Which characteristic listed below is a CHD risk equivalent; that is, which risk factor
places the patient at similar risk for CHD as a history of CHD?
A) HTN
B) Cigarette Smoking
C) Male age > 45
D) DM - Answer D) diabetes mellitus
In determining whether a patient should be treated for hypercholesterolemia, a patient's
risk category must be determined. After assessing fasting lipids, CHD equivalents must
be identified. These are diabetes, symptomatic CAD, PAD, AAA, and multiple risk
factors that confer a 10 yr risk of CHD >20%.
A patient wants to be screened for hyperlipidemia via a serum specimen. He should be
told:
A) to fast for 12-14 hours
B) to fast for 6-8 hours
C) that black coffee is allowed
D) a non-fasting state won't affect the results - Answer A) to fast for 12-14 hours
Serum total and HDL cholesterol can be measured in fasting or non-fasting individuals.
There are very small and clinically insignificant differences in these values when fasting
and not. The primary effect of eating on lipid values is on the triglyceride value. The
maximum effect of eating on triglyceride levels occurs at 3-4 hours, but there may be
several peaks during a 12 hour period. Therefore, the most accurate levels will be
obtained following a 12 hour fast.
What class of medications will normalize lipid elevations and decrease risk of a cardiac
event?
A) Niacin
B) Fibric acids
C) Statins
D) bile acid sequestrants - Answer C) Statins
The only medication class that lowers elevated lipid levels and has proven efficacy in
lowering risk of cardiac events, even for primary prevention is the statins. Statin therapy
has been shown to reduce overall mortality due to cardiovascular deaths.
Which test listed below may be used to exclude a secondary cause of hyperlipidemia in
a patient with elevated lipids?
A) CBC
B) Urine culture and sensitivity
C) TSH
D) Fasting glucose - Answer C) TSH
Patients who have hypercholesterolemia should be screened for diabetes, renal failure,
and hypothyroidism. Nephrotic syndrome can produce remarkably elevated cholesterol
levels. Therefore, measurements of glucose, creatinine, and TSH should be performed
when evaluating hypercholesterolemia. A single fasting glucose is not used to diagnose
diabetes (a confirmatory reading is always needed for diagnosis) and, therefore, could
, FNP PREP Cardiac questions
not be used in this example to exclude (or include) a secondary cause of
hypercholesterolemia.
In order to lower lipid levels, statins are taken:
A) twice daily
B) always with food
C) with an aspirin
D) in conjunction with diet and exercise - Answer D) in conjunction with diet and
exercise
Statins are used to lower elevated levels of lipids in conjunction with modifications in
diet and exercise. They do not specifically need to be take with or without food or
aspirin. Though, most patients who take statins are also candidates for aspirin as
primary or secondary prevention. Statis are correctly take once daily.
A patient taking lovastatin for hyperlipidemia complains of muscle aches in his thighs
and right calf for the past three days that has not improved. He has taken lovastatin for
3 months. What should be done?
A) Stop the lovastatin immediately
B) Check liver enzymes
C) Order a CPK
D) Ask about nighttime muscle cramps - Answer C) order a CPK
This patient has a complaint of myalgias that could be associated with statin use. This
patient should be assessed for rhabdomyolysis; this is done by measuring a CPK. If this
value is elevated, lovastatin should be stopped immediately. Liver enzymes would not
assess for myalgias. Nighttime muscle cramps are not associated with statin use.
Which hypertensive patient is most likely to have adverse blood pressure effects from
excessive sodium consumption?
A) 21 year old Asian American male
B) 35 year old menstruating female
C) 55 year old post menopausal female
D) 70 year old African American male - Answer D) 70 year old African American Male
Two groups of patients typically experience adverse blood pressure effects from
consumption of sodium greater than 2000 mg daily. Those patients considered to be
most sodium sensitive are elderly patients and African American patients; thus, choice d
is the best choice listed.
A patient with hypertension and myocardial infarction 6 years ago presents today with
mild shortness of breath. He takes quinapril, ASA, metoprolol, and a statin daily. What
symptom is NOT indicative of a CHF exacerbation?
A) Fatigue
B) Headache
C) Orthopnea
D) Cough - Answer B) Headache