Pharmacotherapeutics for Advanced Practice Nurse Midterm.
1. A19-year-old male was started on risperidone. Monitoring for 1
risperidone includes observing for common side effects,
including:
1. Bradykinesia, akathisia, and agitation
2. Excessive weight gain
3. Hypertension
4. Potentially fatal agranulocytosis
2. A66-year-old male was prescribed phenelzine (Nardil) while in 4
an acute psychiatric unit for recalcitrant depression. The NP
managing his primary health care needs to understand the
following regarding phenelzine and other monoamine oxidase
inhibitors (MAOIs):
1. He should not be prescribed any serotonergic drug such as
sumatriptan (Imitrex)
2. MAOIs interact with many common foods, including
yogurt, sour cream, and soy sauce
3. Symptoms of hypertensive crisis (headache, tachycardia,
sweating) require immediate treatment
4. All of the above
3. Abrupt withdrawal of beta blockers can be life threatening. 3
Patients at highest risk for serious consequences of rapid
withdrawal are those with:
1. Angina
2. Coronary artery disease
3. Both 1 and 2
4. Neither 1 nor 2
4. Anacceptable first-line treatment for peptic ulcer disease with 3
positive H. pylori test is:
1. Histamine2 receptor antagonists for 4 to 8 weeks
2. Proton pump inhibitor bid for 12 weeks until healing
is complete
, 3. Proton pump inhibitor bid plus clarithromycin
plus amoxicillin for 14 days
4. Proton pump inhibitor bid and levofloxacin for 14 days
5. According to the National Standards of Culturally and 3
Linguistically Appropriate Services, an interpreter for health
care:
1. May be a bilingual family member
2. May be a bilingual nurse or other health-care provider
3. Must be a professionally trained medical interpreter
4. Must be an employee of the organization
6. According to the U.S. Office of Minority Health, poor health 4
outcomes among African Americans are attributed to:
1. The belief among African Americans that prayer is
more powerful than drugs
2. Poor compliance on the part of the African American patient
3. The genetic predisposition for illness found among African
Americans
4. Discrimination, cultural barriers, and lack of access
to health care
7. According to traditional Chinese medicine, if a person who has 1
a fever is given a herb that is yang in nature, such as
golden seal, the patient's illness will:
1. Get worse
2. Get better
3. Not be adequately treated
4. Need additional herbs to treat the yan
8. An ACE inhibitor and what other class of drug may reduce 3
proteinuria in patients with diabetes better than either drug
alone?
1. Beta blockers
2. Diuretics
, 3. Nondihydropyridine calcium channel blockers
4. Angiotensin II receptor blockers
9. ACE inhibitors are a foundational medication in HF. Which 4
group of patients cannot take them safely?
1. Elderly patients with reduced renal clearance
2. Pregnant women
3. Women under age 30
4. 1 and 2
10. ACE inhibitors are contraindicated in pregnancy. While 3
treatment of heart failure during pregnancy is best done by
a specialist, which of the following drug classes is considered
to be safe, at least in the later parts of pregnancy?
1. Diuretics
2. ARBs
3. Beta blockers
4. Nitrates
11. Actions taken to reduce drug—drug interaction problems 3
include all of the following EXCEPT:
1. Reducing the dosage of one of the drugs
2. Scheduling their administration at different times
3. Prescribing a third drug to counteract the adverse
reaction of the combination
4. Reducing the dosage of both drugs
12. Activation of central alpha2 receptors results in inhibition of 2
cardioacceleration and centers in the brain.
1. Vasodilation
2. Vasoconstriction
3. Cardiovascular
, 4. Respiratory
13. Adherence is improved when a drug can be given once daily. 2
Which of the following drugs can be given once daily?
