AQA
A-Level
BIOLOGY
3.2 | b Immunity
Cell Recognition and Immune system
Time allowed
50 minutes
QUESTION PAPER
Score Percentage
/40 %
4.1 | CELL BIOLOGY | QUESTION PAPER 1 1
, Malaria is a disease caused by parasites belonging to the genus Plasmodium. Two species
that cause malaria are Plasmodium falciparum and Plasmodium vivax.
A test strip that uses monoclonal antibodies can be used to determine whether a person is
infected by Plasmodium. It can also be used to find which species of Plasmodium they are
infected by.
• A sample of a person’s blood is mixed with a solution containing an antibody, A, that
binds to a protein found in both species of Plasmodium. This antibody has a
coloured dye attached.
• A test strip is then put into the mixture. The mixture moves up the test strip by
capillary action to an absorbent pad.
• Three other antibodies, B, C and D are attached to the test strip. The position of
these antibodies and what they bind to is shown in Figure 1.
Figure 1
(a) Explain why antibody A attaches only to the protein found in species of
Plasmodium.
........................................................................................................................
........................................................................................................................
........................................................................................................................
........................................................................................................................
(2)
A-Level
BIOLOGY
3.2 | b Immunity
Cell Recognition and Immune system
Time allowed
50 minutes
QUESTION PAPER
Score Percentage
/40 %
4.1 | CELL BIOLOGY | QUESTION PAPER 1 1
, Malaria is a disease caused by parasites belonging to the genus Plasmodium. Two species
that cause malaria are Plasmodium falciparum and Plasmodium vivax.
A test strip that uses monoclonal antibodies can be used to determine whether a person is
infected by Plasmodium. It can also be used to find which species of Plasmodium they are
infected by.
• A sample of a person’s blood is mixed with a solution containing an antibody, A, that
binds to a protein found in both species of Plasmodium. This antibody has a
coloured dye attached.
• A test strip is then put into the mixture. The mixture moves up the test strip by
capillary action to an absorbent pad.
• Three other antibodies, B, C and D are attached to the test strip. The position of
these antibodies and what they bind to is shown in Figure 1.
Figure 1
(a) Explain why antibody A attaches only to the protein found in species of
Plasmodium.
........................................................................................................................
........................................................................................................................
........................................................................................................................
........................................................................................................................
(2)
