" **K**¥=#☒=§% É*¥ -55
HEE 'VE
¥±RAitF¥±4u
¥13.IT#En-Ai-FEIs.T4-
EFQFIA.FI#8EYttfFETnYE7EF-YH
45¥45 :-& #
¥zF¥¥¥fQT¥¥sH-9¥ :&
1=-1-8^17-9
:¥P¥[4¥☒F¥L¥Hx¥J :F☒'Ixt¥'¥H¥#5¥¥f¥ ¥¥
'
enrichment
E- separation
57¥ :* '¥ ¥ñ☒%¥s a
•
7 #iÉt%iFÉt¥F¥=Fki IFL :¥5¥s÷E , precipitation
•
t.FI/IY9A--EsT7-ExnEtx :¥☐¥.IT#-Ex5Eati:t-asoweni- extraction
☒ yyt-qpy.BY#GEhdtt=ETFdxcooy
1¥45 '¥¥¥
.
¥4s 3- EFE # ¥5 :-&
Be 'i¥☒5¥s :-&
ion exchange
chromatography
Recoery F¥É¥r+¥uTG☒ ¥4s :-& volatilization and
distillation
FREE # ¥+271T .
☒ 45¥ > 99.9% Uh ±
FREE 45¥11 0.01%-11 ☒ Tx "¥ :¥H?¥G ¥H¥ * F¥☐¥¥t¥¥E5¥=ñ
.IE/BnI#faFE5Eix
.
799% IT
4K¥ :-# < 0.011 .
☒ 295%51 4¥ t.EE#4tiFF=iTz:EEiFs:7--zIFEEHJ(01-17*2*-41 :ñ¥ÉEF¥
¥57T'J¥¥ER ¥4s :& phzh.naoti.BY#FHTIFhs3-:A1.2n.Cr.Sn.Pb,SbR:'FE¥
¥F¥QB¥s÷É
Ni.2n.cd.cu.lmgl-AITIE-H-%Ff-HHH.tt#
,
pHO-9.NHj.Ag.co ,
ADIGRAT IE.it#Pt.DDXIE-Ep7TY-fn- pH-s-b.ff-ttf-DF.li:5/f:E--.Al,FecW,TilwJ.ThlwJiBi...
#
-5 # ftp.ZEi-E-o#-5TA--ttrEE-*d.FI---.--Fo #11+74-9.8-14 B-ftp.t#B7A-Es3-tEtFHEExFH-rFti5Hp
'
, . # *nl¥¥☒EHt-953-17=-95
FAFARA.FI#ZKtFAGY4-Fx.4E-tIEA--E-*XTG--tn ¥-4 ?
-4B$ .TT#B-EkA-89BFtsT-tFFA=P-.hhKI' ¥1B '¥s
AS Hit .
¥¥¥xB¥shH5¥=¥F¥E¥
FIER # ¥417.91948b
'
* YE hydrophilic : ?¥ZT¥NbE4④ -4134¥
t bfkft.tn#Es-4-EEkLz;.-qyyr=
,
hydrophobic :# TREK# 1854$ .BR#I44-Ebt--f--ttx44--
,¥4 -4=257*12-9 FK fx-¥¥x Back extraction
4¥11.IT#E-txEA-EsD-t&-s-I44-9-E4bttIEnX4E .AE#-nIT-XF-fTtN-4A-i-t .
¥F¥xE9fx¥¥¥l 't-4%0--451419=4--12 :¥=¥☒f←¥ER¥J$
☒ A)
5¥28 "¥& -5 # ¥21b
.
FAE .
: water
-4-+1<-4*1--1 ,
organic -4187*12-4*4
¥É§¥ix partition coefficient
HAW) ← HAW)
¥771549975k ,
,
CHAI BEZ:-# 9¥
CHAIN
Ko :# ¥8 '¥¥ix ¥171T ¥F¥x
T¥ER¥h the percent extracted 45*218 distribution ratio
ÉF§¥TF*N¥A=☐#F¥E Mo covo HAW)← HALO)
f-
Katy t.EE/FslHAli
= =
=
☒ ☒ 9- ¥u¥¥ motmw covotcwvw
↳"w D ✗
R=¥
✗ HAD
= = ¥1,17 ftp.FHA.to HAN
colcwtvwlvo DTR .
9¥44 # ¥294.189
1¥ 12=1 D- f- D CHA , O CHATO ✗
HAD
✗ +1^-10
f-
,
=
D=
=
= K,
D -11 ✗
CHA ,w [HAJWXHA .w HAM
125¥41'kIetx☐* Fk :# 48=12--952 -1¥ D :#¥26b ¥44 '¥¥a
É¥aT¥¥¥x¥-H☐ ti*A=t8
t.it#tn-*FEx:KE-ix
1giR¥¥¥x
IE # vomttfkti.EE?i-YY-F-TE2VwmlttEEE#--t- mott.9-AFD.GG .
-
ik _¥+¥xf☐¥H¥ # 9- A #☒ Gattis '¥¥ -17mg
¥¥L#¥ "P¥
fFbB¥Ztb¥*p=§w=lM0
-
M) / V0 .
