AGNP Board Exam Eye, Ear, Nose, Throat
Prescription Exam
1. Question:
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis,
should be administered:
with milk.
with meals.
on an empty stomach. Correct
with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1
hour prior to, or 2 hours after meals) to increase total absorption and with
adequate amount of fluid to reduce the risk of esophageal irritation and
ulceration. It should be administered at least 1 to 2 hours prior to, or 4 hours
after, an antacid containing aluminum and magnesium cations. It may
chelate with tetracycline (Sumycin) and reduce its total absorption. Serum
concentrations may be decreased if taken with dairy products.
2. Question:
The brand name for sulfacetamide ophthalmic is:
AzaSite.
Bleph-10. Correct
Besivance.
Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the
brand name of azithromycin. Besifloxacin is the generic name for Besivance.
The generic name of Garamycin is gentamicin sulfate.
3. Question:
The generic name for Polytrim ophthalmic is:
trimethoprim and polymyxin B. Correct
bacitracin/polymyxin B.
azithromycin.
besifloxacin.
,Explanation:
The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is
the brand name for bacitracin/polymyxin B. The brand name for azithromycin
is AzaSite. Besifloxacin brand name is Besivance.
4. Question:
Which of the following does NOT cause a drug-disease interaction when
using a decongestant/antihistamine medication such as
Naphazoline/pheniramine (Naphcon-A)?
Cardiovascular disease
Angle-closure glaucoma
Prostatic hypertrophy
Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-
A) include angle-closure glaucoma, MAOI inhibitor use within 14 days,
cardiovascular disease, hypertension, diabetes mellitus, prostatic
hypertrophy and urinary tract obstruction.
5. Question:
The maximum daily dose of acetaminophen for ages 12 years and older is:
1200 milligrams/day.
2000 milligrams/day.
3000 milligrams/day.
4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause
liver damage. Doses of 4000 mg (4 grams) per day should not be exceeded
in patients 12 years and older. Maximum dose in neonates is 60 mg/kg/day
and 75 mg/kg/day in infants and children.
6. Question:
,For treatment of blepharitis, patients should be instructed to apply
erythromycin ointment to the affected eye using:
a 0.5 inch ribbon 3 times daily for 5 days.
a 0.5 cm ribbon 3 times daily for 5 days.
a 1-inch ribbon 5 times daily for 7 days.
a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin
ophthalmic ointment up to 6 times daily for up to 10 days.
7. Question:
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is
indicated in the treatment of:
acute conjunctivitis.
vernal conjunctivitis. Correct
fungal keratitis.
herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control
allergic conditions. It is indicated in the treatment of vernal
keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. Vernal
conjunctivitis is long-term inflammation of the outer lining of the eyes. It is
due to an allergic reaction.
8. Question:
The most effective treatment for eradication of group A streptococcus in
those who are apparent carriers is:
a single dose of intramuscular penicillin (Bicillin).
oral rifampin (Rifadin) for 4 days.
oral clindamycin (Cleocin) for 10 days. Correct
a single dose of intramuscular ceftriaxone (Rocephin).
, Explanation:
The most effective treatment for eradication of group A streptococcus in
those who are carriers is oral clindamycin (Cleocin) for 10 days. A single dose
of intramuscular penicillin (Bicillin) plus 4 days of oral rifampin (Rifadin) is
also effective.
9. Question:
The generic name for Dramamine is:
doxylamine.
diphenhydramine.
brompheniramine.
dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
10. Question:
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS)
who are allergic to penicillin, the best alternative first-line therapy is:
azithromycin (Zithromax).
clarithromycin (Biaxin).
doxycycline (Vibramycin). Correct
metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable
alternative for first-line therapy and can be used in patients with penicillin
allergy. A respiratory fluoroquinolone (levofloxacin 500 mg orally or
moxifloxacin 400 mg orally once daily) is another alternative for penicillin-
allergic patients. However, fluoroquinolones should be reserved for those
who have no alternative treatment options, because the serious adverse
effects associated with fluoroquinolones generally outweigh the benefits for
patients with acute sinusitis. Macrolides (clarithromycin or azithromycin),
Prescription Exam
1. Question:
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis,
should be administered:
with milk.
with meals.
on an empty stomach. Correct
with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1
hour prior to, or 2 hours after meals) to increase total absorption and with
adequate amount of fluid to reduce the risk of esophageal irritation and
ulceration. It should be administered at least 1 to 2 hours prior to, or 4 hours
after, an antacid containing aluminum and magnesium cations. It may
chelate with tetracycline (Sumycin) and reduce its total absorption. Serum
concentrations may be decreased if taken with dairy products.
