Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing Test Bank

Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
Test Bank

,Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
Test Bank




TestBank
toaccompany
Psychopharmacology,ThirdEdition
Meyer•Quenzer


Chapter1:PrinciplesofPharmacology

MultipleChoice

1. refer(s) to specific molecular changes that occur when a drug binds to
aparticulartargetsiteor receptor,while
aretheresultingwidespreadalterationsinfunction.
a. Drugaction;therapeuticeffects
b. Sideeffects;drugeffects
c. Therapeuticeffects; sideeffects
d. Drugaction; drugeffects
Answer:d
TextbookReference:Pharmacology:TheScience ofDrugAction

2. Afterdrugadministrationhasoccurred, theamount ofdruginthebloodthatisfreetobindat
specifictarget sites isreferred toas
a. thetherapeuticdose.
b. first-passeffects.
c. bioavailability.
d. ED50.
Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

3. Thespecificmolecularchangesthat occurwhena drugbinds toaparticulartarget
siteorreceptor arereferred to as
a. drugeffects.
b. drugaction.
c. sideeffects.
d. placeboeffects.
Answer:b
TextbookReference:Pharmacology: TheScienceofDrugAction

4. Whichofthefollowingisnot apossibleexplanation forplaceboeffects?
a. Pavlovianconditioning
b. Geneticvariation
c. Drugcompetition
d. Expectationofoutcome
Answer:c
TextbookReference:Pharmacology: TheScienceofDrugAction


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,Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
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5. The administrationofoxytocinhasbeenproposedas a treatmentforautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:c
TextbookReference:PharmacokineticFactors DeterminingDrugAction

6. Whichfactordoesnotaffectthepharmacokineticsofadrug?
a. Routeofadministration
b. Lipidsolubility
c. Depotbinding
d. Drugaction
Answer:d
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

7. First-passmetabolismoccurswhendrugsaretaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

8. Theareapostrema isone area inthebrain wherethe isnot complete.
a. cerebrospinalfluid
b. blood–brainbarrier
c. choroidplexus
d. phospholipidmembrane
Answer:b
TextbookReference:PharmacokineticFactorsDeterminingDrugAction

9. First-passmetabolism occurswithorallyadministereddrugsbecause
a. theirabsorption is slowed byfood.
b. drugsabsorbedintothe bloodstreamfromthestomachgoto theliveron
thewaytogeneralcirculation.
c. drugsmust firstsurvivetheacidic environmentof thestomach.
d. salivaryenzymesin themouth begintheprocessofmetabolism.
Answer:b
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

10. Toxicsubstances in theblood trigger avomitingresponse byactivatingthe
a. blood–brainbarrier.
b. choroidplexus.
c. areapostrema.
d. medianeminence.



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, Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
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Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

11. Drugsadministered_ havethemost rapidonset ofaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:d
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

12. Ionizationofadrugdependson the ofthe solution and the
ofthedrug.
a. pH;pKa
b. pKa;pH
c. concentration;lipid solubility
d. pH;concentration
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

13. Theabsorption ofadrugdependson all ofthefollowing except
a. lipidsolubility.
b. ionization.
c. bodytemperature.
d. theconcentrationofthedrug.
Answer:c
TextbookReference:PharmacokineticFactorsDeterminingDrugAction

14. Drugsthatare shouldbeavoided bywomen ofchildbearingage.
a. teratogenic
b. abletocrosstheplacental barrier
c. psychoactive
d. highlylipid-soluble
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

15. Agentsthatinducedevelopmentalabnormalitiesinafetusareknown as
a. psychoactivedrugs.
b. illicitdrugs.
c. teratogens.
d. placentaldrugs.
Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction

16. Depotbindingissaidtooccurwhendrugs
a. bindtotheirtargetsites.



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