PHARM-MIDTERM-FINAL-DRAFT.
1. Fluoroquinolone antibiotics are most likely indicating in which of the
conditions Asthma
Genital infections
Follicular conjunctivitis
GERD
2. Which of the following is most likely an intervention for otitis media?
Amoxicillin
Aspirin
Immunoglobulins
Corticosteroids
3. Which of the following best classifies penicillin, cephalosporins,
and Protein synthesis inhibitors
Mycolic acid synthesis
inhibitors RNA synthesis
Cell wall inhibitors
4. Beta lactamase inhibitors are often located in which of the
following? May decrease absorption
First dose effect
Often combined with penicillin antibiotics
Delayed absorption of oral drugs
5. Which of the following drug classes is/are used in initial hypertension management
of African American population?
Clonidine primary
Beta blockers primary
Thiazide or calcium channel blocker primary
ACE-I primary
ARB primary
6. Which of the following groups of antibiotics is notable for side effects such
as nephrotoxicity or ototoxicity?
Beta-lactams
Aminoglycosides
Tetracyclines
7. Which of the following groups of antibiotics has a beta-lactam ring in the molecular
,PHARM-MIDTERM-FINAL-DRAFT.
Structure
Sulfonamides
Macrolides
Tetracyclines
Fluoroquinolone
Cephalosporins
8. Which of the follow medication is a fluoroquinolone antibiotic?
Ciprofloxacin
Azithromycin
Amikacin
Penicillin
9. Which of the following medications or drugs classes is commonly indicated
for managing gestational hypertension?
Spironolactone (Aldactone)
Loop diuretics
Calcium channel blockers
Dobutamine
Calcium gluconate
10. Which of the following best classifies aminoglycosides, macrolides and
clindamycin? Protein synthesis inhibitor
Folic acid synthesis
inhibitors Cell wall inhibitors
Mycolic acid synthesis inhibitors
11. The long half-life of amiodarone contributes to which
complications Enhanced therapeutic effects
Liver toxicity
Decreased dosing
Short onset of action
12. Pharmacokinetics involves the study of which factor?
Distribution rates among various body
compartment Physiologic interactions of drugs
Interactions among various
drugs Adverse reactions to
medications
,PHARM-MIDTERM-FINAL-DRAFT.
13. Which route of drug administration is used with potent and lipophilic drugs in a
patch formulation and avoids first-pass metabolism?
Oral
Topical
Rectal
Transdermal
14. Patients who have a poor metabolism phenotype will
have: A need for increased dosages of medications
Increased elimination of an active drug
Accumulation of inactive metabolites of drugs
Slowed metabolism of prodrug into an active drug leading to accumulation of prodrug
15. Lower doses of sublingual nitroglycerin can be used effectively because
It bypasses the liver
The potency is 100 times higher
It does not need to be absorbed into the bloodstream
It is not catabolized down by gastric acids
16. Which term refers to the ratio between a drugs therapeutic effects and its toxic
effects? Cumulative effect
Therapeutic index
Tolerance
Affinity
17. In geriatric patients the percentage of body fat is increased. What are the
pharmacologic implications of the physiologic change?
A lipid soluble medication will be eliminated more quickly and not work as well
Absorption of lipid soluble drugs is impaired in older adults.
The bioavailability of the lipid soluble drug will be increased in older adults
A lipid soluble medication will accumulate in fat tissue and its duration of action may
be prolonged
18. A patient diagnosed with otitis externa and taking a fluoroquinolone with
glucocorticoid benefit is taking the medication together you reply
The glucocorticoid reduces the swelling caused by the inflammation and ear infection
The glucocorticoid decreased likelihood of antibiotic resistant
The glucocorticoid decreases the adverse effects of the fluoroquinolone
, PHARM-MIDTERM-FINAL-DRAFT.
The two medications are contraindicated for use together
19. A two year old child presents to the clinic with arthralgia and fever in the last tympanic
membrane is erythematous and bulging the right TMS is perforated and draining the
child’s parent states “this is fifth year infection this year “what can we do? what action will
the provider take to address to Childs ear problems
Prescribe amoxicillin/clavulanate and refer the child to an otolaryngologist??? I THINK
THIS IS CORRECT
Prescribe both ceftriaxone (Rocephin) IM with benzocaine ear drops for pain
20. A patient is diagnosed with otitis externa. Comorbidities include diabetes mellitus,
hypertension, and advanced multiple sclerosis. Which type of education regarding
medication administration would you provide? page 1304 repeat #20
The oral administration of a prescription for hydrocortisone/neomycin/polymyxin B
combination solution
The oral administration of a prescription for fluoroquinolone
The administration of topical medication for a prescription of alcohol plus acetic acid s
solution
The administration of topical combination for a prescription of
fluoroquinolone/glucocorticoid combination solution
21. A patient who has congestive heart failure requires a diuretic. The patient also has a
history of chronic kidney disease with a glomerular filtration rate (FGR) of less than 30
ml/min. which drug would you prescribe this patient.