2. Question:
The brand name for sulfacetamide ophthalmic is:
AzaSite.
Bleph-10. Correct
Besivance.
Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the
brand name of azithromycin. Besifloxacin is the generic name for Besivance.
The generic name of Garamycin is gentamicin sulfate.
3. Question:
The generic name for Polytrim ophthalmic is:
trimethoprim and polymyxin B. Correct
bacitracin/polymyxin B.
azithromycin.
besifloxacin.
,Explanation:
The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is
the brand name for bacitracin/polymyxin B. The brand name for azithromycin
is AzaSite. Besifloxacin brand name is Besivance.
4. Question:
Which of the following does NOT cause a drug-disease interaction when
using a decongestant/antihistamine medication such as
Naphazoline/pheniramine (Naphcon-A)?
Cardiovascular disease
Angle-closure glaucoma
Prostatic hypertrophy
Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-
A) include angle-closure glaucoma, MAOI inhibitor use within 14 days,
cardiovascular disease, hypertension, diabetes mellitus, prostatic
hypertrophy and urinary tract obstruction.
5. Question:
The maximum daily dose of acetaminophen for ages 12 years and older is:
1200 milligrams/day.
2000 milligrams/day.
3000 milligrams/day.
4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause
liver damage. Doses of 4000 mg (4 grams) per day should not be exceeded
in patients 12 years and older. Maximum dose in neonates is 60 mg/kg/day
and 75 mg/kg/day in infants and children.
6. Question:
,For treatment of blepharitis, patients should be instructed to apply
erythromycin ointment to the affected eye using:
a 0.5 inch ribbon 3 times daily for 5 days.
a 0.5 cm ribbon 3 times daily for 5 days.
a 1-inch ribbon 5 times daily for 7 days.
a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin
ophthalmic ointment up to 6 times daily for up to 10 days.
7. Question:
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is
indicated in the treatment of:
acute conjunctivitis.
vernal conjunctivitis. Correct
fungal keratitis.
herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control
allergic conditions. It is indicated in the treatment of vernal
keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. Vernal
conjunctivitis is long-term inflammation of the outer lining of the eyes. It is
due to an allergic reaction.
8. Question:
The most effective treatment for eradication of group A streptococcus in
those who are apparent carriers is:
a single dose of intramuscular penicillin (Bicillin).
oral rifampin (Rifadin) for 4 days.
oral clindamycin (Cleocin) for 10 days. Correct
a single dose of intramuscular ceftriaxone (Rocephin).
, Explanation:
The most effective treatment for eradication of group A streptococcus in
those who are carriers is oral clindamycin (Cleocin) for 10 days. A single dose
of intramuscular penicillin (Bicillin) plus 4 days of oral rifampin (Rifadin) is
also effective.
9. Question:
The generic name for Dramamine is:
doxylamine.
diphenhydramine.
brompheniramine.
dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
10. Question:
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS)
who are allergic to penicillin, the best alternative first-line therapy is:
azithromycin (Zithromax).
clarithromycin (Biaxin).
doxycycline (Vibramycin). Correct
metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable
alternative for first-line therapy and can be used in patients with penicillin
allergy. A respiratory fluoroquinolone (levofloxacin 500 mg orally or
moxifloxacin 400 mg orally once daily) is another alternative for penicillin-
allergic patients. However, fluoroquinolones should be reserved for those
who have no alternative treatment options, because the serious adverse
effects associated with fluoroquinolones generally outweigh the benefits for
patients with acute sinusitis. Macrolides (clarithromycin or azithromycin),
