2022 NEW EXAM REVIEW FOR PHARMACOLOGY II (BLOOD PRODUCTS | TRANSFUSION)
COMPLETE SOLUTION
What are PRBCs? - -shelf life is 42 days after donation, can be frozen (though rare) for 10 years
-need to know ABO and RH compatibility
-from a human donor, is real tissue
What is the purpose of PRBCs? - -replenish RBC so order to correct anemia or hemorrhage
-GOAL: INCREASE O2 TRANSPORTATION (hgb too low = cannot transport O2)
--correct anemia
--hgb<7-8 and >30% blood loss
What is the PRBC dosage? - 1 bag = 1 unit
will raise hgb by 1 gm/dl, hct by 3%
A+ can receive blood from - A+, A-, O+, O-
A- can receive blood from - A-, O-
B+ can receive blood from - B+, B-, O+, O-
B- can receive blood from - B-, O-
AB+ can receive blood from - All blood types
AB- can receive blood from - O-, AB-, A-, B-
O+ can receive blood from - O+, O-
O- can receive blood from - O-
, What complications occur with Rh- and pregnancy? - Mother is Rh negative and fetus is Rh positive.
Fetal blood and maternal blood mix. Next birth, if Rh positive, then antibodies will cause fetal blood to
agglutinate. (SECOND PREGNANCY)
What are the infectious complications of PRBC? - -VERY rare now because all blood donations are
screened for HIV and if found positive the blood is destroyed
-important to educate patients on this if worried
What are the PRBC transfusion complications? - 1.) ACUTE
-REACTION
---ACUTE HEMOLYTIC
---ALLERGIC
---FEBRILE NONHEMOLYTIC
-LUNG INJURY
-hypervolemia
-urticaria
-septicemia
2.) DELAYED HEMOLYTIC REACTION
What does a delayed hemolytic transfusion reaction cause? - - d/t ABO incompatibility
-immune destruction of transfused RBC (mislabeling T/C, fail to match with right blood type)
-develops QUICKLY
What are the s/sx of hemolytic transfusion reactions? - 1.)ANXIETY
2.) DYSPNEA
3.) FEVER
4.) chills
5.) pain
6.) dark urine
COMPLETE SOLUTION
What are PRBCs? - -shelf life is 42 days after donation, can be frozen (though rare) for 10 years
-need to know ABO and RH compatibility
-from a human donor, is real tissue
What is the purpose of PRBCs? - -replenish RBC so order to correct anemia or hemorrhage
-GOAL: INCREASE O2 TRANSPORTATION (hgb too low = cannot transport O2)
--correct anemia
--hgb<7-8 and >30% blood loss
What is the PRBC dosage? - 1 bag = 1 unit
will raise hgb by 1 gm/dl, hct by 3%
A+ can receive blood from - A+, A-, O+, O-
A- can receive blood from - A-, O-
B+ can receive blood from - B+, B-, O+, O-
B- can receive blood from - B-, O-
AB+ can receive blood from - All blood types
AB- can receive blood from - O-, AB-, A-, B-
O+ can receive blood from - O+, O-
O- can receive blood from - O-
, What complications occur with Rh- and pregnancy? - Mother is Rh negative and fetus is Rh positive.
Fetal blood and maternal blood mix. Next birth, if Rh positive, then antibodies will cause fetal blood to
agglutinate. (SECOND PREGNANCY)
What are the infectious complications of PRBC? - -VERY rare now because all blood donations are
screened for HIV and if found positive the blood is destroyed
-important to educate patients on this if worried
What are the PRBC transfusion complications? - 1.) ACUTE
-REACTION
---ACUTE HEMOLYTIC
---ALLERGIC
---FEBRILE NONHEMOLYTIC
-LUNG INJURY
-hypervolemia
-urticaria
-septicemia
2.) DELAYED HEMOLYTIC REACTION
What does a delayed hemolytic transfusion reaction cause? - - d/t ABO incompatibility
-immune destruction of transfused RBC (mislabeling T/C, fail to match with right blood type)
-develops QUICKLY
What are the s/sx of hemolytic transfusion reactions? - 1.)ANXIETY
2.) DYSPNEA
3.) FEVER
4.) chills
5.) pain
6.) dark urine
