ATI Final Pharmacology Study Guide Solution. A+ Rated

lOMoAR cPSD|8470938 ATI Final Pharmacology guide solution lOMoAR cPSD|8470938 ATI Final Classification Prototype Action Uses Side effects Interactions NI Affecting NSAIDS NSAIDS: Asprin2nd Gen: Celecoxib (celebrex) decrease inflammation, Inflammation, Analgesia, fever GI discomfort, gastric Warfarin, Take with food, Pain and pain, and fever reduction, dysmenorrhea ulcers, bleeding, renal Glucocorticoids, milk, or fully inflammation dysfunction, Salicylism, Reye Syndrome Alcohol, Ibuprofen glass of water Antigout Colchicine decrease inflammation Gout GI toxicity Warfarin Pain and inflammation Migraine Medications Ergot alkaloids: Ergotamine (ergostat) Serotonin prevent inflammation abort acute migraine attack, Ergot: GI discomfort; Triptains with Avoid trigger Pain and receptor agonists (Triptains): Sumatripitan (Imitrex) and dilation to prevent migraines Ergotism, physical MAOI's factors. inflammation intracranial blood vessels dependence, abortionTriptans: Chest symptoms, angina, teratogenic Opioid Antagonist Naloxone (Narcan) interfere with the action of opioids opioid overdose, reverse effects of opioids, reversal of resp. tachycardia, tachypnea, abstinence syndrome Pain and inflammation depression in infants Neuromuscular Blocking Nondepolarizing: Tubocurarine (Tubarine) Block ACh at adjuncts to general anesthesia, Respiratory arrest, General anesthetics, continuous Nervous system Agents Depolarizing: succinylcholine (Anecitine) neuromuscular junction diagnosis myasthenia gravis, seizure control, endotracheal hypotentionSuccinylcholine: apnea, malignant Aminoglycosides, tetracyclines, cardiac monitoring intubation, endoscopy hypertension, hyperkalemia Cholinesterase inhibitors Anti Parkinsons Dopaminergic: Levodopa (Dopar, Larodopa) Dopamine agonists: pramipexole (Mirapex) Centrally block receptors Parkinsons Levodopa: N/V, Dyskinesias, ortho hypo, cardio effects, Levodopa: Protients, conventional effects may not be noticeable for Nervous system acting anticholengerics: Benztropine (congentin) Dopamine releaser (Antiviral): Amantadine psychosis, discoloration of sweat and urine, activation antipsychotic agents, pyridoxine, MAOIs. several weeks to months (symmetrel) of malignant melanoma Mirapex: sleep attacks, Mirapex: Levodopa daytime sleepiness, ortho hypo, psychosis, dyskinesias, NauseaCogentin: N/V, Atropine effects. AEDs Barbiturates: phenobarbital (Luminal) Hydantoins: slow entrance of Na and generalized seizures, partial CNS effects, skin rash, Dilantin: OC, use for control Nervous system phenytoin (Dilantin) Benzodiazepines: diazepam Ca, suppress neuronal seizures toxicity, Cardio effects, warfarin, not cure, seizure (valium), lorazepam (Ativan) Carbamazepine (Tegretol), ethosuximide (zaronin), valproic acid firing, inhibit GABA teratogenisis, GI effects, respiratory depression glucocorticoids, alcohol, valium. frequency chart (Depakote), gabapentin (Neurontin) Tegretol: OC, warfarin, grapefruit juice, phenytoin, phenobarbital. Muscle relaxants and Antispasmodics dantrolene (Dantrium) acts directly on spastic muscles relief of spasticity CNS depression, hepatic toxicity, physical CNS depressants don’t stop taking dependence medication Local Anesthetics Amide: lidocaine (xylocaine)"cain" decrease conduction of minor procedures... CNS excitation, Nervous system pain impulses Hypotension, Allergic reactions, Spinal headache, urinary retention General Inhalation Halothane (fluothane)"ane" loss of sensation, Surgery, diagnostic hypotension, resp and CNS depressants, NPO 6-8 hrs. Nervous system Anesthetics consciousness, memory loss procedures, analgesia, muscle relaxation cardio depression, malignant hyperthermia, CNS stimulants, morphine sulfate, before hepatotoxicity succinylcholine Antipsychotics -Conventional Low: Chlorpromazine (thorazine) High: Haloperidol inhibit psychotic schizo, bipolar, tourettes, EPS, TD, Neuroleptic Anticholinergic Nervous system (haldol) symptoms delusions, dementia, Huntington’s chorea malignant syndrome, Anticholinergic effects, agents, CNS depressants, ortho hypo, sedation, seizures, sexual dysfunction, Levodopa skin effects Antipsychotics -atypical clozapine (clozaril) blocks serotonin and severe schizo, psychosis Agranulocytosis, seizures, Immunosuppressive Nervous system dopamine weight gain, inflammation of heart muscle meds TCA amitriptyline (Elavil) block reuptake of norepi and serotonin -- intensify effects Depression, bipolar ortho hypo, anticholinergic effects, sedation, cardiac toxicity, MAOIs, Antihistamines, Epinephrine, NE, effects not experienced until 1-3 weeks Nervous system