NR 565Midterm Study Guide
NR565 Week 4 Study Guide Week 4 is the midterm (no quiz) and includes all
material from Weeks 1-4; Be sure to also review the Weeks 1, 2 & 3 study
guides to prepare for the exam Many questions will are written to assess
your clinical application of the material from the textbook, in real-world
scenarios
Chapter 15: Drugs Affecting the Central Nervous System
Anorexiants: phentermine/Adipex, benzphetamine/Didrex, diethylpropion
HCL/Tenuate, phendimetrazine/Bontril, lorcaserin/Belviq. Precautions and
contraindications-use with caution in diabetics and individuals with
substance abuse, do not prescribe with MAOs (HTN crisis), or serotonin
(serotonin syndrome)
Anticonvulsants: phenobarbital, Depakote, gabapentin, valproates,
lamotrigine. (all can increase S/S)
Hydantoins-phenytoin/Dilantin, ethotoin/Peganone, osohentoin/Cerebyx-1st
line of defense for clonic-tonic working on the motor cortex to slow abnormal
charges. ADRs- phenytoin induced HEP, cardiovascular reactions to fast IV
push, contraindicated for brady, blocks, strokes- (assess for fever, rash,
lymphadenopathy) do not stop abruptly/monitor blood levels
Iminostilbenes-carbamazepine/Tegretol, oxcarbazepine/Trileptal, treats
epilepsy, bipolar, aggressive disorders reducing abnormal activity-slows
influx of sodium in cortical neurons-contraindicated for bone marrow
suppression, No grapefruit juice MAOs, Preg D, BBW-Steven’s John
Syndrome/toxic necrolysis in Chinese/blood dycrasias-monitor blood
levels/decrease effectiveness of oral contraceptives Succinimides-
ethosuximide/Zarontin, methsuximide/Celontin-treats absence seizure by
decreasing nerve impulses in the motor cortex-ADRs-GI upset take with
food, avoid ETOH--(monitor blood levels)
Drugs that affect GABA: benzodiazepines, gabapentin/Neurontin,
topiramate/Topamax, tiagabine/Gabitril- monitor S/I, weight, ability to sweat,
bicarbonate levels, and seizure activity- may cause false+ urine protein,
somnolence, and dizziness
Antidepressants: TCAs, SSRIs, MAOIs, SNRIs, miscellaneous (S/I BBW
all) All Metabolized in the liver
Monoamine Oxidase Inhibitors (MAOIs): phenelzine/Nardil,
isocarboxazid/Marplan, tranylcypromine/Parnate, selegiline/Emsam- 1st
generation, blocks metabolizing enzymes on dopamine, norepinephrine,
serotonin. Fast acting within 2 weeks.
Contraindication includes liver disease, CHF, SRI, SNRI. Avoid tyramine and
This study source was downloaded by 100000848398116 from CourseHero.com on 06-07-2022 10:00:32 GMT -05:00
https://www.coursehero.com/file/77284856/Midterm-Study-Guidedocx/
, NR 565Midterm Study Guide
all food and drugs that could raise BP, no chocolate, caffeine, yogurt, sour
cream, aged meat, and cheese. HTN crisis symptoms include palpitations,
stiff neck, headache, chest tightness, and tachycardia.
This study source was downloaded by 100000848398116 from CourseHero.com on 06-07-2022 10:00:32 GMT -05:00
https://www.coursehero.com/file/77284856/Midterm-Study-Guidedocx/
NR565 Week 4 Study Guide Week 4 is the midterm (no quiz) and includes all
material from Weeks 1-4; Be sure to also review the Weeks 1, 2 & 3 study
guides to prepare for the exam Many questions will are written to assess
your clinical application of the material from the textbook, in real-world
scenarios
Chapter 15: Drugs Affecting the Central Nervous System
Anorexiants: phentermine/Adipex, benzphetamine/Didrex, diethylpropion
HCL/Tenuate, phendimetrazine/Bontril, lorcaserin/Belviq. Precautions and
contraindications-use with caution in diabetics and individuals with
substance abuse, do not prescribe with MAOs (HTN crisis), or serotonin
(serotonin syndrome)
Anticonvulsants: phenobarbital, Depakote, gabapentin, valproates,
lamotrigine. (all can increase S/S)
Hydantoins-phenytoin/Dilantin, ethotoin/Peganone, osohentoin/Cerebyx-1st
line of defense for clonic-tonic working on the motor cortex to slow abnormal
charges. ADRs- phenytoin induced HEP, cardiovascular reactions to fast IV
push, contraindicated for brady, blocks, strokes- (assess for fever, rash,
lymphadenopathy) do not stop abruptly/monitor blood levels
Iminostilbenes-carbamazepine/Tegretol, oxcarbazepine/Trileptal, treats
epilepsy, bipolar, aggressive disorders reducing abnormal activity-slows
influx of sodium in cortical neurons-contraindicated for bone marrow
suppression, No grapefruit juice MAOs, Preg D, BBW-Steven’s John
Syndrome/toxic necrolysis in Chinese/blood dycrasias-monitor blood
levels/decrease effectiveness of oral contraceptives Succinimides-
ethosuximide/Zarontin, methsuximide/Celontin-treats absence seizure by
decreasing nerve impulses in the motor cortex-ADRs-GI upset take with
food, avoid ETOH--(monitor blood levels)
Drugs that affect GABA: benzodiazepines, gabapentin/Neurontin,
topiramate/Topamax, tiagabine/Gabitril- monitor S/I, weight, ability to sweat,
bicarbonate levels, and seizure activity- may cause false+ urine protein,
somnolence, and dizziness
Antidepressants: TCAs, SSRIs, MAOIs, SNRIs, miscellaneous (S/I BBW
all) All Metabolized in the liver
Monoamine Oxidase Inhibitors (MAOIs): phenelzine/Nardil,
isocarboxazid/Marplan, tranylcypromine/Parnate, selegiline/Emsam- 1st
generation, blocks metabolizing enzymes on dopamine, norepinephrine,
serotonin. Fast acting within 2 weeks.
Contraindication includes liver disease, CHF, SRI, SNRI. Avoid tyramine and
This study source was downloaded by 100000848398116 from CourseHero.com on 06-07-2022 10:00:32 GMT -05:00
https://www.coursehero.com/file/77284856/Midterm-Study-Guidedocx/
, NR 565Midterm Study Guide
all food and drugs that could raise BP, no chocolate, caffeine, yogurt, sour
cream, aged meat, and cheese. HTN crisis symptoms include palpitations,
stiff neck, headache, chest tightness, and tachycardia.
This study source was downloaded by 100000848398116 from CourseHero.com on 06-07-2022 10:00:32 GMT -05:00
https://www.coursehero.com/file/77284856/Midterm-Study-Guidedocx/
