Exam (elaborations)

NEUR 205

Rating

Sold

Pages

Grade

A+

Uploaded on

18-04-2022

Written in

2021/2022

1. Whichneurotransmitterhasaninhibitoryactionwithinthecentralnervoussystem? a. Epinephrine b. Acetylcholine c. Norepinephrine d. Gamma-aminobutyricacid ANS: D Neurotransmitterscanbeexcitatoryorinhibitory.Excitatoryneurotransmittersincludeacetylcholi ne(Ach),epinephrine,andnorepinephrine.Inhibitoryneurotransmittersincludedopamine,somet ypesofserotonin,andGABA(gamma-aminobutyricacid). DIF: CognitiveLevel:Knowing REF: p.159 2. HowdoesthedrugtolcaponerelievethesymptomsofParkinsondisease? a Actsasadopamineagonist,replacingtheactivityofdopamine . b Forcesthesubstantianigratoincreasetheproductionandreleaseofnaturaldopamine . c Suppressestheactivityofanenzymethatnormallybreaksdownnaturallyoccurringdopamine . d Increasesthenumberofdopaminereceptorssitesthroughoutthecentralnervoussystem,thusinc . reasingtheeffectivenessofdopamineanddopamineagonists ANS: C Catechol-O-methyltransferase(COMT)isanenzymethatbreaksdown(metabolizes)naturallyoccurringcatech olamine-basedneurotransmitters,includingdopamine.Italsobreaksdowndopamineagonistdrugs.Catech ol-O-methyltransferase(COMT)inhibitorsaredrugsthatsuppresstheactivityoftheCOMTenzymesobo thnaturallyoccurringdopamineanddopamineagonistdrugsremainactiveinthebodylonger,helpin gtorestoretheacetylcholine– dopaminebalanceinthebrain.Entacapone(Comtan)andtolcapone(Tasmar)aretwoCOMTinhibit orsthatareusedcurrentlyforPD. DIF: CognitiveLevel:Understanding REF: p.162 3. Whyarecarbidopaandlevodopausuallygiventogether? a. Carbidopaisadopamineagonistandlevodopaisadopamineantagonist. b. Levodopaisadopamineagonistandcarbidopaisadopamineantagonist. c. Carbidopaenhancestheactionoflevodopa,andlessdrugisneeded. d. Levodopareversesorpreventsthesideeffectsofcarbidopa. ANS: C

Show more Read less

Institution

Course

Content preview

Chapter09:DrugTherapyforCentralN
ervousSystemProblems
[Document subtitle]

, Chapter09:DrugTherapyforCentralNervousSystemProblems
Visovsky:IntroductiontoClinicalPharmacology,9thEdition

MULTIPLECHOICE

1. Whichneurotransmitterhasaninhibitoryactionwithinthecentralnervoussystem?
a. Epinephrine
b. Acetylcholine
c. Norepinephrine
d. Gamma-aminobutyricacid
ANS: D
Neurotransmitterscanbeexcitatoryorinhibitory.Excitatoryneurotransmittersincludeacetylcholi
ne(Ach),epinephrine,andnorepinephrine.Inhibitoryneurotransmittersincludedopamine,somet
ypesofserotonin,andGABA(gamma-aminobutyricacid).

DIF: CognitiveLevel:Knowing REF: p.159

2. HowdoesthedrugtolcaponerelievethesymptomsofParkinsondisease?
a Actsasadopamineagonist,replacingtheactivityofdopamine
.
b Forcesthesubstantianigratoincreasetheproductionandreleaseofnaturaldopamine
.
c Suppressestheactivityofanenzymethatnormallybreaksdownnaturallyoccurringdopamine
.
d Increasesthenumberofdopaminereceptorssitesthroughoutthecentralnervoussystem,thusinc
. reasingtheeffectivenessofdopamineanddopamineagonists
ANS: C Catechol-O-
methyltransferase(COMT)isanenzymethatbreaksdown(metabolizes)naturallyoccurringcatech
olamine-
basedneurotransmitters,includingdopamine.Italsobreaksdowndopamineagonistdrugs.Catech ol-
O-methyltransferase(COMT)inhibitorsaredrugsthatsuppresstheactivityoftheCOMTenzymesobo
thnaturallyoccurringdopamineanddopamineagonistdrugsremainactiveinthebodylonger,helpin
gtorestoretheacetylcholine–
dopaminebalanceinthebrain.Entacapone(Comtan)andtolcapone(Tasmar)aretwoCOMTinhibit
orsthatareusedcurrentlyforPD.

DIF: CognitiveLevel:Understanding REF: p.162

3. Whyarecarbidopaandlevodopausuallygiventogether?
a. Carbidopaisadopamineagonistandlevodopaisadopamineantagonist.
b. Levodopaisadopamineagonistandcarbidopaisadopamineantagonist.
c. Carbidopaenhancestheactionoflevodopa,andlessdrugisneeded.
d. Levodopareversesorpreventsthesideeffectsofcarbidopa.
ANS: C

This study source was downloaded by 100000817936687 from CourseHero.com on 04 -13-2022 07:32:44 GMT -05:00

https://www.coursehero.com/file/72568880/Chapter9Pharmacologydocx/

Report Copyright Violation

Written for

Institution: Vanderbilt University
: Neuroscience

All documents for this subject (22)

Document information

Uploaded on: April 18, 2022
Number of pages: 8
Written in: 2021/2022
Type: Exam (elaborations)
Contains: Questions & answers

Subjects

chapter09drugtherapyforcentralnervoussystemproblems visovskyintroductiontoclinicalpharmacology
9thedition multiplechoice 1 whichneurotransmitterhasaninhibitoryactionwithinthecentralnervoussystem

$10.50

Get access to the full document:

Written by students who passed

Immediately available after payment

Read online or as PDF

Get to know the seller

ERICKWHITE

1.0

(1)

Get to know the seller

ERICKWHITE Chamberlain College Of Nursing

View profile

Sold

Member since

4 year

Number of followers

Documents

145

Last sold

2 year ago

1.0

1 reviews

Why students choose Stuvia

Created by fellow students, verified by reviews

Quality you can trust: written by students who passed their tests and reviewed by others who've used these notes.

Didn't get what you expected? Choose another document

No worries! You can instantly pick a different document that better fits what you're looking for.

Pay as you like, start learning right away

No subscription, no commitments. Pay the way you're used to via credit card and download your PDF document instantly.

“Bought, downloaded, and aced it. It really can be that simple.”

Alisha Student

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller ERICKWHITE. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $10.50. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews) 47251 documents were sold in the last 30 days Founded in 2010, the go-to place to buy study notes for 16 years now

NEUR 205

Content preview

Written for

Document information

Subjects

Get to know the seller

Recently viewed by you

Why students choose Stuvia

Created by fellow students, verified by reviews

Didn't get what you expected? Choose another document

Pay as you like, start learning right away

Working on your references?

Frequently asked questions

What do I get when I buy this document?

Satisfaction guarantee: how does it work?

Who am I buying these notes from?

Will I be stuck with a subscription?

Can Stuvia be trusted?