UTERINE LEIOMYOMA
WHAT IS IT?
▪ Uterine leiomyomas, also known as a uterine fibroids
▪ Common benign tumors of smooth muscle cells or myometrium.
▪ Composed of smooth muscle that is replaced by fibrous (collagen and fibronectin) connecti
tissue
▪ Growth is promoted by estrogen
▪ Estrogen is the most important stimulus for leiomyoma growth
▪ Recent findings suggest that volume and growth of myomas are also heavily progesterone
dependent
▪ Distinct, firm and round
▪ Often occur in groups
▪ Classified according to location
▪ Intramural - within the muscular wall of uterus
▪ Subserous –on the outside surface of uterus
, ▪ Submucosal – on the inside of the uterus lining
▪ May be attached by stem, increased risk to torsion or infection)
▪ Can be located in cervix, or within ligaments
▪ Can detach from uterus, feeds of blood supply from abdominal organs