NEW PRACTICE EXAM SOLUTION 2022 FOR PHARM II
(REPRODUCTIVE DISORDERS)
1. What are the causes of erectile dysfunction? - CORRECT ANSWER 1.
Associated w/ vascular diseases or meds (thiazide diuretics, B-blockers, SSRIs,
TCAs, diazepam
2. psychogenic causes: depression, fatigue, anxiety
3. organic causes: damage to involved nerves or blood vessels
4. recreational drugs: ETOH, barbiturates, smoking
2. What is SILDENAFIL? - CORRECT ANSWER 1. phosphodiesterase-5 inhibitor--
> cellular messenger that results in vasodilation
2. relaxes smooth muscle in corpus cavernosum
3. allows increased blood flow to penis
4. PRIMARY USE: ED
-take b4 sexual activity
3. What is TADALAFIL? - CORRECT ANSWER 1. phosphodiesterase-5 inhibitor
2. increases signaling via protein kinase G cascade to decrease Ca entry into smooth
muscle cells--> relaxation allowing blood to fill corpus cavernosum
3. PRIMARY USE: ED
-take b4 sexual activity
4. What is the action of SILDENAFIL (viagra)? - CORRECT ANSWER 1. relaxes
smooth muscle
5. What is the onset of SILDENAFIL? - CORRECT ANSWER 1. 20-60 min
lasts 1-2 hrs
6. What are the adverse effects of SILDENAFIL? - CORRECT ANSWER 1.
HYPOTENSION
,2. PRIAPISM
3. headache
4. dizziness
5. flushing, rash
6. nasal congestion
7. diarrhea
8. dyspepsia
7. What are the teaching points for SILDENAFIL and TADALAFIL? - CORRECT
ANSWER 1. monitor for dizziness when standing up from sitting
2. CAN'T TAKE OTHER VASODILATORS (NITROGLYCERINE)
3. CONTRAINDICATED W/LIVER DISEASE
8. What is the action of TADALAFIL (cialis)? - CORRECT ANSWER 1. relaxes
smooth muscle
9. What is the onset of TADALAFIL? - CORRECT ANSWER 1. onset: 20-30 min
Lasts 24-36 hrs
10. What are the adverse effects of TADALAFIL? - CORRECT ANSWER 1.
HYPOTENSION
2. headache
3. blurred vision
4. flushing
11. What are the nursing considerations for PDE5 Inhibitors? - CORRECT ANSWER
1. obtain physical exam and hx
-sexual dysfunction
-CVD, BP
2. monitor liver function labs
, 3. confirming diagnostics
-testosterone, prolactin, thyroxin levels
-blood flow test to determine level of flow to penis
4. OCNTRAINDICARED W/USE OF ORGANIC NITRATES AND ALPHA-
ADRENERGIC BLOCKERS
-WORSEN HYPOTENSION
12. What is benign prostatic hyperplasia? - CORRECT ANSWER 1. BENIGN cellular
overgrowth of prostate; may cause uretheral blockage
2. most common neoplasm in men
3 BPH is NOT cancer
13. What are the risk factor for BPH? - CORRECT ANSWER 1. aging
2. fam hx
3. diabetes
4. heart disease
5. obesity
14. What are the symptoms of BPH? - CORRECT ANSWER 1. FREQUENCY
2. urgency
3. post-void leakage
4. nocturia
5. DECREASED FORCE OF STREAM
6. sensation of not emptying bladder
15. What are the medications for BPH? - CORRECT ANSWER 1. Alpha adrenergic
blockers (osin's): TAMSULOSIN (FLOMAX)
-relax smooth muscle
-improve urine flow in 1-2 weeks
(REPRODUCTIVE DISORDERS)
1. What are the causes of erectile dysfunction? - CORRECT ANSWER 1.
Associated w/ vascular diseases or meds (thiazide diuretics, B-blockers, SSRIs,
TCAs, diazepam
2. psychogenic causes: depression, fatigue, anxiety
3. organic causes: damage to involved nerves or blood vessels
4. recreational drugs: ETOH, barbiturates, smoking
2. What is SILDENAFIL? - CORRECT ANSWER 1. phosphodiesterase-5 inhibitor--
> cellular messenger that results in vasodilation
2. relaxes smooth muscle in corpus cavernosum
3. allows increased blood flow to penis
4. PRIMARY USE: ED
-take b4 sexual activity
3. What is TADALAFIL? - CORRECT ANSWER 1. phosphodiesterase-5 inhibitor
2. increases signaling via protein kinase G cascade to decrease Ca entry into smooth
muscle cells--> relaxation allowing blood to fill corpus cavernosum
3. PRIMARY USE: ED
-take b4 sexual activity
4. What is the action of SILDENAFIL (viagra)? - CORRECT ANSWER 1. relaxes
smooth muscle
5. What is the onset of SILDENAFIL? - CORRECT ANSWER 1. 20-60 min
lasts 1-2 hrs
6. What are the adverse effects of SILDENAFIL? - CORRECT ANSWER 1.
HYPOTENSION
,2. PRIAPISM
3. headache
4. dizziness
5. flushing, rash
6. nasal congestion
7. diarrhea
8. dyspepsia
7. What are the teaching points for SILDENAFIL and TADALAFIL? - CORRECT
ANSWER 1. monitor for dizziness when standing up from sitting
2. CAN'T TAKE OTHER VASODILATORS (NITROGLYCERINE)
3. CONTRAINDICATED W/LIVER DISEASE
8. What is the action of TADALAFIL (cialis)? - CORRECT ANSWER 1. relaxes
smooth muscle
9. What is the onset of TADALAFIL? - CORRECT ANSWER 1. onset: 20-30 min
Lasts 24-36 hrs
10. What are the adverse effects of TADALAFIL? - CORRECT ANSWER 1.
HYPOTENSION
2. headache
3. blurred vision
4. flushing
11. What are the nursing considerations for PDE5 Inhibitors? - CORRECT ANSWER
1. obtain physical exam and hx
-sexual dysfunction
-CVD, BP
2. monitor liver function labs
, 3. confirming diagnostics
-testosterone, prolactin, thyroxin levels
-blood flow test to determine level of flow to penis
4. OCNTRAINDICARED W/USE OF ORGANIC NITRATES AND ALPHA-
ADRENERGIC BLOCKERS
-WORSEN HYPOTENSION
12. What is benign prostatic hyperplasia? - CORRECT ANSWER 1. BENIGN cellular
overgrowth of prostate; may cause uretheral blockage
2. most common neoplasm in men
3 BPH is NOT cancer
13. What are the risk factor for BPH? - CORRECT ANSWER 1. aging
2. fam hx
3. diabetes
4. heart disease
5. obesity
14. What are the symptoms of BPH? - CORRECT ANSWER 1. FREQUENCY
2. urgency
3. post-void leakage
4. nocturia
5. DECREASED FORCE OF STREAM
6. sensation of not emptying bladder
15. What are the medications for BPH? - CORRECT ANSWER 1. Alpha adrenergic
blockers (osin's): TAMSULOSIN (FLOMAX)
-relax smooth muscle
-improve urine flow in 1-2 weeks
