AGNP Board Exam – Hematology Prescription Exam
1. Question:
Folic acid (vitamin B9) is used to treat:
microcytic anemia.
anemia of chronic disease.
macrocytic anemia. Correct
normochromic anemia.
Explanation:
Folic acid (vitamin B9) is used to treat macrocytic anemia secondary to folic
acid deficiency. Folic acid is necessary for purine and pyrimidine synthesis,
and is required for nucleoprotein synthesis and maintenance in
erythropoiesis. It stimulates WBC and platelet production in folate deficiency
anemia.
2. Question:
When taking corticosteroids for the treatment of immune thrombocytopenia,
stopping them abruptly could result in:
hypertension.
hyperkalemia.
Cushing's syndrome.
an adrenal crisis. Correct
Explanation:
Corticosteroids should not be stopped suddenly after prolonged use. This can
result in adrenal crisis because of the body's inability to secrete enough
cortisol to make up for the withdrawal. Nausea, vomiting, and shock are the
reported side effects of adrenal crisis. Cushing's syndrome is just the
opposite. It results from excessive amounts of cortisol.
3. Question:
The most common side effect of ferrous sulfate is:
headache.
dizziness.
fatigue.
constipation. Correct
Explanation:
The most common side effect of ferrous sulfate is constipation. Headache,
dizziness and fatigue may be signs and symptoms of anemia.
4. Question:
, Another name for vitamin B12 is:
biotin.
cyanocobalamin. Correct
riboflavin.
thiamin.
Explanation:
Another name for vitamin B12 is cyanocobalamin. Biotin is vitamin B7;
riboflavin is vitamin B2; and thiamin is vitamin B1.
5. Question:
Folic acid (vitamin B9) is:
beneficial in the treatment of pernicious anemia.
administered only in conjunction with vitamin B12.
may correct neurologic manifestations of anemia.
a water-soluble vitamin. Correct
Explanation:
Folic acid (vitamin B9) is a water-soluble vitamin and is excreted when stores
are adequate. It can be administered orally, intramuscularly, intravenously,
or subcutaneously. Doses of folic acid above 0.1 mg daily may obscure
pernicious anemia. This condition is discovered when hematologic remission
occurs as neurologic manifestations remain progressive. Administration of
folic acid alone is improper therapy for pernicious anemia and other
megaloblastic anemias in which vitamin B12 is deficient.
6. Question:
After correcting a decreased hemoglobin in a patient who has iron deficiency
anemia, oral iron supplementation should be continued for at least:
2 weeks.
4 weeks.
8 weeks.
12 weeks. Correct
Explanation:
To replete iron stores, treat for 3 to 6 months after hemoglobin has
normalized. Initial treatment of iron deficiency anemia is usually with oral
iron (ferrous sulfate, ferrous gluconate, or ferrous fumarate). The reticulocyte
count should peak at 1 to 2 weeks, hemoglobin after 2 to 4 months, and
replacement of iron stores after 6 months.
7. Question:
Folic acid is also known as:
vitamin B1.
vitamin B6.
1. Question:
Folic acid (vitamin B9) is used to treat:
microcytic anemia.
anemia of chronic disease.
macrocytic anemia. Correct
normochromic anemia.
Explanation:
Folic acid (vitamin B9) is used to treat macrocytic anemia secondary to folic
acid deficiency. Folic acid is necessary for purine and pyrimidine synthesis,
and is required for nucleoprotein synthesis and maintenance in
erythropoiesis. It stimulates WBC and platelet production in folate deficiency
anemia.
2. Question:
When taking corticosteroids for the treatment of immune thrombocytopenia,
stopping them abruptly could result in:
hypertension.
hyperkalemia.
Cushing's syndrome.
an adrenal crisis. Correct
Explanation:
Corticosteroids should not be stopped suddenly after prolonged use. This can
result in adrenal crisis because of the body's inability to secrete enough
cortisol to make up for the withdrawal. Nausea, vomiting, and shock are the
reported side effects of adrenal crisis. Cushing's syndrome is just the
opposite. It results from excessive amounts of cortisol.
3. Question:
The most common side effect of ferrous sulfate is:
headache.
dizziness.
fatigue.
constipation. Correct
Explanation:
The most common side effect of ferrous sulfate is constipation. Headache,
dizziness and fatigue may be signs and symptoms of anemia.
4. Question:
, Another name for vitamin B12 is:
biotin.
cyanocobalamin. Correct
riboflavin.
thiamin.
Explanation:
Another name for vitamin B12 is cyanocobalamin. Biotin is vitamin B7;
riboflavin is vitamin B2; and thiamin is vitamin B1.
5. Question:
Folic acid (vitamin B9) is:
beneficial in the treatment of pernicious anemia.
administered only in conjunction with vitamin B12.
may correct neurologic manifestations of anemia.
a water-soluble vitamin. Correct
Explanation:
Folic acid (vitamin B9) is a water-soluble vitamin and is excreted when stores
are adequate. It can be administered orally, intramuscularly, intravenously,
or subcutaneously. Doses of folic acid above 0.1 mg daily may obscure
pernicious anemia. This condition is discovered when hematologic remission
occurs as neurologic manifestations remain progressive. Administration of
folic acid alone is improper therapy for pernicious anemia and other
megaloblastic anemias in which vitamin B12 is deficient.
6. Question:
After correcting a decreased hemoglobin in a patient who has iron deficiency
anemia, oral iron supplementation should be continued for at least:
2 weeks.
4 weeks.
8 weeks.
12 weeks. Correct
Explanation:
To replete iron stores, treat for 3 to 6 months after hemoglobin has
normalized. Initial treatment of iron deficiency anemia is usually with oral
iron (ferrous sulfate, ferrous gluconate, or ferrous fumarate). The reticulocyte
count should peak at 1 to 2 weeks, hemoglobin after 2 to 4 months, and
replacement of iron stores after 6 months.
7. Question:
Folic acid is also known as:
vitamin B1.
vitamin B6.