1. Tacrine
2. Donepezil
3. Memantine
4. Pyridostigmine
14. Adherence to beta blocker therapy may be affected by their: 3
1. Short half-lives requiring twice daily dosing
2. Tendency to elevate lipid levels
3. Effects on the male genitalia, which may produce impotence
4. None of the above
15. An advantage of prescribing a sublingual medication is that 1
the medication is:
1. Absorbed rapidly
2. Excreted rapidly
3. Metabolized minimally
4. Distributed equally
16. After H. pylori treatment is completed, the next step in peptic 3
ulcer disease therapy is:
1. Testing for H. pylori eradication with a serum ELISA test
2. Endoscopy by a specialist
3. A proton pump inhibitor for 8 to 12 weeks until healing is
complete
4. All of the above
17. An agonist activates a receptor and stimulates a response. 4
When given frequently over time, the body may:
1. Upregulate the total number of receptors
1. A19-year-old male was started on risperidone. Monitoring for 1
risperidone includes observing for common side effects,
including:
1. Bradykinesia, akathisia, and agitation
2. Excessive weight gain
3. Hypertension
4. Potentially fatal agranulocytosis
2. A66-year-old male was prescribed phenelzine (Nardil) while in 4
an acute psychiatric unit for recalcitrant depression. The NP
managing his primary health care needs to understand the
following regarding phenelzine and other monoamine oxidase
inhibitors (MAOIs):
1. He should not be prescribed any serotonergic drug such as
sumatriptan (Imitrex)
2. MAOIs interact with many common foods, including
yogurt, sour cream, and soy sauce
3. Symptoms of hypertensive crisis (headache, tachycardia,
sweating) require immediate treatment
4. All of the above
3. Abrupt withdrawal of beta blockers can be life threatening. 3
Patients at highest risk for serious consequences of rapid
withdrawal are those with:
1. Angina
2. Coronary artery disease
3. Both 1 and 2
4. Neither 1 nor 2
4. Anacceptable first-line treatment for peptic ulcer disease with 3
positive H. pylori test is:
1. Histamine2 receptor antagonists for 4 to 8 weeks
2. Proton pump inhibitor bid for 12 weeks until healing
is complete
, 3. Proton pump inhibitor bid plus clarithromycin
plus amoxicillin for 14 days
4. Proton pump inhibitor bid and levofloxacin for 14 days
5. According to the National Standards of Culturally and 3
Linguistically Appropriate Services, an interpreter for health
care:
1. May be a bilingual family member
2. May be a bilingual nurse or other health-care provider
3. Must be a professionally trained medical interpreter
4. Must be an employee of the organization
6. According to the U.S. Office of Minority Health, poor health 4
outcomes among African Americans are attributed to:
1. The belief among African Americans that prayer is
more powerful than drugs
2. Poor compliance on the part of the African American patient
3. The genetic predisposition for illness found among African
Americans
4. Discrimination, cultural barriers, and lack of access
to health care
7. According to traditional Chinese medicine, if a person who has 1
a fever is given a herb that is yang in nature, such as
golden seal, the patient's illness will:
1. Get worse
2. Get better
3. Not be adequately treated
4. Need additional herbs to treat the yan
8. An ACE inhibitor and what other class of drug may reduce 3
proteinuria in patients with diabetes better than either drug
alone?
1. Beta blockers
2. Diuretics
, 3. Nondihydropyridine calcium channel blockers
4. Angiotensin II receptor blockers
9. ACE inhibitors are a foundational medication in HF. Which 4
group of patients cannot take them safely?
1. Elderly patients with reduced renal clearance
2. Pregnant women
3. Women under age 30
4. 1 and 2
10. ACE inhibitors are contraindicated in pregnancy. While 3
treatment of heart failure during pregnancy is best done by
a specialist, which of the following drug classes is considered
to be safe, at least in the later parts of pregnancy?
1. Diuretics
2. ARBs
3. Beta blockers
4. Nitrates
11. Actions taken to reduce drug—drug interaction problems 3
include all of the following EXCEPT:
1. Reducing the dosage of one of the drugs
2. Scheduling their administration at different times
3. Prescribing a third drug to counteract the adverse
reaction of the combination
4. Reducing the dosage of both drugs
12. Activation of central alpha2 receptors results in inhibition of 2
cardioacceleration and centers in the brain.
1. Vasodilation
2. Vasoconstriction
3. Cardiovascular
, 4. Respiratory
13. Adherence is improved when a drug can be given once daily. 2
Which of the following drugs can be given once daily?
1. Tacrine
2. Donepezil
3. Memantine
4. Pyridostigmine
14. Adherence to beta blocker therapy may be affected by their: 3
1. Short half-lives requiring twice daily dosing
2. Tendency to elevate lipid levels
3. Effects on the male genitalia, which may produce impotence
4. None of the above
15. An advantage of prescribing a sublingual medication is that 1
the medication is:
1. Absorbed rapidly
2. Excreted rapidly
3. Metabolized minimally
4. Distributed equally
16. After H. pylori treatment is completed, the next step in peptic 3
ulcer disease therapy is:
1. Testing for H. pylori eradication with a serum ELISA test
2. Endoscopy by a specialist
3. A proton pump inhibitor for 8 to 12 weeks until healing is
complete
4. All of the above
17. An agonist activates a receptor and stimulates a response. 4
When given frequently over time, the body may:
1. Upregulate the total number of receptors
