TEST BANK PATHOPHYSIOLOGY THE
BIOLOGIC BASIS FOR DISEASE IN ADULTS
PATHOPHYSIOL
AND CHILDREN 8th Edition, A guide.
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BIOLOGIC BASIS
FOR DISEASE IN
ADULTS AND
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TEST BANK
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND
CHILDREN
8th Edition
Kathryn L. McCance, Sue E. Huether
Contents
Chapter 01: Cellular Biology
• Which statement best describes the cellular function of metabolic absorption?
• Cells can produce proteins.
• Cells can secrete digestive enzymes.
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• Cells can take in and use nutrients.
• Cells can synthesize fats.
AN
S:
C
In metabolic absorption, all cells take in and use nutrients and other
substances from their surroundings. The remaining options are not inclusive
in their descriptions of cellular metabolicabsorption.
PTS: 1 DIF: Cognitive Level: Remembering
• Where is most of a cell’s genetic information, including RNA and DNA, contained?
• Mitochondria
• Ribosome
• Nucleolus
• Lysosome
AN
S:
C
The nucleus contains the nucleolus, a small dense structure composed largely
of RNA, most ofthe cellular DNA, and the DNA-binding proteins, such as
the histones, which regulate its activity. The mitochondria are responsible for
cellular respiration and energy production.
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
function
as the intracellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
• Which component of the cell produces hydrogen peroxide (H2O2) by
using oxygen to removehydrogen atoms from specific substrates in an
oxidative reaction?
• Lysosomes
• Peroxisomes
• Ribosomes
• Endosome
AN
S:
B
Peroxisomes are so named because they usually contain enzymes that use
oxygen to remove hydrogen atoms from specific substrates in an oxidative
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reaction that produces H2O2, which is apowerful oxidant and potentially
destructive if it accumulates or escapes from peroxisomes.
Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized
in the nucleolus and secreted into the cytoplasm through pores in the nuclear
envelope called nuclear pore complexes. Lysosomes are saclike structures
that originate from the Golgi complex and containmore than 40 digestive
enzymes called hydrolases, which catalyze bonds in proteins, lipids, nucleic
acids, and carbohydrates. An endosome is a vesical that has been pinched off
from the cellular membrane.
PTS: 1 DIF: Cognitive Level: Remembering
• Which cell component is capable of cellular autodigestion when it is released during cell
injury?
• Ribosome
• Golgi complex
• Smooth endoplasmic reticulum
• Lysosomes
ANS: D
The lysosomal membrane acts as a protective shield between the powerful
digestive enzymes within the lysosome and the cytoplasm, preventing their
leakage into the cytoplasmic matrix. Disruption of the membrane by various
treatments or cellular injury leads to a release of the lysosomal enzymes,
which can then react with their specific substrates, causing cellular self-
digestion. The chief function of a ribosome is to provide sites for cellular
protein synthesis. TheGolgi complex is a network of flattened, smooth
vesicles and membranes often located near the cell nucleus. The smooth
endoplasmic reticulum is involved in steroid hormone production and
removing toxic substances from the cell.
PTS: 1 DIF: Cognitive Level: Remembering
• Which cAMP-mediated response is related to antidiuretic hormone?
• Increased heart rate and force of contraction
• Secretion of cortisol
• Increased retention of water
• Breakdown of fat
ANS: C
Antidiuretic hormone leads to increased retention of water in the body.
Epinephrine causes increases in heart rate and force of contraction. Increased
cortisol secretion is due to ACTH.Breakdown of fat is due to glucagon.
PTS: 1 DIF: Cognitive Level: Remembering
• During which phase of the cell cycle is DNA synthesized?
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