Chapter 12: Anti-inflammatory, Antiarthritis, and Antigout Drugs
Visovsky: Introduction to Clinical Pharmacology, 9 th Edition
MULTIPLE CHOICE
1. Apatientwithjointinflammationisprescribedananti-
inflammatorydrug.Thepatientasksyouhowthisdrugworkstoaddressthisproblem.Whatisyourbe
stresponse?
a. “Anti-inflammatorydrugsreducepainandlimitbloodvesselresponsestojointinjury.”
b. “Anti-inflammatorydrugscontainantibacterialandanti-inflammatoryproperties.”
c. “Anti-inflammatorydrugslimitthebody’sresponsetocortisolinthebody.”
d. “Anti-inflammatorydrugsincreasethereleaseofTNFandothermediators.”
ANS: A
Anti-
inflammatorydrug’sprimarypurposeistoreducepainandpreventorlimitthetissueandbloodvessel
responsestoinjuryorinvasion.
DIF: CognitiveLevel:Applying REF: p.227
2.
Apatientwithahistoryofcardiovasculardiseasehasbeenprescribedaspirindaily.Whatspecificrisk
shouldthispatientbeinformedofbecauseoftakingaspirin?
a. Riskofinfection
b. Riskofbleeding
c. Riskofliverimpairment
d. Riskofcognitiveimpairment
ANS: B
Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe
lifespanoftheplateletsoaslongas7to8days.
DIF: CognitiveLevel:Applying REF: p.228
3.
Amalepatienttakingdailyaspirinforthepreventionofcardiovascularcomplicationsinformsyouth
atheisplanningtohaveatoothextractionnextweek.Whatcorrectinformationshouldbeprovidedtot
hispatient?
a. “Notifyyourhealthcareproviderandstoptakingtheaspirinbeforethedentalprocedure.”
b. “Youmayrequireaspirinplusadditionalpaindrugafterthedentalprocedure.”
c. “Takingenteric-coatedaspirinensuresyouwillnotbeatriskforanycomplications.”
d. “Aspirinisassociatedwithtoothlossfollowingdentalsurgery.”
ANS: A
Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe
lifespanoftheplateletaslongas7to8days.Thisisveryimportantifapatientisscheduledforaninvasiv
eprocedureorsurgerysomakesuretonotifytheprescriberifthepatienthasanupcomingsurgery.
This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:50:34 GMT -05:00
https://www.coursehero.com/file/72568549/Chapter12Pharmacologydocx/
, DIF: CognitiveLevel:Applying REF: p.228
4.
YouarepreparingateachingplanforapatientprescribedthenonselectiveNSAIDibuprofen800mg
orallydaily.Whichofthefollowinginstructionsshouldbeincludedinthisteachingplan?
a. Avoideatingexcessiveamountsofproteinasthiscaninterferewiththedrug’saction.
b. Thisdrugcanincreaseserumbloodsugarlevelsinpatientswithdiabetes.
c. Takingthisdrugbeforebedcancauseexcessivenight-timeurination.
d. TakethisdrugwithfoodtopreventGIupset.
ANS: D
IfNSAIDScausemildGIupset,thepatientmaytakethedrugwithasmallamountoffoodormilk.Thes
edrugsdecreasebloodsugar,makingdiabeticsathighriskforhypoglycemia.NSAIDscancauseflui
dretention.
DIF: CognitiveLevel:Applying REF: p.228
5.
Apatientreportsringinginherearswhiletakingaspirinfourtimesadaytorelievearthritispain.Whata
ctionshouldyoutake?
a. Instructthepatienttoreducethedoseofaspirinbyhalfuntiltheringingstops.
b. Noactionisneeded;thisisanexpectedresponsetothisdoseofaspirin.
c. Callthehealthcareprovider,asthisisadversereactiontothedrug.
d. Instructthepatienttotakethefulldosebeforebed.
ANS: C
Tinnitus(ringingintheears)isanadversereactiontoanti-inflammatoryanalgesics.
DIF: CognitiveLevel:Applying REF: p.230
6.
Amotherbringsherfebrileinfanttothepediatricclinicforevaluation.Theinfanthasatemperatureof
102degrees.Themothertellsyouthatshewishesshehadgiventhebabyadoseofliquidaspirinbeforel
eavingthehousetobringdownthebaby’stemperature.Whatisyourbestresponse?
a. “Aspirincanbedangerous,andshouldnotbegiventoinfants.”
b. “Wecangivethebabyadosenowbeforeyouleavetheclinic.”
c. “Giveaspirinalternatingwithacetaminophenevery4hforfever.”
d. “Aspirinwillneedtobegivenwithaproton-pumpinhibitortopreventbleeding.”
ANS: A
Aspirinshouldnotbegiventoinfantsorchildrenwhohaveanacuteillnessbecauseofitsassociationw
ithdevelopmentofaveryseriousproblemknownasReyesyndrome.Thisdisordercanleadtomental
deficits,coma,ordeath.