Vw
m, / Vw mimopvoeuw
¥4 #xnik.AE#F--J9'?----s ni.EE#TExh=yI-IF-ixEef
mn=M0(
Vw "
)
Mo -
Mn
f- =
pvotvw Mo
4¥28 :H☒☒¥¥¥¥AG¥É¥7¥D .BY:2#k-TExtb-ik-*+TExh=9-Ex9-t-q- Ex
a) IEE-txft.fi/7J:ItEq-=bz=R
HEE 'VE
¥±RAitF¥±4u
¥13.IT#En-Ai-FEIs.T4-
EFQFIA.FI#8EYttfFETnYE7EF-YH
45¥45 :-& #
¥zF¥¥¥fQT¥¥sH-9¥ :&
1=-1-8^17-9
:¥P¥[4¥☒F¥L¥Hx¥J :F☒'Ixt¥'¥H¥#5¥¥f¥ ¥¥
'
enrichment
E- separation
57¥ :* '¥ ¥ñ☒%¥s a
•
7 #iÉt%iFÉt¥F¥=Fki IFL :¥5¥s÷E , precipitation
•
t.FI/IY9A--EsT7-ExnEtx :¥☐¥.IT#-Ex5Eati:t-asoweni- extraction
☒ yyt-qpy.BY#GEhdtt=ETFdxcooy
1¥45 '¥¥¥
.
¥4s 3- EFE # ¥5 :-&
Be 'i¥☒5¥s :-&
ion exchange
chromatography
Recoery F¥É¥r+¥uTG☒ ¥4s :-& volatilization and
distillation
FREE # ¥+271T .
☒ 45¥ > 99.9% Uh ±
FREE 45¥11 0.01%-11 ☒ Tx "¥ :¥H?¥G ¥H¥ * F¥☐¥¥t¥¥E5¥=ñ
.IE/BnI#faFE5Eix
.
799% IT
4K¥ :-# < 0.011 .
☒ 295%51 4¥ t.EE#4tiFF=iTz:EEiFs:7--zIFEEHJ(01-17*2*-41 :ñ¥ÉEF¥
¥57T'J¥¥ER ¥4s :& phzh.naoti.BY#FHTIFhs3-:A1.2n.Cr.Sn.Pb,SbR:'FE¥
¥F¥QB¥s÷É
Ni.2n.cd.cu.lmgl-AITIE-H-%Ff-HHH.tt#
,
pHO-9.NHj.Ag.co ,
ADIGRAT IE.it#Pt.DDXIE-Ep7TY-fn- pH-s-b.ff-ttf-DF.li:5/f:E--.Al,FecW,TilwJ.ThlwJiBi...
#
-5 # ftp.ZEi-E-o#-5TA--ttrEE-*d.FI---.--Fo #11+74-9.8-14 B-ftp.t#B7A-Es3-tEtFHEExFH-rFti5Hp
'
, . # *nl¥¥☒EHt-953-17=-95
FAFARA.FI#ZKtFAGY4-Fx.4E-tIEA--E-*XTG--tn ¥-4 ?
-4B$ .TT#B-EkA-89BFtsT-tFFA=P-.hhKI' ¥1B '¥s
AS Hit .
¥¥¥xB¥shH5¥=¥F¥E¥
FIER # ¥417.91948b
'
* YE hydrophilic : ?¥ZT¥NbE4④ -4134¥
t bfkft.tn#Es-4-EEkLz;.-qyyr=
,
hydrophobic :# TREK# 1854$ .BR#I44-Ebt--f--ttx44--
,¥4 -4=257*12-9 FK fx-¥¥x Back extraction
4¥11.IT#E-txEA-EsD-t&-s-I44-9-E4bttIEnX4E .AE#-nIT-XF-fTtN-4A-i-t .
¥F¥xE9fx¥¥¥l 't-4%0--451419=4--12 :¥=¥☒f←¥ER¥J$
☒ A)
5¥28 "¥& -5 # ¥21b
.
FAE .
: water
-4-+1<-4*1--1 ,
organic -4187*12-4*4
¥É§¥ix partition coefficient
HAW) ← HAW)
¥771549975k ,
,
CHAI BEZ:-# 9¥
CHAIN
Ko :# ¥8 '¥¥ix ¥171T ¥F¥x
T¥ER¥h the percent extracted 45*218 distribution ratio
ÉF§¥TF*N¥A=☐#F¥E Mo covo HAW)← HALO)
f-
Katy t.EE/FslHAli
= =
=
☒ ☒ 9- ¥u¥¥ motmw covotcwvw
↳"w D ✗
R=¥
✗ HAD
= = ¥1,17 ftp.FHA.to HAN
colcwtvwlvo DTR .
9¥44 # ¥294.189
1¥ 12=1 D- f- D CHA , O CHATO ✗
HAD
✗ +1^-10
f-
,
=
D=
=
= K,
D -11 ✗
CHA ,w [HAJWXHA .w HAM
125¥41'kIetx☐* Fk :# 48=12--952 -1¥ D :#¥26b ¥44 '¥¥a
É¥aT¥¥¥x¥-H☐ ti*A=t8
t.it#tn-*FEx:KE-ix
1giR¥¥¥x
IE # vomttfkti.EE?i-YY-F-TE2VwmlttEEE#--t- mott.9-AFD.GG .
-
ik _¥+¥xf☐¥H¥ # 9- A #☒ Gattis '¥¥ -17mg
¥¥L#¥ "P¥
fFbB¥Ztb¥*p=§w=lM0
-
M) / V0 .
Vw
m, / Vw mimopvoeuw
¥4 #xnik.AE#F--J9'?----s ni.EE#TExh=yI-IF-ixEef
mn=M0(
Vw "
)
Mo -
Mn
f- =
pvotvw Mo
4¥28 :H☒☒¥¥¥¥AG¥É¥7¥D .BY:2#k-TExtb-ik-*+TExh=9-Ex9-t-q- Ex
a) IEE-txft.fi/7J:ItEq-=bz=R
