AGNP BOARD EXAM QUESTIONS EYE EAR NOSE THROAT Prescription
(102 Questions)
Question:
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis, should be administered:
with milk.
with meals.
on an empty stomach. Correct
with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1 hour prior to, or 2
hours after meals) to increase total absorption and with adequate amount of fluid to reduce the
risk of esophageal irritation and ulceration. It should be administered at least 1 to 2 hours prior
to, or 4 hours after, an antacid containing aluminum and magnesium cations. It may chelate with
tetracycline (Sumycin) and reduce its total absorption. Serum concentrations may be decreased if
taken with dairy products.
Question:
The brand name for sulfacetamide ophthalmic is:
AzaSite.
Bleph-10. Correct
Besivance.
Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the brand name of
azithromycin. Besifloxacin is the generic name for Besivance. The generic name of Garamycin is
gentamicin sulfate.
Question:
The generic name for Polytrim ophthalmic is:
trimethoprim and polymyxin B. Correct
bacitracin/polymyxin B.
azithromycin.
besifloxacin.
Explanation:
,The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is the brand name for
bacitracin/polymyxin B. The brand name for azithromycin is AzaSite. Besifloxacin brand name
is Besivance.
Question:
Which of the following does NOT cause a drug-disease interaction when using a
decongestant/antihistamine medication such as Naphazoline/pheniramine (Naphcon-A)?
Cardiovascular disease
Angle-closure glaucoma
Prostatic hypertrophy
Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-A) include angle-
closure glaucoma, MAOI inhibitor use within 14 days, cardiovascular disease, hypertension,
diabetes mellitus, prostatic hypertrophy and urinary tract obstruction.
Question:
The maximum daily dose of acetaminophen for ages 12 years and older is:
1200 milligrams/day.
2000 milligrams/day.
3000 milligrams/day.
4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause liver damage.
Doses of 4000 mg (4 grams) per day should not be exceeded in patients 12 years and older.
Maximum dose in neonates is 60 mg/kg/day and 75 mg/kg/day in infants and children.
Question:
For treatment of blepharitis, patients should be instructed to apply erythromycin ointment to the
affected eye using:
a 0.5 inch ribbon 3 times daily for 5 days.
a 0.5 cm ribbon 3 times daily for 5 days.
, a 1-inch ribbon 5 times daily for 7 days.
a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin ophthalmic ointment up to
6 times daily for up to 10 days.
Question:
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is indicated in the
treatment of:
acute conjunctivitis.
vernal conjunctivitis. Correct
fungal keratitis.
herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control allergic conditions. It is
indicated in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal
keratitis. Vernal conjunctivitis is long-term inflammation of the outer lining of the eyes. It is due
to an allergic reaction.
Question:
The most effective treatment for eradication of group A streptococcus in those who are apparent
carriers is:
a single dose of intramuscular penicillin (Bicillin).
oral rifampin (Rifadin) for 4 days.
oral clindamycin (Cleocin) for 10 days. Correct
a single dose of intramuscular ceftriaxone (Rocephin).
Explanation:
The most effective treatment for eradication of group A streptococcus in those who are carriers is
oral clindamycin (Cleocin) for 10 days. A single dose of intramuscular penicillin (Bicillin) plus 4
days of oral rifampin (Rifadin) is also effective.
Question:
, The generic name for Dramamine is:
doxylamine.
diphenhydramine.
brompheniramine.
dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
Question:
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS) who are allergic to
penicillin, the best alternative first-line therapy is:
azithromycin (Zithromax).
clarithromycin (Biaxin).
doxycycline (Vibramycin). Correct
metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable alternative for
first-line therapy and can be used in patients with penicillin allergy. A respiratory
fluoroquinolone (levofloxacin 500 mg orally or moxifloxacin 400 mg orally once daily) is
another alternative for penicillin-allergic patients. However, fluoroquinolones should be reserved
for those who have no alternative treatment options, because the serious adverse effects
associated with fluoroquinolones generally outweigh the benefits for patients with acute sinusitis.
Macrolides (clarithromycin or azithromycin), trimethoprim-sulfamethoxazole, and second- or
third-generation cephalosporins are not recommended for empiric therapy because of high
resistance rates of S. pneumoniae.
Question:
Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is administered
orally:
based on weight twice daily for 5 days.
75 mg daily x 5 days.