DIF: CognitiveLevel:Applying REF: p.229
This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:50:34 GMT -05:00
https://www.coursehero.com/file/72568549/Chapter12Pharmacologydocx/
Visovsky: Introduction to Clinical Pharmacology, 9 th Edition
MULTIPLE CHOICE
1. Apatientwithjointinflammationisprescribedananti-
inflammatorydrug.Thepatientasksyouhowthisdrugworkstoaddressthisproblem.Whatisyourbe
stresponse?
a. “Anti-inflammatorydrugsreducepainandlimitbloodvesselresponsestojointinjury.”
b. “Anti-inflammatorydrugscontainantibacterialandanti-inflammatoryproperties.”
c. “Anti-inflammatorydrugslimitthebody’sresponsetocortisolinthebody.”
d. “Anti-inflammatorydrugsincreasethereleaseofTNFandothermediators.”
ANS: A
Anti-
inflammatorydrug’sprimarypurposeistoreducepainandpreventorlimitthetissueandbloodvessel
responsestoinjuryorinvasion.
DIF: CognitiveLevel:Applying REF: p.227
2.
Apatientwithahistoryofcardiovasculardiseasehasbeenprescribedaspirindaily.Whatspecificrisk
shouldthispatientbeinformedofbecauseoftakingaspirin?
a. Riskofinfection
b. Riskofbleeding
c. Riskofliverimpairment
d. Riskofcognitiveimpairment
ANS: B
Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe
lifespanoftheplateletsoaslongas7to8days.
DIF: CognitiveLevel:Applying REF: p.228
3.
Amalepatienttakingdailyaspirinforthepreventionofcardiovascularcomplicationsinformsyouth
atheisplanningtohaveatoothextractionnextweek.Whatcorrectinformationshouldbeprovidedtot
hispatient?
a. “Notifyyourhealthcareproviderandstoptakingtheaspirinbeforethedentalprocedure.”
b. “Youmayrequireaspirinplusadditionalpaindrugafterthedentalprocedure.”
c. “Takingenteric-coatedaspirinensuresyouwillnotbeatriskforanycomplications.”
d. “Aspirinisassociatedwithtoothlossfollowingdentalsurgery.”
ANS: A
Patientswhotakeaspirinmustbemonitoredforbleedingduetoirreversibleplateletinhibitionforthe
lifespanoftheplateletaslongas7to8days.Thisisveryimportantifapatientisscheduledforaninvasiv
eprocedureorsurgerysomakesuretonotifytheprescriberifthepatienthasanupcomingsurgery.
This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:50:34 GMT -05:00
https://www.coursehero.com/file/72568549/Chapter12Pharmacologydocx/
, DIF: CognitiveLevel:Applying REF: p.228
4.
YouarepreparingateachingplanforapatientprescribedthenonselectiveNSAIDibuprofen800mg
orallydaily.Whichofthefollowinginstructionsshouldbeincludedinthisteachingplan?
a. Avoideatingexcessiveamountsofproteinasthiscaninterferewiththedrug’saction.
b. Thisdrugcanincreaseserumbloodsugarlevelsinpatientswithdiabetes.
c. Takingthisdrugbeforebedcancauseexcessivenight-timeurination.
d. TakethisdrugwithfoodtopreventGIupset.
ANS: D
IfNSAIDScausemildGIupset,thepatientmaytakethedrugwithasmallamountoffoodormilk.Thes
edrugsdecreasebloodsugar,makingdiabeticsathighriskforhypoglycemia.NSAIDscancauseflui
dretention.
DIF: CognitiveLevel:Applying REF: p.228
5.
Apatientreportsringinginherearswhiletakingaspirinfourtimesadaytorelievearthritispain.Whata
ctionshouldyoutake?
a. Instructthepatienttoreducethedoseofaspirinbyhalfuntiltheringingstops.
b. Noactionisneeded;thisisanexpectedresponsetothisdoseofaspirin.
c. Callthehealthcareprovider,asthisisadversereactiontothedrug.
d. Instructthepatienttotakethefulldosebeforebed.
ANS: C
Tinnitus(ringingintheears)isanadversereactiontoanti-inflammatoryanalgesics.
DIF: CognitiveLevel:Applying REF: p.230
6.
Amotherbringsherfebrileinfanttothepediatricclinicforevaluation.Theinfanthasatemperatureof
102degrees.Themothertellsyouthatshewishesshehadgiventhebabyadoseofliquidaspirinbeforel
eavingthehousetobringdownthebaby’stemperature.Whatisyourbestresponse?
a. “Aspirincanbedangerous,andshouldnotbegiventoinfants.”
b. “Wecangivethebabyadosenowbeforeyouleavetheclinic.”
c. “Giveaspirinalternatingwithacetaminophenevery4hforfever.”
d. “Aspirinwillneedtobegivenwithaproton-pumpinhibitortopreventbleeding.”
ANS: A
Aspirinshouldnotbegiventoinfantsorchildrenwhohaveanacuteillnessbecauseofitsassociationw
ithdevelopmentofaveryseriousproblemknownasReyesyndrome.Thisdisordercanleadtomental
deficits,coma,ordeath.
DIF: CognitiveLevel:Applying REF: p.229
This study source was downloaded by 100000817936687 from CourseHero.com on 04-13-2022 07:50:34 GMT -05:00
https://www.coursehero.com/file/72568549/Chapter12Pharmacologydocx/
