Agonists ______ the release of neurotransmitters, while antagonists ______ the release of
neurotransmitters
- activate; prevent
What does acetylcholine activate?
- skeletal muscles
What does norepinephrine affect?
- emotional arousal, regulation of hunger, alertness, etc.
What does dopamine affect?
- motor movements
What does serotonin affect?
- mood states and emotion, sleep regulation
What is the neurotransmitter that is mimicked by opiates?
- endorphins
Endorphins play a major role in what?
- pain relief and physical experiences of pleasure
GABA and glutamate are ______ and ______ neurotransmitters
- inhibitory and excitatory
,What substances act on GABA?
- tranquilizers and alcohol
Glutamate is indicated in what processes? And what drugs act as glutamate?
- learning and memory; hallucinogenic drugs
The central nervous system includes what?
- brain and spinal cord
The peripheral nervous system includes what?
- sensory and motor nerves and autonomic nervous system
The autonomic nervous system is divided into what two branches?
sympathetic and parasympathetic
The sympathetic branch of the nervous system produces what?
- emotional arousal
What does the parasympathetic branch control?
- the body when at rest
What disease is caused by irregular production of dopamine?
- parkinson's
What does an electroencephalography (EEG) involve?
- measuring the brain's electrical activity through the scalp
How does a computerized axial tomography (CT scan) work?
, - passes x-rays through the head to get a 3D image of the brain
What does a positron-emission tomography (PET) involve?
- injecting weak radio isotopes into the brain
How does a magnetic resonance imaging (MRI) work?
- a strong magnetic field is passed through a person's head
Pharmacokinetics is the branch of pharmacology that concerns the what?
- absorption, distribution, biotransformation, and excretion of drugs
Pharmacodynamics is the branch of pharmacology that concerns the what?
- biochemical and physiological effects of drugs and their mechanism of action
Drug dose is computed according to the recipient's what?
- body weight
What is the standard way of expressing dose?
- milligrams of drug per kilogram of body weight
What is the route of administration?
- site where drug is taken, or how it is taken
Administration of drugs through the mouth
- oral administration
Injecting drugs under the skin