Biochem C785 - WGU - Module 2 - All
Questions And Answers Latest Solution
Deedra's dad has Alzheimer's Disease (AD) which is caused by a change in protein structure
Correct Answer: True
Alzheimer's disease is caused by aggregation of the Amyloid beta peptide and tangle formation by
the tau protein. What kinds of amino acids are likely to drive the formation of these protein
aggregates?
Correct Answer: hydrophobic
After learning about Alzheimer's disease and one of the drugs used in its treatment, what other drug
design strategies could you use to offer treatment for AD?
Correct Answer: 1. Drugs that break up the amyloid plaques
2. Drugs that block the production of amyloid beta peptide
3. drugs that inhibits the aggregation of protein structures
A substrate binds to an enzyme at a specific site is referred to as
Correct Answer: an active site
You are in charge of designing a drug that inhibits the activity of a specific enzyme. An important
criteria for the drug selection is to ensure that the drug is directly in competition with the original
substrate when binding to the active site of the enzyme. What inhibitor would be an ideal choice?
Correct Answer: A competitive inhibitor
These factors can affect the protein folding and activity of an enzyme:
Correct Answer: 1. pH
2. Heat
3. Reducing agents
One way a cell can avoid overproduction of a molecule is by using a particular type of inhibition in
which the molecule itself acts as an inhibitor for an enzyme in its production pathway. This type of
regulation is known as feedback inhibition
Correct Answer: True
What type of enzyme adds a phosphate to another molecule?
Correct Answer: Kinase
What are possible effects that phosphorylation/dephosphorylation can have on the activity of an
enzyme?
Correct Answer: 1. turn the enzyme on
2. turn the enzyme off
Questions And Answers Latest Solution
Deedra's dad has Alzheimer's Disease (AD) which is caused by a change in protein structure
Correct Answer: True
Alzheimer's disease is caused by aggregation of the Amyloid beta peptide and tangle formation by
the tau protein. What kinds of amino acids are likely to drive the formation of these protein
aggregates?
Correct Answer: hydrophobic
After learning about Alzheimer's disease and one of the drugs used in its treatment, what other drug
design strategies could you use to offer treatment for AD?
Correct Answer: 1. Drugs that break up the amyloid plaques
2. Drugs that block the production of amyloid beta peptide
3. drugs that inhibits the aggregation of protein structures
A substrate binds to an enzyme at a specific site is referred to as
Correct Answer: an active site
You are in charge of designing a drug that inhibits the activity of a specific enzyme. An important
criteria for the drug selection is to ensure that the drug is directly in competition with the original
substrate when binding to the active site of the enzyme. What inhibitor would be an ideal choice?
Correct Answer: A competitive inhibitor
These factors can affect the protein folding and activity of an enzyme:
Correct Answer: 1. pH
2. Heat
3. Reducing agents
One way a cell can avoid overproduction of a molecule is by using a particular type of inhibition in
which the molecule itself acts as an inhibitor for an enzyme in its production pathway. This type of
regulation is known as feedback inhibition
Correct Answer: True
What type of enzyme adds a phosphate to another molecule?
Correct Answer: Kinase
What are possible effects that phosphorylation/dephosphorylation can have on the activity of an
enzyme?
Correct Answer: 1. turn the enzyme on
2. turn the enzyme off
