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Older client with a decreased percentage of lean body receives a Rx that is
adjusted based on which pharmacokinetic process?
Distribution
A decreased lean body mass in an older adult affects the distribution of drugs
(D), which affects the pharmacokinetics of drugs. Decreased gastric pH, delayed
gastric emptying, decreased splanchnic blood flow, decreased gastrointestinal
absorption surface areas and motility affect (A) in the older adult population.
Decreased hepatic blood flow, decreased hepatic mass, and decreased activity
of hepatic enzymes affect (B) in older adults. Decreased renal blood flow,
decreased glomerular filtration rate, decreased tubular secretion, and decreased
number of nephrons affects (C) in an older adult.
Know the insulins and their peak/onset (there are several Qs about this in
different formats)
Rapid-Lispro (Humalog) and Aspart (Novolog) Onset: 5-15 minutes
Peak: . 5-1.5 hours
Short acting- regular (humulin) Onset: 30-60 minutes Peak: 2-3 hours (IV
ok)
Intermediate acting- NPH Onset: 1-2 hours Peak 6-12 hours
Long acting- Glargine (lantus) Onset: 1.1 hour Peak: 14-20 hours (DO NOT
MIX)
Chlamidia
Tetracycline
Trichomoniasis
Flagyl
Candidiasis
Nystatin
Pharmacology Exit HESI exam questions
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,Pharmacology Exit HESI exam questions
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Herpes Simplex 2
Acyclovir
Parkinson’s disease
Levodopa/Carbidopa
Phenobarbitol
Seizures
Nurse is conducting DC teaching about anti-anxiety drug diazepam (valium)
Evaluate the ingredients of all over-the-counter drugs for alcohol content
Nursing instruction most important for patient on Zyloprim
Increase fluid intake
Client getting Tofranil (Imipramine)
Give medication at night
Magnesium antidote
Calcium gluconate
Patient with hyperthyroidism taking inderal (propanalol)
Decreases pulse rate
A client with hyperthyroidism is receiving propranolol (Inderal). Which finding indicates
that the medication is having the desired effect?
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,Pharmacology Exit HESI exam questions
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• Decrease in serum T4 levels
• Increase in blood pressure
• Decrease in pulse rate
• Goiter no longer palpable
Medication dosing-heparin 25000 units at 7ml/hr doctor changed rate to
900 units what is the
Mls/hr
Med was ordered 100mg in 4 divided doses in 24 hours available in
25mg, how many will you give every 6 hours
1
Patient on benzos
Answer is not narcan
- A client experiencing withdrawal from the benzodiazepines alprazolam (Xanax) is
demonstrating severe agitation and tremors. What is the best initial nursing
action?
• Administer naloxone (Narcan) per PNR protocol
• Initiate seizure precautions
• Obtain a serum drug screen
• Instruct the family about withdrawal symptoms.
• Rationale: Withdrawal of CNS depressants, such as Xanax, results in rebound
over-excitation of the CNS. Since the client exhibiting tremors, the nurse
should anticipate seizure activity and protect the client.
Patient Dx with bipolar-how to know if meds are effective
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Family states patient is doing better with manic phases
- A client with bipolar disorder began taking valproic acid (Depakote) 250
mg PO three times daily two months ago. Which finding provides the best
indication that the medication regimen is effective?
•The family reports a great reduction in client’s maniac behavior
Pharmacology Exit HESI exam questions
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