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Case Study 1
An ABO group was performed on the cord blood of a full-term healthy infant. The mother
was O Rh negative. The following results were obtained:
Anti- Anti-B Anti- A cells B cells
A A,B
4+ 0 4+ 4+ 4+
QUESTIONS:
1. What is the ABO group of this baby? Explain your response.
In ABO blood grouping, the individual's plasma contains antibodies against the antigen
does not present in the red blood cells. Here, the cord blood of a full-term healthy infant
contains Anti-A antibody. So, the red blood cell must contain A antigen. The blood group
of the baby is therefore A positive.
2. Are any discrepancies noted in these results?
The test results also show the presence of A cells that would be the discrepancy in this
case study.
3. How does the test procedure vary from what you would expect for a newborn? Why?
The blood of newborn contains both A and B cells but only anti A antibody.
4. Does knowing the blood group of the mother help to explain the results?
, BLOOD BANK CASE STUDY QUESTIONS AND ANSWERS RATD A+
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The mother's blood group is O negative. So, she is homozygous for ABO antigen. The
blood group of newborn should contain at least one O antigen. The other antigen should
come from the father. Therefore, the newborn's blood group should be either AO or BO
but not AB. Reverse blood type of the mother’s.
5. The notation of AO represents a:
a. Bombay
phenotype b.
Genotype
c. Phenotype
d. Transferase