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Clinical Practice Guidelines Hypertension
NR 511 Differential Diagnosis and Primary Care 19 June 2019
,NR 511 DIFFERENTIAL DIAGNOSIS AND PRIMARY CARE RATE
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Pathophysiology
• Hypertension is considered the condition when the blood flows through the blood vessels with a force greater
than normal.
• Hypertension can strain the heart, damage blood vessels, and increase your risk of heart attack, stroke, kidney
disease, and death.
• Hypertension is caused by increases in cardiac output or total peripheral resistance, or both. There is many factors
affecting cardiac output and peripheral resistance which include genetics and physiologic mechanisms.
• Cardiac output is increased by any condition that increases heart rate or stroke volume, whereas peripheral
resistance is increased by any factor that increases blood viscosity or reduces vessel diameter.
, NR 511 DIFFERENTIAL DIAGNOSIS AND PRIMARY CARE RATE
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Incident and Prevalence
• Prevalence of High Blood Pressure (HBP): 46% of U.S. Adults vs. 36% based on JNC 7 definition.
• During 2015–2016, the prevalence of hypertension was 29.0% and increased with age: age group 18–39, 7.5%; 40–59,
33.2%; and 60 and over, 63.1%.
• Most people between 130-139 mmHg SBP or 80-89 mmHg DBP will NOT require medication.
• According to the CDC about 1 of 3 U.S. adults or about 75 million people have high blood pressure and only about (54%)
of these people have their high blood pressure under control.
• The number of visits to the physician offices with essential hypertension as their primary diagnosis is 42.7 million.
• High blood pressure was a primary contributing cause death for more than 410,000 Americans in 2014, that’s more
than 1,100 deaths each day.
American College of Cardiology/Am
Association Whelton PK et al, JACC
2018