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NBME CBSE study guide with complete solutions..

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NBME CBSE study guide with complete solutions..Bulbus cordis Smooth parts (outflow tract) of left and right ventricles endocardial cushions Atrial septum, membranous interventricular septum; AV and semilunar valves neural crest 00:21 01:17 left horn of the sinus venosus coronary sinus posterior, sub cardinal, and supra cardinal veins IVC Right common cardinal vein and right anterior cardinal vein SVC Right horn of sinus venosus Smooth part of right atrium (sinus venarum) Patent foramen ovale failure of septum primum and septum secundum to fuse after birth Transposition of the great vessels Tetralogy of Fallot Persistent truncus arteriosus Conotruncal abnormalities associated with failure of neural crest cells to migrate ductus venosus connects the umbilical vein to the inferior vena cava, bypassing the liver becomes ligamentum venosum phrenic nerve innervates the diaphragm and pericardium S3 heart sound Increased ventricular filling pressure (e.g., mitral regurgitation, HF), common in dilated ventricles normal in kids and pregnant women S4 heart sound atrial kick late diastole, right before S1 best heard at apex in LLD position High atrial pressure. Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy) Always abnormal

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Bulbus cordis - Answer Smooth parts (outflow tract) of left and right ventricles

endocardial cushions - Answer Atrial septum, membranous interventricular septum; AV
and semilunar valves

neural crest

left horn of the sinus venosus - Answer coronary sinus

posterior, sub cardinal, and supra cardinal veins - Answer IVC

Right common cardinal vein and right anterior cardinal vein - Answer SVC

Right horn of sinus venosus - Answer Smooth part of right atrium (sinus venarum)

Patent foramen ovale - Answer failure of septum primum and septum secundum to fuse
after birth

Transposition of the great vessels
Tetralogy of Fallot
Persistent truncus arteriosus - Answer Conotruncal abnormalities associated with failure
of neural crest cells to migrate

ductus venosus - Answer connects the umbilical vein to the inferior vena cava,
bypassing the liver

becomes ligamentum venosum

phrenic nerve - Answer innervates the diaphragm and pericardium

S3 heart sound - Answer Increased ventricular filling pressure (e.g., mitral regurgitation,
HF), common in dilated ventricles

normal in kids and pregnant women

S4 heart sound - Answer atrial kick late diastole, right before S1

best heard at apex in LLD position

High atrial pressure.

Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)

Always abnormal

atria contract - Answer a wave of JVP

,c wave - Answer RV contraction (closed tricuspid valve bulging into atrium) wave of JVP

x descent - Answer JVP wave corresponding to downward displacement of closed
tricuspid valve during rapid ventricular ejection phase

reduced or absent in tricuspid regurge

V wave - Answer JVP wave corresponding to inc'd RA pressure due to filling against
closed tricuspid valve

y descent - Answer JVP wave corresponding to RA emptying into RV

absent in cardiac tamponade

plusus parvus et tardus - Answer pulses are weak with delayed peak

Aortic stenosis

PR interval - Answer 0.12-0.20 seconds

120 milliseconds

QT interval length - Answer 9 - 11 squares = .36 to .44 seconds

Hypokalemia - Answer U wave present on ECG

Mg sulfate - Answer for torsades de pointe, hypokalemia (can lengthen QT and cause
torsades), and pre-eclampsia (prevent seizures)

Romano-Ward syndrome - Answer -Congenital long QT syndrome
-Autosomal dominant, pure cardiac phenotype (no deafness).

Jervell and Lange-Nielsen syndrome - Answer -Congenital long QT syndrome
-Autosomal recessive, sensorineural deafness

Brugada syndrome - Answer -Autosomal dominant disorder affecting Na channels most
common in Asian males.
-ECG pattern of pseudo-right bundle branch block and ST elevations in V1-V3 (anterior
ventricular septum)
-inc risk of ventricular tachyarrhythmias and sudden cardiac deatgh

Prevent SCD with implantable cardioverter-defibrillator (ICD).

Wolff-Parkinson-White Syndrome - Answer Most common type of ventriuclar pre-
excitation sydnrome. Abnormal fast accessory conduction pathway from atria to venricle

, bypasses the rate-slowing AV node causing a delta wave and widening QRS with
shortened PR interval. Could lead to a reentrant circuit and suprvaventicular tachy.

First degree AV block - Answer - PRI >5 boxes/.20 sec (200 msec)
- Fixed but prolonged PRI
(consistent but long)
- normally get bradycardia here

second degree AV block mobitz type 2 - Answer -PR interval is constant
-atrial conduction to ventricle is intermittent: dropped QRS without increasing PR
interval length
-disease below AV node in His bundle

may progress to 3rd degree/complete AV block

Second Degree AV Block Mobitz Type 1 (wenckebach) - Answer Progressive
lengthening of pr interval leading to dropped QRS

third degree AV block - Answer The atria and Ventricles are totally dissociated.
-So, the QRSs and the P waves have no relation to each other.

PCWP - Answer 4-12 mmHg
est of LA pressure

Williams Syndrome - Answer a genetic condition characterized by mental retardation in
most regards but surprisingly good use of language relative to their other abilities, elfin
facies
Chromosome 7
assoc with supravalvular aortic stenosis

DiGeorge Syndrome - Answer Maldevelopment of 3 and 4 pharyngeal pouches, fascial
dysmorphia, cardiac shunt (trunks arteriosus, tetralogy of Fallot), lack of T-cells,
undeveloped paracortex

Corneal arcus - Answer Lipid deposits in the cornea. Common in the elderly, but
appears earlier in life with hypercholesterolemia

Stanford A aortic dissection - Answer Dissection of the ascending aorta
Tx with surgery

Stanford B aortic dissection - Answer Dissection of the descending aorta below the level
o the left subclavian artery
Tx: Beta Blockers then vasodilators

Left bundle branch block - Answer QRS> 120 msec
Deep, broad S waves in V1 and V2

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