Chapter 12: Anti-inflammatory, Antiarthritis, and Antigout Drugs

1. Apatientwithjointinflammationisprescribedananti-inflammatorydrug.Thepatientasksyouhowthisdrugworkstoaddressthisproblem.Whatisyourbe stresponse? a. “Anti-inflammatorydrugsreducepainandlimitbloodvesselresponsestojointinjury.” b. “Anti-inflammatorydrugscontainantibacterialandanti-inflammatoryproperties.” c. “Anti-inflammatorydrugslimitthebody’sresponsetocortisolinthebody.” d. “Anti-inflammatorydrugsincreasethereleaseofTNFandothermediators.” ANS: A Anti- inflammatorydrug’sprimarypurposeistoreducepainandpreventorlimitthetissueandbloodvessel responsestoinjuryorinvasion. DIF: CognitiveLevel:Applying REF: p.227 2. Apatientwithahistoryofcardiovasculardiseasehasbeenprescribedaspirindaily.Whatspecificrisk shouldthispatientbeinformedofbecauseoftakingaspirin? a. Riskofinfection b. Riskofbleeding c. Riskofliverimpairment d. Riskofcognitiveimpairment ANS: B Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe lifespanoftheplateletsoaslongas7to8days. DIF: CognitiveLevel:Applying REF: p.228 3. Amalepatienttakingdailyaspirinforthepreventionofcardiovascularcomplicationsinformsyouth atheisplanningtohaveatoothextractionnextweek.Whatcorrectinformationshouldbeprovidedtot hispatient? a. “Notifyyourhealthcareproviderandstoptakingtheaspirinbeforethedentalprocedure.” b. “Youmayrequireaspirinplusadditionalpaindrugafterthedentalprocedure.” c. “Takingenteric-coatedaspirinensuresyouwillnotbeatriskforanycomplications.” d. “Aspirinisassociatedwithtoothlossfollowingdentalsurgery.” ANS: A Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe lifespanoftheplateletaslongas7to8days.Thisisveryimportantifapatientisscheduledforaninvasiv eprocedureorsurgerysomakesuretonotifytheprescriberifthepatienthasanupcomingsurgery.