Question
Question 1.1. A 40-year-old woman who experiences severe seasonal allergies has been
referred by her family physician to an allergist for weekly allergy injections. The woman is
confused as to why repeated exposure to substances that set off her allergies would ultimately
benefit her. Which of the following phenomena best captures the rationale for allergy
desensitization therapy? (Points : 3)
Repeated exposure to offending allergens binds the basophils and mast cells that mediate the
allergic response.
Exposure to allergens in large, regular quantities overwhelms the IgE antibodies that mediate
the allergic response.
Repeated exposure stimulates adrenal production of epinephrine, mitigating the allergic
response.
Injections of allergens simulate production of IgG, which blocks antigens from combining
with IgE.
Question 2.2. A 14-year-old boy has been diagnosed with infectious mononucleosis. Which
of the following pathophysiological phenomena is most responsible for his symptoms?
(Points : 3)
The Epstein-Barr virus (EBV) is lysing many of the boy's neutrophils.
Viruses are killing some of his B cells and becoming incorporated into the genomes of others.
The EBV inhibits the maturation of white cells within his peripheral lymph nodes.