Pharm Exam 2 Questions
Chapter 15
Drugs Affecting the Central Nervous System MULTIPLE CHOICE
1. Sarah, a 42-year-old female, requests a prescription for an anorexiant to treat her obesity. A
trial of phentermine is prescribed. Prescribing precautions include:
A. Understanding that obesity is a contraindication to prescribing phentermine
B. Anorexiants may cause tolerance and should only be prescribed for 6 months
C. Patients should be monitored for postural hypotension
D. Renal function should be monitored closely while on anorexiants
ANS: B PTS: 1
2. Before prescribing phentermine to Sarah, a thorough drug history should be taken including
assessing for the use of serotonergic agents such as SSRIs and St John’s Wort due to:
A. Additive respiratory depression risk
B. Additive effects affecting liver function
C. The risk of serotonin syndrome
D. The risk of altered cognitive functioning
ANS: C PTS: 1
3. Antonia is a 3 year old who has a history of status epilepticus. Along with her routine
antiseizure medication, she should also have a home prescription for____ to be used for an
episode of status epilepticus.
A. IV phenobarbital
B. Rectal diazepam (Diastat)
C. IV phenytoin (Dilantin)
D. Oral carbamazepine (Tegretol)
ANS: B
4. Rabi is being prescribed phenytoin for seizures. Monitoring includes:
A
Assessing for phenytoin
hypersensitivity syndrome 3 to
8 weeks after starting
treatment
,B
Assessing for pedal edema
throughout therapy
C
Assessing heart rate at each
visit and consider altering
therapy if heart rate is less
than 60 bpm
D
Assessing for vision changes,
such as red- green blindness,
at least annually
ANS: A
5. Dwayne has recently started on carbamazepine to treat seizures. He
comes to see you and you note that while his carbamazepine levels had
been in the therapeutic range, they are now low. The possible cause for the
low carbamazepine levels include:
A Dwayne hasn’t been taking his carbamazepine because it causes
. insomnia
B Carbamazepine auto-induces metabolism, leading to lower levels in spite
. of good compliance
C Dwayne was not originally prescribed the correct amount of
. carbamazepine
D Carbamazepine is probably not the right antiseizure medication for
. Dwayne
ANS: B
, 6. Carbamazepine has a Black Box warning due to life-threatening:
A
Renal toxicity, leading to renal failure
.
B ANS: C
Hepatotoxicity, leading to liver failure
.
7. Long-
term
C Dermatologic reaction, including Steven’s Johnson and toxic
.A Routine
epidermal necrolysis
troponin levels to assess for cardiac
. damage
D
Cardiac effects, including supraventricular tachycardia
.B Annual eye examinations to assess for cataract
. development
monitoring of patients
who are taking
C Monthly pregnancy tests for all women of
carbamazepine includes:
. childbearing age
D
Complete blood count every 3 to 4 months
.
ANS: D
8. Six-year-old Lucy has recently been started on ethosuximide (Zarontin) for
seizures. She should be monitored for:
A Increased seizure activity, as this drug may auto-
. induce seizures
B
Altered renal function, including renal failure
.
C Blood dyscrasias, which are uncommon but
. possible