Chapter10:DrugTherapyforMentalHealth

Chapter10:DrugTherapyforMentalHealth
Visovsky:IntroductiontoClinicalPharmacology,9thEdition


MULTIPLECHOICE

1. Whichdrugcategoryisusefulinpromotingsleepamongpatientswithinsomnia?
a. Sedatives
b. ACEinhibitors
c. Atypicalantipsychotics
d. Selectiveserotoninreuptakeinhibitors
ANS: A
Sedativesaredrugsthathavethemainpurposeofpromotingsleepbychangingsignalsinthecentraln
ervoussystemandreducingresponsestostimulation.

DIF: CognitiveLevel:Knowing REF: p.184

2.

YouarepreparingtogivethebenzodiazepineValiumtoapatientasapremedicationbeforesurgery.T
hepatientasksyouhowthisdrugworks.Whatisyourbestresponse?
a. “ThisdrugworksbybindingtoreceptorsactingwithGABAtoinducesleep.”
b. “Thisdrugisactsbypreventingbindingtothebenzodiazepinereceptors.”
c. “ThisdrugactsbyinhibitingGABAresponsestorelaxmuscles.”
d. “Thisdrugactsbybindingtoopioidreceptors.”
ANS: A
BenzodiazepinesaresedatinghypnoticdrugsthatdepresstheCNSbybindingtobenzodiazepine(B
NZ)receptorsthatactwithgamma-
aminobutyricacid(GABA)receptorstoenhanceGABAeffects,resultingsleepandmusclerelaxati
on.

DIF: CognitiveLevel:Applying REF: p.186

3.

Youarecaringforapatientintheclinicsettingwhohasbeentakingabenzodiazepinealprazolam(Xan
ax)foranxiety.Whatpotentialproblemshouldyouobservethispatientfor?
a. Seizureactivity
b. Addiction
c. Insomnia
d. Anorexia
ANS: B
Thebenzodiazepineshaveahigherriskforaddictionanddependencythandothenonbenzodiazepin
es.Theyalsocarryablackboxwarningforcentralnervoussystemdepression.Overdosesarepossibl
eandserious.

DIF: CognitiveLevel:Understanding REF: p.185



This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:41:04 GMT -05:00


https://www.coursehero.com/file/72568444/Chapter10Pharmacologydocx/

, 4.

Whichdrugwouldyouanticipatewillbegiventoapatientwhoexperiencedanoverdoseofabenzodia
zepine?
a. Rifampin
b. Naloxone
c. Flumazenil
d. Epinepherine
ANS: C
Thedrugflumazenil(Romazicon)isabenzodiazepinereceptorantagonistandisanantidoteusedtor
everseanoverdoseofeitherabenzodiazepinesedativeoranonbenzodiazepinesedative.Foradults,i
tisgivenintravenouslywithaninitialdoseof0.2mg.Ifthereisnoresponseafter45seconds,thedosec
anberepeated.Afterthat,itcanberepeatedeveryminuteforatotalof4doses.

DIF: CognitiveLevel:Knowing REF: p.187

5. Forwhichpatientwouldbenzodiazepinesbecontraindicated?
a. Afemalewithbreastcancer.
b. Awomanwhois20weekspregnant.
c. Amalewhohasahistoryofsmoking.
d. Amalewhoisabouttoundergosurgery.
ANS: B
Pregnancyisanabsolutecontraindicationforthebenzodiazepinesbecausetheyhaveahighriskforc
ausingbirthdefects.Althoughthechemicalstructureofthenonbenzodiazepines(benzodiazepinea
gonists)isdifferent,thesedrugsbindtothesamereceptorsandhavesimilaractions.Asaresult,theyar
enotrecommendedduringpregnancy.

DIF: CognitiveLevel:Applying REF: p.185

6.

Whatspecificinformationshouldbepartoftheteachingplanforapatienttakinganonbenzodiazepin
esedative?
a. Thesedrugscaninteractwithmanyfoodsandbeverages.
b. Thesedrugscancauseyoutobephysicallyactiveatnight.
c. Thesedrugsmustbetakesforatleast6weekstoseeanyeffects.
d. Excesscaffeineintakecanworktoincreasetheeffectivenessofthesedrugs.
ANS: B
Whentakinganonbenzodiazepine(benzodiazepineagonist),beawarethatdrugsfromthisclasscan
causeyoutobephysicallyactiveatnight,evengoingforadrive,withoutyourknowledgeormemoryo
ftheevent.Itisbesttohaveafamilymemberorfriendwatchoutfortheseeffectswhenyoufirststarttaki
ngthedrug.

DIF: CognitiveLevel:Applying REF: p.186




This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:41:04 GMT -05:00


https://www.coursehero.com/file/72568444/Chapter10Pharmacologydocx/