NURS 6501 Week 7 Knowledge Check
NURS 6501 Week 7 Knowledge Check
Question 1:
A 28-year-old woman presents to the clinic with a chief complaint of hirsutism and irregular
menses. She describes irregular and infrequent menses (five or six per year) since menarche
at 12 years of age. She began to develop dark, coarse facial hair when she was
14 years of age, but her parents did not seek treatment or medical opinion at that time. The
symptoms worsened after she gained weight in college. She got married 3 years ago and
has been trying to get pregnant for the last 2 years without success. Height 66 inches and
weight 198. BMI 32 kg.m2. Moderate hirsutism without virilization noted. Laboratory data
reveal CMP within normal limits (WNL), CBC with manual differential (WNL), TSH 0.9 IU/L SI
units (normal 0.4-4.0 IU/L SI units), a total testosterone of 65 ng/dl (normal 2.4-
47 ng/dl), and glycated hemoglobin level of 6.1% (normal value ≤5.6%). Based on this
information, the APRN diagnoses the patient with polycystic ovarian syndrome (PCOS) and
refers her to the Women’s Health APRN for further workup and management.
Question 1 of 2:
What is the pathogenesis of PCOS?
Answer:
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to
20% of reproductive aged women are affected. PCOS presents as a phenotype
reflecting a self-perpetuating vicious cycle involving neuroendocrine, metabolic, and
ovarian dysfunction. PCOS reflects the interactions among multiple proteins and genes
influenced by epigenetic and environmental factors. Functional ovarian
hyperandrogenism due to ovarian steroidal dysregulation is at the center of the
pathogenesis of polycystic ovary syndrome. Functional ovarian hyperandrogenism due
to ovarian steroidal dysregulation is at the center of the pathogenesis of polycystic ovary
syndrome. This has both genetic and environmental factors. The genetic factors are
polycystic ovary morphology, insulin resistance, hyperandrogenemia, defects in insulin
secretion. The steroidal dysregulation may lead to anovulation, irregular menses,
virilization, hirsutism and infertility. Insulin resistance may also occur.
How does PCOS affect a woman’s fertility or infertility?
Answer:
Women with PCOS have hormonal imbalances showing increased levels of
testosterone. This hormonal imbalance prevents development and release of mature
, NURS 6501 Week 7 Knowledge Check
eggs. This prevents ovulation thus preventing pregnancy to occur.
Question 2:
NURS 6501 Week 7 Knowledge Check
Question 1:
A 28-year-old woman presents to the clinic with a chief complaint of hirsutism and irregular
menses. She describes irregular and infrequent menses (five or six per year) since menarche
at 12 years of age. She began to develop dark, coarse facial hair when she was
14 years of age, but her parents did not seek treatment or medical opinion at that time. The
symptoms worsened after she gained weight in college. She got married 3 years ago and
has been trying to get pregnant for the last 2 years without success. Height 66 inches and
weight 198. BMI 32 kg.m2. Moderate hirsutism without virilization noted. Laboratory data
reveal CMP within normal limits (WNL), CBC with manual differential (WNL), TSH 0.9 IU/L SI
units (normal 0.4-4.0 IU/L SI units), a total testosterone of 65 ng/dl (normal 2.4-
47 ng/dl), and glycated hemoglobin level of 6.1% (normal value ≤5.6%). Based on this
information, the APRN diagnoses the patient with polycystic ovarian syndrome (PCOS) and
refers her to the Women’s Health APRN for further workup and management.
Question 1 of 2:
What is the pathogenesis of PCOS?
Answer:
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to
20% of reproductive aged women are affected. PCOS presents as a phenotype
reflecting a self-perpetuating vicious cycle involving neuroendocrine, metabolic, and
ovarian dysfunction. PCOS reflects the interactions among multiple proteins and genes
influenced by epigenetic and environmental factors. Functional ovarian
hyperandrogenism due to ovarian steroidal dysregulation is at the center of the
pathogenesis of polycystic ovary syndrome. Functional ovarian hyperandrogenism due
to ovarian steroidal dysregulation is at the center of the pathogenesis of polycystic ovary
syndrome. This has both genetic and environmental factors. The genetic factors are
polycystic ovary morphology, insulin resistance, hyperandrogenemia, defects in insulin
secretion. The steroidal dysregulation may lead to anovulation, irregular menses,
virilization, hirsutism and infertility. Insulin resistance may also occur.
How does PCOS affect a woman’s fertility or infertility?
Answer:
Women with PCOS have hormonal imbalances showing increased levels of
testosterone. This hormonal imbalance prevents development and release of mature
, NURS 6501 Week 7 Knowledge Check
eggs. This prevents ovulation thus preventing pregnancy to occur.
Question 2:
