NUR 2474 Pharm Module 2 Quiz
S/S of Alzheimers Disease? - answer memory loss, confusion, feeling disoriented,
impaired judgement, inability to self care, cannot do ADLs
What is happening in the brain before one begins medication with Alzheimers? - answer
there is reduced Ach or cholinergic transmission with levels below 90%, the neurons are
degenerated.
Main medication given for Alzheimers disease? - answer donepezil
What is the prognosis with Alzheimers? - answer it is irreversible and incurable, but
medication use can slow its progression
What does donepezil do? - answer prevent Ach breakdown at the neural level, therefor
increasing concentration of the neurotransmitter available for reuptake.
SE of donepezil? - answer HA, dizziness, GI effects- N,V, bronchoconstriction
What is one thing we need to teach the patient and family about use of the medication
donepezil? - answer remember to take the medication on time and to follow correct
dose. often times patient who take this drug may forget to take it or that they have
already taken it, so having a supportive person will help with management.
S/S of Parkinson's - answer dyskinesia, tremors, rigidity, postural instability,
bradykinesia, mask like face, shifting gait, pill rolling movements, autonomic
disturbance, depression and psychosis.
What is happening in the brain before one begins medication with Parkinsons? - answer
There is a low amount of dopamine, and increase Ach stimulation of GABA
Main medications for Parkinsons - answer Levodopa/Carbidopa
selegiline
Lasting effects of levodopa/carbidopa over time - answer lasts 2-5 years then will wear
off over time
Why is levodopa used with carbidopa? - answer enhances the effects of levodopa and
helps reduce N and V associated.
How does levodopa/carbidopa work? - answer increases dopamine synthesis at the
BBB that is converted to dopamine and is then reuptaked. carbidopa has no effects.
SE levodopa/carbidopa - answer N,V,postural hypotension, increase Na and water,
CNS effects, anxiety, cognitive impairment, insomnia, nightmares, behavior changes.
Toxicity SE levodopa/carbidopa - answer psychosis, vital hallucinations, vivid dreams,
nightmares, paranoia- too much dopamine in the brain
S/S of Alzheimers Disease? - answer memory loss, confusion, feeling disoriented,
impaired judgement, inability to self care, cannot do ADLs
What is happening in the brain before one begins medication with Alzheimers? - answer
there is reduced Ach or cholinergic transmission with levels below 90%, the neurons are
degenerated.
Main medication given for Alzheimers disease? - answer donepezil
What is the prognosis with Alzheimers? - answer it is irreversible and incurable, but
medication use can slow its progression
What does donepezil do? - answer prevent Ach breakdown at the neural level, therefor
increasing concentration of the neurotransmitter available for reuptake.
SE of donepezil? - answer HA, dizziness, GI effects- N,V, bronchoconstriction
What is one thing we need to teach the patient and family about use of the medication
donepezil? - answer remember to take the medication on time and to follow correct
dose. often times patient who take this drug may forget to take it or that they have
already taken it, so having a supportive person will help with management.
S/S of Parkinson's - answer dyskinesia, tremors, rigidity, postural instability,
bradykinesia, mask like face, shifting gait, pill rolling movements, autonomic
disturbance, depression and psychosis.
What is happening in the brain before one begins medication with Parkinsons? - answer
There is a low amount of dopamine, and increase Ach stimulation of GABA
Main medications for Parkinsons - answer Levodopa/Carbidopa
selegiline
Lasting effects of levodopa/carbidopa over time - answer lasts 2-5 years then will wear
off over time
Why is levodopa used with carbidopa? - answer enhances the effects of levodopa and
helps reduce N and V associated.
How does levodopa/carbidopa work? - answer increases dopamine synthesis at the
BBB that is converted to dopamine and is then reuptaked. carbidopa has no effects.
SE levodopa/carbidopa - answer N,V,postural hypotension, increase Na and water,
CNS effects, anxiety, cognitive impairment, insomnia, nightmares, behavior changes.
Toxicity SE levodopa/carbidopa - answer psychosis, vital hallucinations, vivid dreams,
nightmares, paranoia- too much dopamine in the brain
