of Iinfectious Imolecules. I These I receptors I are Ifound Ion
Icells Iinvolved Iin Iinnate Iresistance.
C. Toll-like Ireceptors
D. Pattern Irecognition Ireceptors
IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
5. 5.ID: I 18662104390
Which I statement I regarding I mast I cells I is I true?
A. Histamine I causes I vasoconstriction.
B. Mast I cells I are I found I only I in I blood I vessels.
C. Snake I bites, I bee I venoms, I and I toxins I may I cause I activation. I Correct IA Inumber Iof
Ithings Icause Ithe Iactivation I of Imast Icells, Iincluding Iphysical Iinjury, Ichemical I agents
I (including I toxins, I bee I venom, I and I snake I bites), I immunologic Imeans, I and
I activation I of I an I inflammatory I response. I Histamine I is I released I from I mastIcells I and
I causes I vasodilation. I Mast I cells I are I found I in I loose I connective I tissue I close I toIblood
Ivessels. IMast Icells Iare Iinvolved Iin Iinitiating Imany Iallergic Ireactions.
D. Mast Icells Iare Inot Iinvolved Iin Iallergic Ireactions.
IAwarded I1.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
6. 6.ID: I 18662104394
Which Iterm Idescribes Ian Iacidic Isulfur-containing Ilipid Ithat Iproduces Ieffects Isimilar Ito
Ihistamine?
A. Leukotriene ICorrect
Leukotrienes Iact I similar I to I histamine I and Icause Ismooth I muscle I contraction,
Iincreased I vascular I permeability, I and I chemotaxis. I Prostaglandins I cause I increased
Ivascular I permeability, I chemotaxis, I and I pain. IAdhesion I molecules I increase I the
Istickiness I between I cells. I Phagocyte I cells I ingest I and I dispose I of I foreign I material.
B. Prostaglandin
C. Adhesion I molecule
D. Phagocyte
Awarded I 0.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
7. 7.ID: I 18662104376
Which I statement I is I true I regarding I neutrophils?
A. Neutrophils Iare Iagranular.
B. Neutrophils I are I the I predominant I phagocytes I of I earlyIinflammation.
I Correct
Neutrophils Iare I the Ipredominant Iphagocytes Iof Iearly Iinflammation. IThey Iarrive
Ibefore I lymphocytes I and I macrophages. I Monocytes I are I the I largest I blood I cells I and
I areIgranular.
C. Neutrophils Iare Ithe Ilargest Iblood Icells.
D. Neutrophils Ienter Ithe Isite Iof Iinjury Iafter Ilymphocytes IandImacrophages.
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
8. 8.ID: I 18662104700
, What Ibiochemical Imessenger Iis Iproduced Iby Imacrophages Iand Ilymphocytes IinIresponse
Ito Ia Ibacterial Ipathogen?
A. Interleukins ICorrect
Interleukins I are I biochemical I messengers Iproduced I by I macrophages I and
Ilymphocytes I in Iresponse Ito Ia Ibacterial Ipathogen. IInterferons Iprimarily Iprotect
Iagainst I viral I infections. I Chemokines I induce I leukocyte I chemotaxis. I Tumor I necrosis
Ifactor, Iproduced Iby Imacrophages I and I lymphocytes, Iinduces I a I multitude I of
Iproinflammatory Ieffects Iincluding Ithe Ienhancement Iof Iendothelial Icell Iadhesion.
B. Interferons
C. Chemokines
D. Tumor Inecrosis Ifactor
IAwarded I 0.0 Ipoints I out I of I1.0 I possible Ipoints.
9. 9.ID: I 18662104384
Chronic I inflammation I is I characterized I by I a(an)
A. lack I of I giant I cells.
B. absence I of I exudate.
C. dense I infiltrate I of I lymphocytes I and I macrophages. I Correct IChronic
I inflammation I is I characterized I by I a Idense I infiltrate I of I lymphocytes I and
Imacrophages. IGiant Icells Iare Imultinucleated Icells Ithat Iare Iformed I by Ifused
macrophages Iduring Igranuloma Iformation. IChronic Iinflammation Ioften Iresults Iin Ipus
Iformation, Ipurulent Idischarge, Iand Iincomplete Iwound Ihealing. IChronic Iinflammation
Iof Iany Icause Ilasts Ilonger Ithan I2 Iweeks.
D. inflammation Ithat Ilasts Iless Ithan I2 Iweeks.
IAwarded I0.0 Ipoints Iout Iof I1.0 Ipossible Ipoints.
10. 10.ID: I 18662104386
Which I are I not I natural I barriers?
A. Physical
B. Resistance ICorrect
Resistance I is I a I means I by Iwhich I the I body I may Iavoid I being I infected, I but I it Iis I not I a
Inatural Ibarrier. IThe Inatural Ibarriers Iinclude Iphysical, Ibiochemical, Iand Imechanical,Ias
Iwell Ias Iinflammation Iat Ithe Ibody’s Isurfaces.
C. Biochemical
D. Mechanical
Awarded I 1.0 Ipoints Iout I of I1.0 Ipossible Ipoints.
11. 11.ID: I 18662104388
Which I characteristics I are I observable I of Ivascular I injury I and I inflammation? I (Select I all
Ithat Iapply.)
A. Redness I Correct
B. Coolness I to I the I touch
C. Warmth I to I the I touch I Correct
D. Increased Iswelling ICorrect
E. Pain ICorrect