75 mg twice daily x 5 days. Correct
(102 Questions)
Question:
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis, should be administered:
with milk.
with meals.
on an empty stomach. Correct
with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1 hour prior to, or 2
hours after meals) to increase total absorption and with adequate amount of fluid to reduce the
risk of esophageal irritation and ulceration. It should be administered at least 1 to 2 hours prior
to, or 4 hours after, an antacid containing aluminum and magnesium cations. It may chelate with
tetracycline (Sumycin) and reduce its total absorption. Serum concentrations may be decreased if
taken with dairy products.
Question:
The brand name for sulfacetamide ophthalmic is:
AzaSite.
Bleph-10. Correct
Besivance.
Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the brand name of
azithromycin. Besifloxacin is the generic name for Besivance. The generic name of Garamycin is
gentamicin sulfate.
Question:
The generic name for Polytrim ophthalmic is:
trimethoprim and polymyxin B. Correct
bacitracin/polymyxin B.
azithromycin.
besifloxacin.
Explanation:
,The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is the brand name for
bacitracin/polymyxin B. The brand name for azithromycin is AzaSite. Besifloxacin brand name
is Besivance.
Question:
Which of the following does NOT cause a drug-disease interaction when using a
decongestant/antihistamine medication such as Naphazoline/pheniramine (Naphcon-A)?
Cardiovascular disease
Angle-closure glaucoma
Prostatic hypertrophy
Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-A) include angle-
closure glaucoma, MAOI inhibitor use within 14 days, cardiovascular disease, hypertension,
diabetes mellitus, prostatic hypertrophy and urinary tract obstruction.
Question:
The maximum daily dose of acetaminophen for ages 12 years and older is:
1200 milligrams/day.
2000 milligrams/day.
3000 milligrams/day.
4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause liver damage.
Doses of 4000 mg (4 grams) per day should not be exceeded in patients 12 years and older.
Maximum dose in neonates is 60 mg/kg/day and 75 mg/kg/day in infants and children.
Question:
For treatment of blepharitis, patients should be instructed to apply erythromycin ointment to the
affected eye using:
a 0.5 inch ribbon 3 times daily for 5 days.
a 0.5 cm ribbon 3 times daily for 5 days.
, a 1-inch ribbon 5 times daily for 7 days.
a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin ophthalmic ointment up to
6 times daily for up to 10 days.
Question:
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is indicated in the
treatment of:
acute conjunctivitis.
vernal conjunctivitis. Correct
fungal keratitis.
herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control allergic conditions. It is
indicated in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal
keratitis. Vernal conjunctivitis is long-term inflammation of the outer lining of the eyes. It is due
to an allergic reaction.
Question:
The most effective treatment for eradication of group A streptococcus in those who are apparent
carriers is:
a single dose of intramuscular penicillin (Bicillin).
oral rifampin (Rifadin) for 4 days.
oral clindamycin (Cleocin) for 10 days. Correct
a single dose of intramuscular ceftriaxone (Rocephin).
Explanation:
The most effective treatment for eradication of group A streptococcus in those who are carriers is
oral clindamycin (Cleocin) for 10 days. A single dose of intramuscular penicillin (Bicillin) plus 4
days of oral rifampin (Rifadin) is also effective.
Question:
, The generic name for Dramamine is:
doxylamine.
diphenhydramine.
brompheniramine.
dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
Question:
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS) who are allergic to
penicillin, the best alternative first-line therapy is:
azithromycin (Zithromax).
clarithromycin (Biaxin).
doxycycline (Vibramycin). Correct
metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable alternative for
first-line therapy and can be used in patients with penicillin allergy. A respiratory
fluoroquinolone (levofloxacin 500 mg orally or moxifloxacin 400 mg orally once daily) is
another alternative for penicillin-allergic patients. However, fluoroquinolones should be reserved
for those who have no alternative treatment options, because the serious adverse effects
associated with fluoroquinolones generally outweigh the benefits for patients with acute sinusitis.
Macrolides (clarithromycin or azithromycin), trimethoprim-sulfamethoxazole, and second- or
third-generation cephalosporins are not recommended for empiric therapy because of high
resistance rates of S. pneumoniae.
Question:
Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is administered
orally:
based on weight twice daily for 5 days.
75 mg daily x 5 days.
75 mg twice daily x 5 days. Correct
