BioChem C785 Study Guide PA Questions And Answers( Complete Solution Rated A)

BioChem C785 study guide PA
Complementary DNA and/or RNA molecules pair with each other by hydrogen bonding
during replication, transcription, or translation. Which of the following pairs of molecules
are complementary? (Select all that apply) –

tRNA and mRNA
mRNA and template DNA

During DNA replication the parent strands ______ and DNA polymerase______. -
separate, creates the new DNA strands

The following sequence is one strand of the DNA that makes up the SNCA gene that
codes for alpha-synuclein, a protein found in the brain. 5' ATGCGGTGACGG 3' Which
of the following is the complementary second DNA strand? –

5' CCGTCACCGCAT 3'

Assume you start with one copy of target DNA. How many copies of DNA will be made
after 4 rounds of PCR (assume 100% reaction efficiency)? –

16

What are the necessary ingredients for a PCR reaction? –

dNTPs; thermostable DNA polymerase; DNA primers; double-stranded DNA

A frameshift mutation changed this sequence 5' AAC GCT TAG 3' to which of the
following? –

3' GAT TCG CA 5'

Which choice represents a silent mutation for this sequence: 5' GGU UGC ACU 3'? –

5' GGU UGC ACA 3'

Beta thalassemia is a disease that causes low levels of hemoglobin. To inherit this
autosomal disease, an individual must receive two mutant alleles. Which of the following
likely represents the chromosome pairs of a healthy parent who has a child with beta
thalassemia?

(The yellow band represents the mutant allele and the green band represents the
normal allele.) * - Option 3- The chromosomes of a healthy parent who has a child
with beta thalassemia must be a carrier of the disease, i.e. the parent must have
one copy of the (dominant) normal allele and one copy of the (recessive) mutant
allele.

, Your black dog and your friend's white dog have puppies. If inheritance of coat
color is co-dominant, the coat color of the puppies will be ________________, the
color will be _______________ if incompletely dominant, and it will be
_______________ if it is complete dominant - Black-and-white spotted, gray, black

Freidreich's ataxia is an autosomal recessive disorder that results from multiple GAA
insertions into the FXN gene. Which of the following best illustrates the inheritance
pattern of Freidreich's ataxia in a family with the disease? –

None of these pedigrees are consistent with an autosomal recessive pattern.

The pedigree chart for Option 3 shows evidence of carriers, and both males and
females have Friedrich's ataxia in this chart. These properties of the chart
indicate that it is for an autosomal recessive disease.

Increased IGF2 expression is associated with many types of cancer. Studies have
shown that when mothers take folic acid before conception, children have increased
methylation of this gene. Which of the following is the best explanation for how this
increased methylation could be beneficial? –

The increased methylation decreases the space between nucleosomes,
decreasing the expression of the IGF2 gene.

Which of the following sequences represents a coding strand of DNA that leads to the
production of the following polypeptide chain:

Tyr Cys Val - 5' TAC TGT GTA 3'

Which of the following accurately compares DNA mismatch repair and nucleotide
excision repair? –

Both processes involve recognition of the section requiring repair, removal of
this section, replacement of the bases with DNA polymerase, and ligation.

Which of the following best describes the role of nonhomologous end joining? –

When there are double stranded breaks, this process joins the ends of the DNA
together to fix the break.

The _____ and _____ are common to all amino acids but the ______ is unique to
each amino acid. - Carboxyl group, amino group, R group

Which of the following amino acids would form an ionic bond with lysine? –