Methyclothiazide
Metolazone
Loop diuretics
22. Factors released by platelets contribute to hemostasis by
enhancing Fibrinolysis
Vasodilation
Intrinsic pathway
Platelet aggregation
23. A patient has been receiving iron replacement therapy for 2 days after hip
replacement surgery. The provider is alerted to the following assessment data:
1. Fluoroquinolone antibiotics are most likely indicating in which of the
conditions Asthma
Genital infections
Follicular conjunctivitis
GERD
2. Which of the following is most likely an intervention for otitis media?
Amoxicillin
Aspirin
Immunoglobulins
Corticosteroids
3. Which of the following best classifies penicillin, cephalosporins,
and Protein synthesis inhibitors
Mycolic acid synthesis
inhibitors RNA synthesis
Cell wall inhibitors
4. Beta lactamase inhibitors are often located in which of the
following? May decrease absorption
First dose effect
Often combined with penicillin antibiotics
Delayed absorption of oral drugs
5. Which of the following drug classes is/are used in initial hypertension management
of African American population?
Clonidine primary
Beta blockers primary
Thiazide or calcium channel blocker primary
ACE-I primary
ARB primary
6. Which of the following groups of antibiotics is notable for side effects such
as nephrotoxicity or ototoxicity?
Beta-lactams
Aminoglycosides
Tetracyclines
7. Which of the following groups of antibiotics has a beta-lactam ring in the molecular
,PHARM-MIDTERM-FINAL-DRAFT.
Structure
Sulfonamides
Macrolides
Tetracyclines
Fluoroquinolone
Cephalosporins
8. Which of the follow medication is a fluoroquinolone antibiotic?
Ciprofloxacin
Azithromycin
Amikacin
Penicillin
9. Which of the following medications or drugs classes is commonly indicated
for managing gestational hypertension?
Spironolactone (Aldactone)
Loop diuretics
Calcium channel blockers
Dobutamine
Calcium gluconate
10. Which of the following best classifies aminoglycosides, macrolides and
clindamycin? Protein synthesis inhibitor
Folic acid synthesis
inhibitors Cell wall inhibitors
Mycolic acid synthesis inhibitors
11. The long half-life of amiodarone contributes to which
complications Enhanced therapeutic effects
Liver toxicity
Decreased dosing
Short onset of action
12. Pharmacokinetics involves the study of which factor?
Distribution rates among various body
compartment Physiologic interactions of drugs
Interactions among various
drugs Adverse reactions to
medications
,PHARM-MIDTERM-FINAL-DRAFT.
13. Which route of drug administration is used with potent and lipophilic drugs in a
patch formulation and avoids first-pass metabolism?
Oral
Topical
Rectal
Transdermal
14. Patients who have a poor metabolism phenotype will
have: A need for increased dosages of medications
Increased elimination of an active drug
Accumulation of inactive metabolites of drugs
Slowed metabolism of prodrug into an active drug leading to accumulation of prodrug
15. Lower doses of sublingual nitroglycerin can be used effectively because
It bypasses the liver
The potency is 100 times higher
It does not need to be absorbed into the bloodstream
It is not catabolized down by gastric acids
16. Which term refers to the ratio between a drugs therapeutic effects and its toxic
effects? Cumulative effect
Therapeutic index
Tolerance
Affinity
17. In geriatric patients the percentage of body fat is increased. What are the
pharmacologic implications of the physiologic change?
A lipid soluble medication will be eliminated more quickly and not work as well
Absorption of lipid soluble drugs is impaired in older adults.
The bioavailability of the lipid soluble drug will be increased in older adults
A lipid soluble medication will accumulate in fat tissue and its duration of action may
be prolonged
18. A patient diagnosed with otitis externa and taking a fluoroquinolone with
glucocorticoid benefit is taking the medication together you reply
The glucocorticoid reduces the swelling caused by the inflammation and ear infection
The glucocorticoid decreased likelihood of antibiotic resistant
The glucocorticoid decreases the adverse effects of the fluoroquinolone
, PHARM-MIDTERM-FINAL-DRAFT.
The two medications are contraindicated for use together
19. A two year old child presents to the clinic with arthralgia and fever in the last tympanic
membrane is erythematous and bulging the right TMS is perforated and draining the
child’s parent states “this is fifth year infection this year “what can we do? what action will
the provider take to address to Childs ear problems
Prescribe amoxicillin/clavulanate and refer the child to an otolaryngologist??? I THINK
THIS IS CORRECT
Prescribe both ceftriaxone (Rocephin) IM with benzocaine ear drops for pain
20. A patient is diagnosed with otitis externa. Comorbidities include diabetes mellitus,
hypertension, and advanced multiple sclerosis. Which type of education regarding
medication administration would you provide? page 1304 repeat #20
The oral administration of a prescription for hydrocortisone/neomycin/polymyxin B
combination solution
The oral administration of a prescription for fluoroquinolone
The administration of topical medication for a prescription of alcohol plus acetic acid s
solution
The administration of topical combination for a prescription of
fluoroquinolone/glucocorticoid combination solution
21. A patient who has congestive heart failure requires a diuretic. The patient also has a
history of chronic kidney disease with a glomerular filtration rate (FGR) of less than 30
ml/min. which drug would you prescribe this patient.
Methyclothiazide
Metolazone
Loop diuretics
22. Factors released by platelets contribute to hemostasis by
enhancing Fibrinolysis
Vasodilation
Intrinsic pathway
Platelet aggregation
23. A patient has been receiving iron replacement therapy for 2 days after hip
replacement surgery. The provider is alerted to the following assessment data:
