CHEM 3700 EXAM 1
An electrostatic interaction would be expected to have a bond distance of
approximately_________. –
3Å
The bond dissociation energy of a C-C covalent bond is approximately ____ -
350 kJ/mol
Water has a _____ molecular structure. –
bent
Each water molecule has____ hydrogen bond donor(s)? –
2
The molecule cyclohexane (C6H12) is designated as ____ relative to water. –
hydrophobic
Water ionization has a Keq value of ____ at 25°C. –
1.8 x 10^-16
(#7 2015)
If the proton concentration in an aqueous (H2O) solution is decreased by 100x, what
happens to the pH of the solution. –
it goes up by 2 units
The pKa for formic acid is 3.77. If a solution is made to be 0.2 M in formic acid and 0.1
M sodium formate, what is the pH of the solution? –
3.5
pH= 3.77 + log (0.1/0.2)
pH= 3.47
(#9 2015)
The net charge on the amino acid His is ___ at pH 5.0? –
+1
(#10 2015)
The amino acid enantiomer used in most proteins is _____? –
L
A Ramachandran plot shows _____ on the y axis and ____ on the x axis? –
, Psi bond angle, Phi bond angle
The protein alpha helix has a pitch of approximately ______ Å. –
5.4
H bonding in the protein beta secondary structure is between ________. –
an NH group and an C=O group in the same polypeptide
Protein tertiary structure can be stabilized by all of the following except _____ -
nuclear interactions
An enzyme is found to contain three different polypeptides. Which of the following would
be an appropriate representation for the quaternary structure __________? –
α2β2γ2
What can be said about a chemical reaction that is exergonic? –
it is spontaneous as written
Enzymes catalyze a reaction by _________. –
stabilizing the transition state
Which of the following would be appropriate units for the rate of an enzyme catalyzed
reaction? –
μmoles product formed/sec
Which of the following would be appropriate units for Km for an enzyme catalyzed
reaction. –
μM
Which of the following changes for an enzyme catalyzed reaction when a non-
competitive inhibitor is added? –
Max
An enzyme is found to contain an organic compound that is a derivative of a B vitamin.
What can be said about this bound derivative? –
it is a co-enzyme
For hemoglobin, the binding of an O2 to the ____of the heme results in a protein
conformational change that alter the binding of O2 to the other three subunits. –
Fe
The effect of binding of one O2 to hemoglobin on the binding of subsequent O2
molecules is an example of ________ regulation? –
allosteric
The pH of a solution is found to be 11.4. What is the [H+] of the solution? –
An electrostatic interaction would be expected to have a bond distance of
approximately_________. –
3Å
The bond dissociation energy of a C-C covalent bond is approximately ____ -
350 kJ/mol
Water has a _____ molecular structure. –
bent
Each water molecule has____ hydrogen bond donor(s)? –
2
The molecule cyclohexane (C6H12) is designated as ____ relative to water. –
hydrophobic
Water ionization has a Keq value of ____ at 25°C. –
1.8 x 10^-16
(#7 2015)
If the proton concentration in an aqueous (H2O) solution is decreased by 100x, what
happens to the pH of the solution. –
it goes up by 2 units
The pKa for formic acid is 3.77. If a solution is made to be 0.2 M in formic acid and 0.1
M sodium formate, what is the pH of the solution? –
3.5
pH= 3.77 + log (0.1/0.2)
pH= 3.47
(#9 2015)
The net charge on the amino acid His is ___ at pH 5.0? –
+1
(#10 2015)
The amino acid enantiomer used in most proteins is _____? –
L
A Ramachandran plot shows _____ on the y axis and ____ on the x axis? –
, Psi bond angle, Phi bond angle
The protein alpha helix has a pitch of approximately ______ Å. –
5.4
H bonding in the protein beta secondary structure is between ________. –
an NH group and an C=O group in the same polypeptide
Protein tertiary structure can be stabilized by all of the following except _____ -
nuclear interactions
An enzyme is found to contain three different polypeptides. Which of the following would
be an appropriate representation for the quaternary structure __________? –
α2β2γ2
What can be said about a chemical reaction that is exergonic? –
it is spontaneous as written
Enzymes catalyze a reaction by _________. –
stabilizing the transition state
Which of the following would be appropriate units for the rate of an enzyme catalyzed
reaction? –
μmoles product formed/sec
Which of the following would be appropriate units for Km for an enzyme catalyzed
reaction. –
μM
Which of the following changes for an enzyme catalyzed reaction when a non-
competitive inhibitor is added? –
Max
An enzyme is found to contain an organic compound that is a derivative of a B vitamin.
What can be said about this bound derivative? –
it is a co-enzyme
For hemoglobin, the binding of an O2 to the ____of the heme results in a protein
conformational change that alter the binding of O2 to the other three subunits. –
Fe
The effect of binding of one O2 to hemoglobin on the binding of subsequent O2
molecules is an example of ________ regulation? –
allosteric
The pH of a solution is found to be 11.4. What is the [H+] of the solution? –
